GB1361967A - Pyrazine 4-oxide derivatives and process for their preparation - Google Patents
Pyrazine 4-oxide derivatives and process for their preparationInfo
- Publication number
- GB1361967A GB1361967A GB1764573A GB1764573A GB1361967A GB 1361967 A GB1361967 A GB 1361967A GB 1764573 A GB1764573 A GB 1764573A GB 1764573 A GB1764573 A GB 1764573A GB 1361967 A GB1361967 A GB 1361967A
- Authority
- GB
- United Kingdom
- Prior art keywords
- general formula
- compound
- group
- pyrazine
- april
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Epoxy Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT2366372 | 1972-04-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1361967A true GB1361967A (en) | 1974-07-30 |
Family
ID=11208983
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1764573A Expired GB1361967A (en) | 1972-04-28 | 1973-04-12 | Pyrazine 4-oxide derivatives and process for their preparation |
Country Status (21)
Country | Link |
---|---|
JP (1) | JPS5535384B2 (pt) |
AT (1) | AT326669B (pt) |
AU (1) | AU470007B2 (pt) |
BE (1) | BE798752A (pt) |
CA (1) | CA1000278A (pt) |
CH (1) | CH582161A5 (pt) |
CS (1) | CS172972B2 (pt) |
DE (1) | DE2319834C3 (pt) |
DK (1) | DK138796B (pt) |
FI (1) | FI55033C (pt) |
FR (1) | FR2183049B1 (pt) |
GB (1) | GB1361967A (pt) |
HK (1) | HK66876A (pt) |
HU (1) | HU165674B (pt) |
IL (1) | IL42026A (pt) |
MY (1) | MY7700077A (pt) |
NL (1) | NL178595C (pt) |
NO (1) | NO137728C (pt) |
SE (1) | SE387344B (pt) |
SU (1) | SU578876A3 (pt) |
ZA (1) | ZA732712B (pt) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3219407A1 (de) * | 1981-05-28 | 1983-01-05 | Farmitalia Carlo Erba S.p.A., 20159 Milano | Verfahren zur herstellung von pyrazinderivaten |
EP0088395A1 (en) * | 1982-03-08 | 1983-09-14 | FARMITALIA CARLO ERBA S.p.A. | A process for the preparation of pyrazine derivatives |
US4962111A (en) * | 1989-06-08 | 1990-10-09 | The Research Foundation Of State University Of New York | Pyrazinoic acid esters as antituberculosis agents |
US5643912A (en) * | 1993-12-17 | 1997-07-01 | The Research Foundation Of State University Of Ny | Pyrazinoic acid esters as anti-mycobacterium avium agents |
WO2021203572A1 (zh) * | 2020-04-08 | 2021-10-14 | 山东新时代药业有限公司 | 一种 1,2- 二 (4- 吡啶基 ) 乙烷 - 阿昔莫司共晶 |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1094287B (it) * | 1978-03-23 | 1985-07-26 | Erba Carlo Spa | Derivati della 2-idrossimetil-pirazina aventi attivita' ipolipemizzante |
GB2133004B (en) * | 1982-11-04 | 1986-06-11 | Ici Plc | Process for the extraction of metal values and novel metal extractants |
IT1201417B (it) * | 1985-05-17 | 1989-02-02 | Montedison Spa | Procedimento per la preparazione di 2-carbossipirazine 4 ossido |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3452014A (en) * | 1964-08-14 | 1969-06-24 | Upjohn Co | 2,5-dimethylpyrazine p-toluenesulfonate |
AT291264B (de) * | 1969-05-05 | 1971-07-12 | Daiichi Seiyaku Company Ltd | Verfahren zur Herstellung von neuen Pyrazincarbonsäurederivaten |
NL6907199A (en) * | 1969-05-09 | 1970-11-11 | Hypoglycaemic pyrazine derivs |
-
1973
- 1973-04-12 GB GB1764573A patent/GB1361967A/en not_active Expired
- 1973-04-12 AU AU54413/73A patent/AU470007B2/en not_active Expired
- 1973-04-13 IL IL42026A patent/IL42026A/en unknown
- 1973-04-18 AT AT345073A patent/AT326669B/de active Protection Beyond IP Right Term
- 1973-04-18 DE DE2319834A patent/DE2319834C3/de not_active Expired
- 1973-04-19 ZA ZA732712A patent/ZA732712B/xx unknown
- 1973-04-24 CS CS2929A patent/CS172972B2/cs unknown
- 1973-04-25 NO NO1705/73A patent/NO137728C/no unknown
- 1973-04-26 BE BE130442A patent/BE798752A/xx not_active IP Right Cessation
- 1973-04-26 JP JP4832373A patent/JPS5535384B2/ja not_active Expired
- 1973-04-26 FI FI1336/73A patent/FI55033C/fi active
- 1973-04-26 NL NLAANVRAGE7305867,A patent/NL178595C/xx not_active IP Right Cessation
- 1973-04-27 HU HUEA129A patent/HU165674B/hu unknown
- 1973-04-27 SU SU7301908970A patent/SU578876A3/ru active
- 1973-04-27 FR FR7315308A patent/FR2183049B1/fr not_active Expired
- 1973-04-27 CA CA169,694A patent/CA1000278A/en not_active Expired
- 1973-04-27 SE SE7305965A patent/SE387344B/xx unknown
- 1973-04-27 CH CH605873A patent/CH582161A5/xx active Protection Beyond IP Right Term
- 1973-04-27 DK DK232573AA patent/DK138796B/da not_active IP Right Cessation
-
1976
- 1976-10-28 HK HK668/76*UA patent/HK66876A/xx unknown
-
1977
- 1977-12-30 MY MY77/77A patent/MY7700077A/xx unknown
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3219407A1 (de) * | 1981-05-28 | 1983-01-05 | Farmitalia Carlo Erba S.p.A., 20159 Milano | Verfahren zur herstellung von pyrazinderivaten |
EP0088395A1 (en) * | 1982-03-08 | 1983-09-14 | FARMITALIA CARLO ERBA S.p.A. | A process for the preparation of pyrazine derivatives |
US4511718A (en) * | 1982-03-08 | 1985-04-16 | Farmitalia Carlo Erba S.P.A. | Preparation of pyrazine derivatives |
US4962111A (en) * | 1989-06-08 | 1990-10-09 | The Research Foundation Of State University Of New York | Pyrazinoic acid esters as antituberculosis agents |
US5643912A (en) * | 1993-12-17 | 1997-07-01 | The Research Foundation Of State University Of Ny | Pyrazinoic acid esters as anti-mycobacterium avium agents |
WO2021203572A1 (zh) * | 2020-04-08 | 2021-10-14 | 山东新时代药业有限公司 | 一种 1,2- 二 (4- 吡啶基 ) 乙烷 - 阿昔莫司共晶 |
Also Published As
Publication number | Publication date |
---|---|
NL178595B (nl) | 1985-11-18 |
ZA732712B (en) | 1974-11-27 |
CH582161A5 (pt) | 1976-11-30 |
FI55033B (fi) | 1979-01-31 |
FR2183049A1 (pt) | 1973-12-14 |
NO137728B (no) | 1978-01-02 |
NO137728C (no) | 1978-04-12 |
SU578876A3 (ru) | 1977-10-30 |
CA1000278A (en) | 1976-11-23 |
IL42026A0 (en) | 1973-06-29 |
FR2183049B1 (pt) | 1975-10-31 |
JPS5535384B2 (pt) | 1980-09-12 |
HK66876A (en) | 1976-11-05 |
SE387344B (sv) | 1976-09-06 |
JPS4954386A (pt) | 1974-05-27 |
AT326669B (de) | 1975-12-29 |
DK138796B (da) | 1978-10-30 |
FI55033C (fi) | 1979-05-10 |
IL42026A (en) | 1976-07-30 |
AU5441373A (en) | 1974-10-17 |
BE798752A (fr) | 1973-08-16 |
MY7700077A (en) | 1977-12-31 |
AU470007B2 (en) | 1976-02-26 |
CS172972B2 (pt) | 1977-01-28 |
DK138796C (pt) | 1979-04-30 |
ATA345073A (de) | 1975-03-15 |
NL7305867A (pt) | 1973-10-30 |
DE2319834B2 (de) | 1982-06-24 |
NL178595C (nl) | 1986-04-16 |
DE2319834A1 (de) | 1973-11-15 |
HU165674B (pt) | 1974-10-28 |
DE2319834C3 (de) | 1983-02-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed [section 19, patents act 1949] | ||
732 | Registration of transactions, instruments or events in the register (sect. 32/1977) | ||
PE20 | Patent expired after termination of 20 years |
Effective date: 19930411 |