IE41622L - Carboxy acetamidocephalosporins - Google Patents

Carboxy acetamidocephalosporins

Info

Publication number
IE41622L
IE41622L IE751145A IE114575A IE41622L IE 41622 L IE41622 L IE 41622L IE 751145 A IE751145 A IE 751145A IE 114575 A IE114575 A IE 114575A IE 41622 L IE41622 L IE 41622L
Authority
IE
Ireland
Prior art keywords
compounds
tert
butyl
converting
monoester
Prior art date
Application number
IE751145A
Other versions
IE41622B1 (en
Original Assignee
Rech Et Ind Therapeutique R I
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rech Et Ind Therapeutique R I filed Critical Rech Et Ind Therapeutique R I
Publication of IE41622L publication Critical patent/IE41622L/en
Publication of IE41622B1 publication Critical patent/IE41622B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

1457237 Cephem compounds RECHERCHE ET INDUSTRIE THERAPEUTIQUES 21 May 1975 [22 May 1974 2 Jan 1975] 21816/75 Heading C2C The invention comprises compounds of formula and their non-toxic pharmaceutically acceptable salts. In examples, these compounds are prepared by converting benzyl or tert-butyl thienylacetate to the corresponding malonate monoester, converting this to monobenzyl (or tert - butyl)mono(2,5 - dioxopyrrolidin - 1 - yl)- thienylmalonate, reacting the latter with the corresponding amino / methyltetrazolylthiomethyl cephen compound, and finally hydrolysing the thus-formed side-chain monoester of I. Thereapeutic compositions having antibacterial activity comprise compounds of the above formula and may be administered by injection. [GB1457237A]
IE1145/75A 1974-05-22 1975-05-22 Cephalosporin compounds IE41622B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US47226374A 1974-05-22 1974-05-22
US53798775A 1975-01-02 1975-01-02

Publications (2)

Publication Number Publication Date
IE41622L true IE41622L (en) 1975-11-22
IE41622B1 IE41622B1 (en) 1980-02-13

Family

ID=27043712

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1145/75A IE41622B1 (en) 1974-05-22 1975-05-22 Cephalosporin compounds

Country Status (13)

Country Link
JP (1) JPS511489A (en)
AU (1) AU8059475A (en)
CA (1) CA1041087A (en)
DE (1) DE2521062A1 (en)
DK (1) DK203575A (en)
ES (1) ES437182A1 (en)
FR (1) FR2271827A1 (en)
GB (1) GB1457237A (en)
IE (1) IE41622B1 (en)
IL (1) IL47176A0 (en)
LU (1) LU72530A1 (en)
NL (1) NL7505962A (en)
SE (1) SE7504669L (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5321191A (en) * 1976-08-10 1978-02-27 Shionogi & Co Ltd 7-arylmalonamidocephem derivatives
JPS60215690A (en) * 1984-04-09 1985-10-29 Meiji Seika Kaisha Ltd Cephalosporin compound and antibacterial agent containing said compound as active component

Also Published As

Publication number Publication date
ES437182A1 (en) 1977-01-16
CA1041087A (en) 1978-10-24
GB1457237A (en) 1976-12-01
IL47176A0 (en) 1975-06-25
NL7505962A (en) 1975-11-25
JPS511489A (en) 1976-01-08
FR2271827A1 (en) 1975-12-19
LU72530A1 (en) 1975-10-08
DK203575A (en) 1975-11-23
DE2521062A1 (en) 1975-12-04
IE41622B1 (en) 1980-02-13
SE7504669L (en) 1975-11-24
AU8059475A (en) 1976-11-04

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