GB1351409A - Sustained release pharmaceutical compositions for topical appli cation - Google Patents

Sustained release pharmaceutical compositions for topical appli cation

Info

Publication number
GB1351409A
GB1351409A GB839572A GB839572A GB1351409A GB 1351409 A GB1351409 A GB 1351409A GB 839572 A GB839572 A GB 839572A GB 839572 A GB839572 A GB 839572A GB 1351409 A GB1351409 A GB 1351409A
Authority
GB
United Kingdom
Prior art keywords
drug
sustained release
polymer
release pharmaceutical
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB839572A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
EIDP Inc
Original Assignee
EI Du Pont de Nemours and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by EI Du Pont de Nemours and Co filed Critical EI Du Pont de Nemours and Co
Publication of GB1351409A publication Critical patent/GB1351409A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/02—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
    • C08G63/06—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxycarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A61K9/204—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7015—Drug-containing film-forming compositions, e.g. spray-on

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Polyesters Or Polycarbonates (AREA)
GB839572A 1971-02-23 1972-02-23 Sustained release pharmaceutical compositions for topical appli cation Expired GB1351409A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11808171A 1971-02-23 1971-02-23

Publications (1)

Publication Number Publication Date
GB1351409A true GB1351409A (en) 1974-05-01

Family

ID=22376416

Family Applications (1)

Application Number Title Priority Date Filing Date
GB839572A Expired GB1351409A (en) 1971-02-23 1972-02-23 Sustained release pharmaceutical compositions for topical appli cation

Country Status (5)

Country Link
US (1) US3755558A (enExample)
CA (1) CA950828A (enExample)
DE (1) DE2207635A1 (enExample)
FR (1) FR2126270B1 (enExample)
GB (1) GB1351409A (enExample)

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0094513A3 (en) * 1982-05-14 1984-08-22 Akzo Gmbh Sustained-release body containing an active ingredient
US4491575A (en) * 1982-10-15 1985-01-01 Chemie Linz Aktiengesellschaft Compressed products with retarded release of active substance, a process for their preparation and a process for the long-term administration of medicaments
US4526938A (en) * 1982-04-22 1985-07-02 Imperial Chemical Industries Plc Continuous release formulations
US4849228A (en) * 1985-05-07 1989-07-18 Takeda Chemical Industries, Ltd. Polymer, production and use thereof
US5247058A (en) * 1992-01-24 1993-09-21 Cargill, Incorporated Continuous process for manufacture of lactide polymers with controlled optical purity
US5247059A (en) * 1992-01-24 1993-09-21 Cargill, Incorporated Continuous process for the manufacture of a purified lactide from esters of lactic acid
US5258488A (en) * 1992-01-24 1993-11-02 Cargill, Incorporated Continuous process for manufacture of lactide polymers with controlled optical purity
US5274073A (en) * 1992-01-24 1993-12-28 Cargill, Incorporated Continuous process for manufacture of a purified lactide
US5338822A (en) * 1992-10-02 1994-08-16 Cargill, Incorporated Melt-stable lactide polymer composition and process for manufacture thereof
US5525706A (en) * 1992-10-02 1996-06-11 Cargill, Incorporated Melt-stable lactide polymer nonwoven fabric and process for manufacture thereof
US5665474A (en) * 1992-10-02 1997-09-09 Cargill, Incorporated Paper having a melt-stable lactide polymer coating and process for manufacture thereof
US6005068A (en) * 1992-10-02 1999-12-21 Cargill Incorporated Melt-stable amorphous lactide polymer film and process for manufacture thereof
US6005067A (en) * 1992-01-24 1999-12-21 Cargill Incorporated Continuous process for manufacture of lactide polymers with controlled optical purity
US6323307B1 (en) 1988-08-08 2001-11-27 Cargill Dow Polymers, Llc Degradation control of environmentally degradable disposable materials
US6326458B1 (en) 1992-01-24 2001-12-04 Cargill, Inc. Continuous process for the manufacture of lactide and lactide polymers
US6528093B1 (en) 1992-12-07 2003-03-04 Takeda Chemical Industries, Ltd. Sustained-release preparation

Families Citing this family (103)

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US3962414A (en) * 1972-04-27 1976-06-08 Alza Corporation Structured bioerodible drug delivery device
US3914402A (en) * 1973-06-14 1975-10-21 Alza Corp Ophthalmic dosage form, for releasing medication over time
US4001388A (en) * 1973-06-14 1977-01-04 Alza Corporation Ophthalmological bioerodible drug dispensing formulation
AR205997A1 (es) * 1973-11-21 1976-06-23 American Cyanamid Co Resina de poliester normalmente solida biodegradable e hidrolizable
US3960152A (en) * 1974-01-21 1976-06-01 American Cyanamid Company Surgical sutures of unsymmetrically substituted 1,4-dioxane-2,5-diones
US4076798A (en) * 1975-05-29 1978-02-28 American Cyanamid Company High molecular weight polyester resin, the method of making the same and the use thereof as a pharmaceutical composition
US4011312A (en) * 1975-06-25 1977-03-08 American Home Products Corporation Prolonged release drug form for the treatment of bovine mastitis
GB1556710A (en) * 1975-09-12 1979-11-28 Anic Spa Method of occluding substances in structures and products obtained thereby
US4115544A (en) * 1976-08-18 1978-09-19 Alza Corporation Ocular system made of bioerodible esters having linear ether
US4328204A (en) * 1977-03-02 1982-05-04 Ethicon, Inc. Absorbable polymer-drug compounds and method for making same
DE2856901D2 (de) * 1977-06-07 1980-11-13 Garching Instrumente Form of implant medicament and preparation process
US4186189A (en) * 1977-09-28 1980-01-29 Ethicon, Inc. Absorbable pharmaceutical compositions based on poly(alkylene oxalates)
US4732763A (en) * 1978-10-17 1988-03-22 Stolle Research And Development Corporation Active/passive immunization of the internal female reproductive organs
US4585651A (en) * 1978-10-17 1986-04-29 Stolle Research & Development Corporation Active/passive immunization of the internal female reproductive organs
US4293539A (en) * 1979-09-12 1981-10-06 Eli Lilly And Company Controlled release formulations and method of treatment
AU534665B2 (en) * 1979-09-12 1984-02-09 Eli Lilly And Company Method
AU539230B2 (en) * 1979-09-12 1984-09-20 Eli Lilly And Company Parasitic formulations and method
US5248700A (en) * 1982-05-14 1993-09-28 Akzo Nv Active agent containing solid structures for prolonged release of active agents
JPS6045522B2 (ja) * 1982-12-08 1985-10-09 憲司 中村 化粧用具
JPH0798755B2 (ja) * 1985-11-27 1995-10-25 エチコン・インコ−ポレ−テツド 局所的投与により術後の癒着形成を抑制するための組成物
IN166447B (enExample) * 1985-11-27 1990-05-12 Ethicon Inc
CA1297791C (en) * 1985-12-16 1992-03-24 Warren Douglas Sheffield Method for inhibiting post-surgical adhesion formation by the topical administration of tissue plasminogen activator
US4889722A (en) * 1985-12-16 1989-12-26 Ethicon, Inc. Method for inhibiting post-surgical adhesion formation by the topical administration of tissue plasminogen activator
EP0234897A3 (en) * 1986-02-24 1987-11-19 Ethicon, Inc. Inhibition of post-surgical adhesion formation by the continual topical administration of glucocorticoid
DE3620685A1 (de) * 1986-06-20 1987-12-23 Henkel Kgaa Neue mittel zur abdeckung unverletzter und/oder verletzter bereiche menschlicher oder tierischer haut
US5985354A (en) 1995-06-07 1999-11-16 Brown University Research Foundation Preparation of multiwall polymeric microcapsules from hydrophilic polymers
DE3734223A1 (de) * 1987-10-09 1989-04-20 Boehringer Ingelheim Kg Implantierbares, biologisch abbaubares wirkstofffreigabesystem
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US5180765A (en) * 1988-08-08 1993-01-19 Biopak Technology, Ltd. Biodegradable packaging thermoplastics from lactides
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US5502158A (en) * 1988-08-08 1996-03-26 Ecopol, Llc Degradable polymer composition
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US5725491A (en) * 1988-10-03 1998-03-10 Atrix Laboratories, Inc. Method of forming a biodegradable film dressing on tissue
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US5632727A (en) * 1988-10-03 1997-05-27 Atrix Laboratories, Inc. Biodegradable film dressing and method for its formation
US5633002A (en) * 1988-10-04 1997-05-27 Boehringer Ingelheim Gmbh Implantable, biodegradable system for releasing active substance
US5487897A (en) 1989-07-24 1996-01-30 Atrix Laboratories, Inc. Biodegradable implant precursor
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DE4229924C2 (de) * 1991-04-17 1995-12-07 Juergens Christian Dr Med Verwendung von resorbierbaren Lactidcopolymeren
TW247878B (enExample) * 1991-07-02 1995-05-21 Takeda Pharm Industry Co Ltd
US6013853A (en) * 1992-02-14 2000-01-11 The University Of Texas System Continuous release polymeric implant carrier
US5876452A (en) * 1992-02-14 1999-03-02 Board Of Regents, University Of Texas System Biodegradable implant
EP0560014A1 (en) * 1992-03-12 1993-09-15 Atrix Laboratories, Inc. Biodegradable film dressing and method for its formation
US5576418A (en) * 1992-06-29 1996-11-19 Jurgens; Christian Resorbable biocompatible copolymers and their use
US5700485A (en) 1992-09-10 1997-12-23 Children's Medical Center Corporation Prolonged nerve blockade by the combination of local anesthetic and glucocorticoid
US5922340A (en) * 1992-09-10 1999-07-13 Children's Medical Center Corporation High load formulations and methods for providing prolonged local anesthesia
AU683022B2 (en) * 1992-09-10 1997-10-30 Children's Medical Center Corporation Biodegradable polymer matrices for sustained delivery of local anesthetic agents
US5714573A (en) * 1995-01-19 1998-02-03 Cargill, Incorporated Impact modified melt-stable lactide polymer compositions and processes for manufacture thereof
US5618850A (en) * 1995-03-09 1997-04-08 Focal, Inc. Hydroxy-acid cosmetics
US5722950A (en) * 1995-06-07 1998-03-03 Atrix Laboratories, Inc. Method for remote delivery of an aerosolized liquid
CN1156961A (zh) 1995-06-09 1997-08-13 欧罗赛铁克股份有限公司 产生长效局部麻醉的制剂和方法
DE19600095A1 (de) 1996-01-03 1997-07-10 Christian Dr Med Juergens Verwendung von Lactidpolymeren zur Adhäsionsprophylaxe
WO1997049391A1 (en) 1996-06-24 1997-12-31 Euro-Celtique, S.A. Methods for providing safe local anesthesia
US5756651A (en) * 1996-07-17 1998-05-26 Chronopol, Inc. Impact modified polylactide
US6046187A (en) 1996-09-16 2000-04-04 Children's Medical Center Corporation Formulations and methods for providing prolonged local anesthesia
US5955097A (en) * 1996-10-18 1999-09-21 Virotex Corporation Pharmaceutical preparation applicable to mucosal surfaces and body tissues
US5858531A (en) * 1996-10-24 1999-01-12 Bio Syntech Method for preparation of polymer microparticles free of organic solvent traces
US6126919A (en) * 1997-02-07 2000-10-03 3M Innovative Properties Company Biocompatible compounds for pharmaceutical drug delivery systems
US5945126A (en) * 1997-02-13 1999-08-31 Oakwood Laboratories L.L.C. Continuous microsphere process
KR100367144B1 (ko) 1997-07-02 2003-01-14 유로-셀티크 소시에떼 아노뉨 관절과 체강(ｂｏｄｙ ｓｐａｃｅ)내에서 연장된 마취
US7128927B1 (en) 1998-04-14 2006-10-31 Qlt Usa, Inc. Emulsions for in-situ delivery systems
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US6143314A (en) * 1998-10-28 2000-11-07 Atrix Laboratories, Inc. Controlled release liquid delivery compositions with low initial drug burst
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ATE322513T1 (de) * 2000-08-07 2006-04-15 Wako Pure Chem Ind Ltd Milchsäurepolymer und verfahren zu dessen herstellung
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US20110033542A1 (en) 2009-08-07 2011-02-10 Monosol Rx, Llc Sublingual and buccal film compositions
US8900497B2 (en) 2001-10-12 2014-12-02 Monosol Rx, Llc Process for making a film having a substantially uniform distribution of components
US8603514B2 (en) 2002-04-11 2013-12-10 Monosol Rx, Llc Uniform films for rapid dissolve dosage form incorporating taste-masking compositions
US7357891B2 (en) 2001-10-12 2008-04-15 Monosol Rx, Llc Process for making an ingestible film
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Cited By (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4526938A (en) * 1982-04-22 1985-07-02 Imperial Chemical Industries Plc Continuous release formulations
EP0094513A3 (en) * 1982-05-14 1984-08-22 Akzo Gmbh Sustained-release body containing an active ingredient
US4491575A (en) * 1982-10-15 1985-01-01 Chemie Linz Aktiengesellschaft Compressed products with retarded release of active substance, a process for their preparation and a process for the long-term administration of medicaments
US4849228A (en) * 1985-05-07 1989-07-18 Takeda Chemical Industries, Ltd. Polymer, production and use thereof
US6323307B1 (en) 1988-08-08 2001-11-27 Cargill Dow Polymers, Llc Degradation control of environmentally degradable disposable materials
US5258488A (en) * 1992-01-24 1993-11-02 Cargill, Incorporated Continuous process for manufacture of lactide polymers with controlled optical purity
US5247059A (en) * 1992-01-24 1993-09-21 Cargill, Incorporated Continuous process for the manufacture of a purified lactide from esters of lactic acid
US5274073A (en) * 1992-01-24 1993-12-28 Cargill, Incorporated Continuous process for manufacture of a purified lactide
US6326458B1 (en) 1992-01-24 2001-12-04 Cargill, Inc. Continuous process for the manufacture of lactide and lactide polymers
US5357035A (en) * 1992-01-24 1994-10-18 Cargill, Incorporated Continuous process for manufacture of lactide polymers with purification by distillation
US5247058A (en) * 1992-01-24 1993-09-21 Cargill, Incorporated Continuous process for manufacture of lactide polymers with controlled optical purity
US6277951B1 (en) 1992-01-24 2001-08-21 Cargill, Incorporated Continuous process for manufacture of lactide polymers with controlled optical purity
US6005067A (en) * 1992-01-24 1999-12-21 Cargill Incorporated Continuous process for manufacture of lactide polymers with controlled optical purity
US5773562A (en) * 1992-10-02 1998-06-30 Cargill, Incorporated Melt-stable semi-crystalline lactide polymer film and process for manufacture thereof
US6093791A (en) * 1992-10-02 2000-07-25 Cargill, Incorporated Melt-stable semi-crystalline lactide polymer film and process for manufacture thereof
US5665474A (en) * 1992-10-02 1997-09-09 Cargill, Incorporated Paper having a melt-stable lactide polymer coating and process for manufacture thereof
US5536807A (en) * 1992-10-02 1996-07-16 Cargill, Incorporated Melt-stable semi-crystalline lactide polymer film and process for manufacture thereof
US5798436A (en) * 1992-10-02 1998-08-25 Cargill, Incorporated Melt-stable amorphous lactide polymer film and process for manufacture thereof
US5807973A (en) * 1992-10-02 1998-09-15 Cargill, Incorporated Melt-stable lactide polymer nonwoven fabric and process for manufacture thereof
US5852166A (en) * 1992-10-02 1998-12-22 Cargill, Incorporated Paper having a melt-stable lactide polymer coating and process for manufacture thereof
US6005068A (en) * 1992-10-02 1999-12-21 Cargill Incorporated Melt-stable amorphous lactide polymer film and process for manufacture thereof
US5525706A (en) * 1992-10-02 1996-06-11 Cargill, Incorporated Melt-stable lactide polymer nonwoven fabric and process for manufacture thereof
US5585191A (en) * 1992-10-02 1996-12-17 Cargill, Incorporated Melt-stable amorphous lactide polymer film and process for manufacture thereof
US6111060A (en) * 1992-10-02 2000-08-29 Cargill, Incorporated Melt-stable lactide polymer nonwoven fabric and process for manufacture thereof
US6121410A (en) * 1992-10-02 2000-09-19 Cargill, Incorporated Melt-stable semi-crystalline lactide polymer film and process for manufacture thereof
US6207792B1 (en) 1992-10-02 2001-03-27 Cargill, Incorporated Melt-stable amorphous lactide polymer film and process for manufacture thereof
US5484881A (en) * 1992-10-02 1996-01-16 Cargill, Inc. Melt-stable amorphous lactide polymer film and process for manufacturing thereof
US5475080A (en) * 1992-10-02 1995-12-12 Cargill, Incorporated Paper having a melt-stable lactide polymer coating and process for manufacture thereof
US5338822A (en) * 1992-10-02 1994-08-16 Cargill, Incorporated Melt-stable lactide polymer composition and process for manufacture thereof
US6355772B1 (en) 1992-10-02 2002-03-12 Cargill, Incorporated Melt-stable lactide polymer nonwoven fabric and process for manufacture thereof
US6528093B1 (en) 1992-12-07 2003-03-04 Takeda Chemical Industries, Ltd. Sustained-release preparation
US7048947B2 (en) 1992-12-07 2006-05-23 Takeda Pharmaceutical Company Limited Sustained-release preparation

Also Published As

Publication number Publication date
DE2207635A1 (de) 1972-08-31
US3755558A (en) 1973-08-28
FR2126270A1 (enExample) 1972-10-06
CA950828A (en) 1974-07-09
FR2126270B1 (enExample) 1975-11-28

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