IE41417L - Stabilized steroid formulations - Google Patents
Stabilized steroid formulationsInfo
- Publication number
- IE41417L IE41417L IE751175A IE117575A IE41417L IE 41417 L IE41417 L IE 41417L IE 751175 A IE751175 A IE 751175A IE 117575 A IE117575 A IE 117575A IE 41417 L IE41417 L IE 41417L
- Authority
- IE
- Ireland
- Prior art keywords
- polyethylene glycol
- weight
- compositions
- stabilized
- steroid
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/0026—Oxygen-containing hetero ring cyclic ketals
- C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
1497836 Stabilized steroid compositions ER SQUIBB & SONS INC 29 May 1975 [13 June 1974] 23485/75 Heading A5B Stabilized steroid compositions useful in the treatment of inflammatory diseases of the skin and psoriasis comprises from 0.1% to 0.5% by weight of 9 α - fluoro - 21 - chloro - 11#, 16α, 17α, trihydroxypregn - 4 - ene - 3, 20 - dione, 16, 17 - acetonide, 0.005 to 0.2% by weight of an antioxidant selected from propyl gallate, butylated hydroxytoluene, butylated hydroxyanisole, sodium bisulphite, sodium metabisulphite and ascorbic acid; and polyethylene glycol or a polyethylene glycol ester both having a polyethylene glycol molecular weight of from 200 to 7500 may be prepared by dissolving the steroid and antioxidant in the polyethylene glycol or polyethylene glycol ester. The composition may further include an oleaginous material e.g. mineral oil thickened with polyethylene or white petrolatum, a chelating agent such as disodium ethylene diamine tetraacetic acid and/or water. The compositions may be applied topically in the form of lotions or ointments.
[GB1497836A]
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US47898574A | 1974-06-13 | 1974-06-13 |
Publications (2)
Publication Number | Publication Date |
---|---|
IE41417L true IE41417L (en) | 1975-12-13 |
IE41417B1 IE41417B1 (en) | 1980-01-02 |
Family
ID=23902198
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IE1175/75A IE41417B1 (en) | 1974-06-13 | 1975-05-26 | Stabilized steroid formulations |
Country Status (11)
Country | Link |
---|---|
JP (1) | JPS5126216A (en) |
BE (1) | BE830239A (en) |
CA (1) | CA1040534A (en) |
DE (1) | DE2526251A1 (en) |
FR (1) | FR2274310A1 (en) |
GB (1) | GB1497836A (en) |
IE (1) | IE41417B1 (en) |
NL (1) | NL7506872A (en) |
PH (1) | PH14507A (en) |
YU (1) | YU152175A (en) |
ZA (1) | ZA753429B (en) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5612306A (en) * | 1979-07-12 | 1981-02-06 | Nippon Zoki Pharmaceut Co Ltd | Novel base for external preparation |
JPS56135416A (en) * | 1980-03-27 | 1981-10-22 | Mitsubishi Chem Ind Ltd | Pharmaceutical preparation for skin |
JPH10502362A (en) * | 1994-07-04 | 1998-03-03 | シエーリング アクチエンゲゼルシヤフト | Low-dose steroid tablets containing gallic acid ester as antioxidant, method for preparing the same and use thereof |
US7189759B2 (en) * | 2001-05-23 | 2007-03-13 | Medicis Pharmaceutical Corporation | Compositions for the treatment of pigmentation disorders and methods for their manufacture |
DE102004059880A1 (en) * | 2004-12-10 | 2006-06-14 | Grünenthal GmbH | Stable, hormone-containing (intermediate) product |
CN107427465A (en) * | 2015-02-05 | 2017-12-01 | 马克·赛尔纳尔 | Ionic nano vesicle suspension and the biocide from its preparation |
-
1975
- 1975-05-26 IE IE1175/75A patent/IE41417B1/en unknown
- 1975-05-27 ZA ZA00753429A patent/ZA753429B/en unknown
- 1975-05-28 CA CA227,942A patent/CA1040534A/en not_active Expired
- 1975-05-29 GB GB23485/75A patent/GB1497836A/en not_active Expired
- 1975-05-30 PH PH17207A patent/PH14507A/en unknown
- 1975-06-10 NL NL7506872A patent/NL7506872A/en not_active Application Discontinuation
- 1975-06-12 YU YU01521/75A patent/YU152175A/en unknown
- 1975-06-12 DE DE19752526251 patent/DE2526251A1/en not_active Ceased
- 1975-06-13 BE BE157333A patent/BE830239A/en not_active IP Right Cessation
- 1975-06-13 JP JP50072615A patent/JPS5126216A/en active Granted
- 1975-06-13 FR FR7518635A patent/FR2274310A1/en active Granted
Also Published As
Publication number | Publication date |
---|---|
ZA753429B (en) | 1976-04-28 |
YU152175A (en) | 1983-10-31 |
FR2274310A1 (en) | 1976-01-09 |
DE2526251A1 (en) | 1976-01-02 |
CA1040534A (en) | 1978-10-17 |
PH14507A (en) | 1981-08-21 |
AU8168175A (en) | 1976-12-02 |
BE830239A (en) | 1975-10-01 |
IE41417B1 (en) | 1980-01-02 |
JPS5126216A (en) | 1976-03-04 |
NL7506872A (en) | 1975-12-16 |
GB1497836A (en) | 1978-01-12 |
JPS5747971B2 (en) | 1982-10-13 |
FR2274310B1 (en) | 1980-05-16 |
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