GB1356470A - Ortho-disubstituted aryl-guanidines process for their preparation and applications thereof - Google Patents

Ortho-disubstituted aryl-guanidines process for their preparation and applications thereof

Info

Publication number
GB1356470A
GB1356470A GB1851071*[A GB1851071A GB1356470A GB 1356470 A GB1356470 A GB 1356470A GB 1851071 A GB1851071 A GB 1851071A GB 1356470 A GB1356470 A GB 1356470A
Authority
GB
United Kingdom
Prior art keywords
preparation
dichlorophenyl
guanidines
ortho
applications
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1851071*[A
Other languages
English (en)
Inventor
J Schwartz
C G Wermuth
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Seperic SA
Original Assignee
Seperic SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Seperic SA filed Critical Seperic SA
Priority to GB1851071*[A priority Critical patent/GB1356470A/en
Priority to CH755872A priority patent/CH554319A/fr
Priority to ZA723523A priority patent/ZA723523B/xx
Priority to IE690/72A priority patent/IE36383B1/xx
Priority to DK265372AA priority patent/DK129987B/da
Priority to OA54584A priority patent/OA04093A/xx
Priority to FR7219188A priority patent/FR2140060B1/fr
Priority to AT463372A priority patent/AT314555B/de
Priority to NL7207269A priority patent/NL7207269A/xx
Priority to JP5255972A priority patent/JPS5521740B2/ja
Priority to SE7207080A priority patent/SE375524B/xx
Priority to DE19722226590 priority patent/DE2226590A1/de
Priority to LU65442D priority patent/LU65442A1/xx
Priority to BE784259A priority patent/BE784259A/xx
Priority to CA143,747A priority patent/CA970391A/en
Priority to AU43059/72A priority patent/AU462814B2/en
Publication of GB1356470A publication Critical patent/GB1356470A/en
Priority to US05/553,155 priority patent/US4011342A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/18Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to carbon atoms of six-membered aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB1851071*[A 1971-06-02 1971-06-02 Ortho-disubstituted aryl-guanidines process for their preparation and applications thereof Expired GB1356470A (en)

Priority Applications (17)

Application Number Priority Date Filing Date Title
GB1851071*[A GB1356470A (en) 1971-06-02 1971-06-02 Ortho-disubstituted aryl-guanidines process for their preparation and applications thereof
CH755872A CH554319A (fr) 1971-06-02 1972-05-23 Procede de preparation d'aryl-guanidines ortho-disubstituees.
ZA723523A ZA723523B (en) 1971-06-02 1972-05-23 Ortho-disubstituted aryl guanidines,process for their preparation and applications thereof
IE690/72A IE36383B1 (en) 1971-06-02 1972-05-23 Improvements in or relating to ortho-disubstituted arylguanidines process for their preparation and applications thereof
DK265372AA DK129987B (da) 1971-06-02 1972-05-26 Analogifremgangsmåde til fremstilling af guanidiner.
OA54584A OA04093A (fr) 1971-06-02 1972-05-27 Procédé de préparation d'aryl-guanidines ortho-disubstituées.
JP5255972A JPS5521740B2 (ja) 1971-06-02 1972-05-29
AT463372A AT314555B (de) 1971-06-02 1972-05-29 Verfahren zur Herstellung von neuen Guanidinen
NL7207269A NL7207269A (ja) 1971-06-02 1972-05-29
FR7219188A FR2140060B1 (ja) 1971-06-02 1972-05-29
SE7207080A SE375524B (ja) 1971-06-02 1972-05-30
DE19722226590 DE2226590A1 (de) 1971-06-02 1972-05-31 Ortho-disubstituierte Arylguanidine, Verfahren zu deren Herstellung und deren Verwendung
LU65442D LU65442A1 (ja) 1971-06-02 1972-05-31
BE784259A BE784259A (fr) 1971-06-02 1972-06-01 Aryl-guanidines ortho-disubstituees, leur procede de preparation et leurs applications
CA143,747A CA970391A (en) 1971-06-02 1972-06-02 Process of preparation of ortho-disubstituted aryl-guanidines
AU43059/72A AU462814B2 (en) 1971-06-02 1972-06-02 Ortho-disubstituted aryl-guanidines process for their preparation and applications thereof
US05/553,155 US4011342A (en) 1971-06-02 1975-02-26 Method and composition for the treatment of hypertension with ortho-disubstituted arylguanidines

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1851071*[A GB1356470A (en) 1971-06-02 1971-06-02 Ortho-disubstituted aryl-guanidines process for their preparation and applications thereof

Publications (1)

Publication Number Publication Date
GB1356470A true GB1356470A (en) 1974-06-12

Family

ID=10113667

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1851071*[A Expired GB1356470A (en) 1971-06-02 1971-06-02 Ortho-disubstituted aryl-guanidines process for their preparation and applications thereof

Country Status (16)

Country Link
JP (1) JPS5521740B2 (ja)
AT (1) AT314555B (ja)
AU (1) AU462814B2 (ja)
BE (1) BE784259A (ja)
CA (1) CA970391A (ja)
CH (1) CH554319A (ja)
DE (1) DE2226590A1 (ja)
DK (1) DK129987B (ja)
FR (1) FR2140060B1 (ja)
GB (1) GB1356470A (ja)
IE (1) IE36383B1 (ja)
LU (1) LU65442A1 (ja)
NL (1) NL7207269A (ja)
OA (1) OA04093A (ja)
SE (1) SE375524B (ja)
ZA (1) ZA723523B (ja)

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014091384A2 (en) * 2012-12-12 2014-06-19 Mahesh Kandula Compositions and methods for the treatment of mucositis
US9096537B1 (en) 2014-12-31 2015-08-04 Mahesh Kandula Compositions and methods for the treatment of mucositis
US9102649B1 (en) 2014-09-29 2015-08-11 Mahesh Kandula Compositions and methods for the treatment of multiple sclerosis
US9174931B2 (en) 2013-06-04 2015-11-03 Cellix Bio Private Limited Compositions for the treatment of diabetes and pre-diabetes
US9206111B1 (en) 2014-12-17 2015-12-08 Cellix Bio Private Limited Compositions and methods for the treatment of neurological diseases
US9333187B1 (en) 2013-05-15 2016-05-10 Cellix Bio Private Limited Compositions and methods for the treatment of inflammatory bowel disease
US9403793B2 (en) 2012-07-03 2016-08-02 Cellix Bio Private Limited Compositions and methods for the treatment of moderate to severe pain
US9725404B2 (en) 2014-10-27 2017-08-08 Cellix Bio Private Limited Compositions and methods for the treatment of multiple sclerosis
US9771355B2 (en) 2014-09-26 2017-09-26 Cellix Bio Private Limited Compositions and methods for the treatment of epilepsy and neurological disorders
US9932294B2 (en) 2014-12-01 2018-04-03 Cellix Bio Private Limited Compositions and methods for the treatment of multiple sclerosis
US10343994B2 (en) 2015-01-06 2019-07-09 Mahesh Kandula Compositions and methods for the treatment of inflammation and pain

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0117190Y2 (ja) * 1979-04-20 1989-05-18
FR2549049B1 (fr) * 1983-07-13 1986-06-20 Chauvin Blache Lab Nouvelles amidines, leur procede de preparation et leur application therapeutique
EP2852571A4 (en) * 2012-05-23 2015-11-25 Cellix Bio Private Ltd COMPOSITIONS AND METHOD FOR THE TREATMENT OF MUCOSITIS

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1542792B2 (de) * 1965-11-09 1974-08-01 Bayer Ag, 5090 Leverkusen Verwendung von Monoarylguanidinen zur Abwehr von Vögeln, Nagetieren und hasenartigen Tieren
DE1619538B1 (de) * 1967-08-04 1971-06-24 Bayer Ag Verfahren zum Färben von Fasermaterialien aus Polyacrylnitril oder acrylnitrilhaltigen Mischpolymerisaten

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9403793B2 (en) 2012-07-03 2016-08-02 Cellix Bio Private Limited Compositions and methods for the treatment of moderate to severe pain
WO2014091384A3 (en) * 2012-12-12 2014-12-24 Mahesh Kandula Compositions and methods for the treatment of mucositis
WO2014091384A2 (en) * 2012-12-12 2014-06-19 Mahesh Kandula Compositions and methods for the treatment of mucositis
US9333187B1 (en) 2013-05-15 2016-05-10 Cellix Bio Private Limited Compositions and methods for the treatment of inflammatory bowel disease
US9174931B2 (en) 2013-06-04 2015-11-03 Cellix Bio Private Limited Compositions for the treatment of diabetes and pre-diabetes
US9840472B2 (en) 2013-12-07 2017-12-12 Cellix Bio Private Limited Compositions and methods for the treatment of mucositis
US9771355B2 (en) 2014-09-26 2017-09-26 Cellix Bio Private Limited Compositions and methods for the treatment of epilepsy and neurological disorders
US9102649B1 (en) 2014-09-29 2015-08-11 Mahesh Kandula Compositions and methods for the treatment of multiple sclerosis
US9988340B2 (en) 2014-09-29 2018-06-05 Cellix Bio Private Limited Compositions and methods for the treatment of multiple sclerosis
US9725404B2 (en) 2014-10-27 2017-08-08 Cellix Bio Private Limited Compositions and methods for the treatment of multiple sclerosis
US9932294B2 (en) 2014-12-01 2018-04-03 Cellix Bio Private Limited Compositions and methods for the treatment of multiple sclerosis
US9206111B1 (en) 2014-12-17 2015-12-08 Cellix Bio Private Limited Compositions and methods for the treatment of neurological diseases
US9096537B1 (en) 2014-12-31 2015-08-04 Mahesh Kandula Compositions and methods for the treatment of mucositis
US10343994B2 (en) 2015-01-06 2019-07-09 Mahesh Kandula Compositions and methods for the treatment of inflammation and pain

Also Published As

Publication number Publication date
BE784259A (fr) 1972-10-02
DK129987C (ja) 1975-06-02
DK129987B (da) 1974-12-09
IE36383L (en) 1972-12-02
JPS5521740B2 (ja) 1980-06-12
IE36383B1 (en) 1976-10-27
AT314555B (de) 1974-04-10
NL7207269A (ja) 1972-12-05
FR2140060A1 (ja) 1973-01-12
AU4305972A (en) 1973-12-13
CA970391A (en) 1975-07-01
ZA723523B (en) 1973-03-28
OA04093A (fr) 1979-10-30
LU65442A1 (ja) 1972-08-24
SE375524B (ja) 1975-04-21
FR2140060B1 (ja) 1975-10-17
JPS4828434A (ja) 1973-04-14
AU462814B2 (en) 1975-06-23
CH554319A (fr) 1974-09-30
DE2226590A1 (de) 1972-12-14

Similar Documents

Publication Publication Date Title
NO176101C (no) Analogifremgangsmåte for fremstilling av terapeutisk aktive N-(3-hydroksy-4-piperidinyl)(dihydrobenzofuran, dihydro-2H-benzopyran eller dihydrobenzodioksin)karboksamidderivater
GB1356470A (en) Ortho-disubstituted aryl-guanidines process for their preparation and applications thereof
HUT50322A (en) Process for producing substituted quinazoline derivatives and pharmaceutical compositions comprising such compounds
GB1464326A (en) Benzimidazole carbamates
FI884375A0 (fi) Menetelmä terapeuttisesti käyttökelpoisten N-(1-alkyyli-3-hydroksi-4-piperidinyyli)bentsamidien valmistamiseksi
GB1083193A (en) Guanidine derivatives and process for their manufacture
GB1388358A (en) Taste-improving formulations of oral penicillins
GB1374367A (en) Propionamide derivative a method of making it and therapeutic compositions containing it
GB1155549A (en) A Sulphur-containing Amine and Process for its Manufacture
GB1438095A (en) 2-substituted-5,6-dimethoxyindazoles their preparation and compositions containing them
GB1350710A (en) Ureas and thioureas
GB1476698A (en) Quinazolinone derivatives and therapeutic compositions containing them
GB1322112A (en) 3,4,5-trimethoxybenzoic acid derivatives and their uses
GB1280290A (en) Novel derivatives of benzhydrylpiperazine, their process of preparation and their therapeutic application
GB1351437A (en) N-substituted amino acids having antiviral anti-inflammatory or anti-tumour activity
IE31997B1 (en) New substituted 2-arylalkyloxy-benzamides and the preparation thereof
GB1449070A (en) Aminotetralins and use in inducing anesthesia
GB1451389A (en) Indolobenzazepines
GB1470747A (en) Pyridazine derivative
GB985635A (en) Guanidine derivatives and process for their production
GB1420976A (en) Pharmaceutical compositions for use in the treatment of certain respiratory diseases or conditions in prematurely born children
GB1346795A (en) Nitrilotriacyltriimino-tris-2,4,6-triidobenzoic acid compounds
GB1243955A (en) Novel n-substituted amines and their process of preparation
IE32154B1 (en) N-(tertiary amino-alkyl)-2-alkenyl (or alkynyl)-oxy benzamides and a process for the preparation thereof
GB1313838A (en) 3,4,5-trialkoxybenzoic acid derivatives and their uses

Legal Events

Date Code Title Description
PS Patent sealed
435 Patent endorsed 'licences of right' on the date specified (sect. 35/1949)
PCNP Patent ceased through non-payment of renewal fee