AU470007B2 - Pyrazine 4-oxide derivatives and process for their preparation - Google Patents

Pyrazine 4-oxide derivatives and process for their preparation

Info

Publication number
AU470007B2
AU470007B2 AU54413/73A AU5441373A AU470007B2 AU 470007 B2 AU470007 B2 AU 470007B2 AU 54413/73 A AU54413/73 A AU 54413/73A AU 5441373 A AU5441373 A AU 5441373A AU 470007 B2 AU470007 B2 AU 470007B2
Authority
AU
Australia
Prior art keywords
pyrazine
preparation
oxide derivatives
derivatives
oxide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU54413/73A
Other languages
English (en)
Other versions
AU5441373A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmitalia Carlo Erba SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmitalia Carlo Erba SRL filed Critical Farmitalia Carlo Erba SRL
Publication of AU5441373A publication Critical patent/AU5441373A/en
Application granted granted Critical
Publication of AU470007B2 publication Critical patent/AU470007B2/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AU54413/73A 1972-04-28 1973-04-12 Pyrazine 4-oxide derivatives and process for their preparation Expired AU470007B2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2366372 1972-04-28

Publications (2)

Publication Number Publication Date
AU5441373A AU5441373A (en) 1974-10-17
AU470007B2 true AU470007B2 (en) 1976-02-26

Family

ID=11208983

Family Applications (1)

Application Number Title Priority Date Filing Date
AU54413/73A Expired AU470007B2 (en) 1972-04-28 1973-04-12 Pyrazine 4-oxide derivatives and process for their preparation

Country Status (21)

Country Link
JP (1) JPS5535384B2 (pt)
AT (1) AT326669B (pt)
AU (1) AU470007B2 (pt)
BE (1) BE798752A (pt)
CA (1) CA1000278A (pt)
CH (1) CH582161A5 (pt)
CS (1) CS172972B2 (pt)
DE (1) DE2319834C3 (pt)
DK (1) DK138796B (pt)
FI (1) FI55033C (pt)
FR (1) FR2183049B1 (pt)
GB (1) GB1361967A (pt)
HK (1) HK66876A (pt)
HU (1) HU165674B (pt)
IL (1) IL42026A (pt)
MY (1) MY7700077A (pt)
NL (1) NL178595C (pt)
NO (1) NO137728C (pt)
SE (1) SE387344B (pt)
SU (1) SU578876A3 (pt)
ZA (1) ZA732712B (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1094287B (it) * 1978-03-23 1985-07-26 Erba Carlo Spa Derivati della 2-idrossimetil-pirazina aventi attivita' ipolipemizzante
NL8202105A (nl) * 1981-05-28 1982-12-16 Erba Farmitalia Werkwijze voor het bereiden van pyrazinederivaten.
CA1205075A (en) * 1982-03-08 1986-05-27 Claudio Santini Preparation of pyrazine derivatives
GB2133004B (en) * 1982-11-04 1986-06-11 Ici Plc Process for the extraction of metal values and novel metal extractants
IT1201417B (it) * 1985-05-17 1989-02-02 Montedison Spa Procedimento per la preparazione di 2-carbossipirazine 4 ossido
US4962111A (en) * 1989-06-08 1990-10-09 The Research Foundation Of State University Of New York Pyrazinoic acid esters as antituberculosis agents
US5643912A (en) * 1993-12-17 1997-07-01 The Research Foundation Of State University Of Ny Pyrazinoic acid esters as anti-mycobacterium avium agents
CN113493421A (zh) * 2020-04-08 2021-10-12 鲁南制药集团股份有限公司 一种1,2-二(4-吡啶基)乙烷-阿昔莫司共晶

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3452014A (en) * 1964-08-14 1969-06-24 Upjohn Co 2,5-dimethylpyrazine p-toluenesulfonate
AT291264B (de) * 1969-05-05 1971-07-12 Daiichi Seiyaku Company Ltd Verfahren zur Herstellung von neuen Pyrazincarbonsäurederivaten
NL6907199A (en) * 1969-05-09 1970-11-11 Hypoglycaemic pyrazine derivs

Also Published As

Publication number Publication date
MY7700077A (en) 1977-12-31
NO137728C (no) 1978-04-12
NL178595C (nl) 1986-04-16
IL42026A0 (en) 1973-06-29
IL42026A (en) 1976-07-30
HK66876A (en) 1976-11-05
SE387344B (sv) 1976-09-06
GB1361967A (en) 1974-07-30
DE2319834C3 (de) 1983-02-03
NO137728B (no) 1978-01-02
CA1000278A (en) 1976-11-23
DK138796C (pt) 1979-04-30
FI55033B (fi) 1979-01-31
AU5441373A (en) 1974-10-17
FR2183049B1 (pt) 1975-10-31
SU578876A3 (ru) 1977-10-30
JPS5535384B2 (pt) 1980-09-12
DE2319834A1 (de) 1973-11-15
NL7305867A (pt) 1973-10-30
DE2319834B2 (de) 1982-06-24
DK138796B (da) 1978-10-30
JPS4954386A (pt) 1974-05-27
HU165674B (pt) 1974-10-28
CS172972B2 (pt) 1977-01-28
FR2183049A1 (pt) 1973-12-14
ZA732712B (en) 1974-11-27
AT326669B (de) 1975-12-29
NL178595B (nl) 1985-11-18
CH582161A5 (pt) 1976-11-30
BE798752A (fr) 1973-08-16
FI55033C (fi) 1979-05-10
ATA345073A (de) 1975-03-15

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