GB1326360A - Nitrofuryl-pyrazolopyrimidinones - Google Patents
Nitrofuryl-pyrazolopyrimidinonesInfo
- Publication number
- GB1326360A GB1326360A GB5266369A GB1326360DA GB1326360A GB 1326360 A GB1326360 A GB 1326360A GB 5266369 A GB5266369 A GB 5266369A GB 1326360D A GB1326360D A GB 1326360DA GB 1326360 A GB1326360 A GB 1326360A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- compound
- nitrofuryl
- reacting
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- HBHNWWFFPFMTQD-UHFFFAOYSA-N 5-(furan-2-yl)-7-nitropyrazolo[4,3-d]pyrimidin-3-one Chemical class [N+](=O)([O-])C1=NC(=NC2=C1N=NC2=O)C=1OC=CC=1 HBHNWWFFPFMTQD-UHFFFAOYSA-N 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 9
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 4
- 238000002955 isolation Methods 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- JPIPRHICKKLMOR-UHFFFAOYSA-N 5-(furan-2-yl)-4-nitro-1h-pyrazole Chemical compound [O-][N+](=O)C1=CNN=C1C1=CC=CO1 JPIPRHICKKLMOR-UHFFFAOYSA-N 0.000 abstract 2
- 150000008065 acid anhydrides Chemical class 0.000 abstract 2
- 229910021529 ammonia Inorganic materials 0.000 abstract 2
- 239000003054 catalyst Substances 0.000 abstract 2
- BDAGIHXWWSANSR-UHFFFAOYSA-N methanoic acid Natural products OC=O BDAGIHXWWSANSR-UHFFFAOYSA-N 0.000 abstract 2
- 125000006705 (C5-C7) cycloalkyl group Chemical group 0.000 abstract 1
- AFAGCRFMNWJMBH-UHFFFAOYSA-N 3-(furan-2-yl)-4-nitropyrazolo[3,4-d]oxazine Chemical compound [N+](=O)([O-])C1=C2C(C=NO1)=NN=C2C=2OC=CC2 AFAGCRFMNWJMBH-UHFFFAOYSA-N 0.000 abstract 1
- OSWFIVFLDKOXQC-UHFFFAOYSA-N 4-(3-methoxyphenyl)aniline Chemical compound COC1=CC=CC(C=2C=CC(N)=CC=2)=C1 OSWFIVFLDKOXQC-UHFFFAOYSA-N 0.000 abstract 1
- 239000003377 acid catalyst Substances 0.000 abstract 1
- 230000002378 acidificating effect Effects 0.000 abstract 1
- 230000010933 acylation Effects 0.000 abstract 1
- 238000005917 acylation reaction Methods 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000003302 alkenyloxy group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 230000000845 anti-microbial effect Effects 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000001246 bromo group Chemical group Br* 0.000 abstract 1
- 150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 235000019253 formic acid Nutrition 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 238000011065 in-situ storage Methods 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Earth Drilling (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Catalysts (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB5266369 | 1969-10-28 | ||
| GB4305470 | 1970-09-09 | ||
| GB4305670 | 1970-09-09 | ||
| GB4305570 | 1970-09-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1326360A true GB1326360A (en) | 1973-08-08 |
Family
ID=27448964
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB5266369A Expired GB1326360A (en) | 1969-10-28 | 1969-10-28 | Nitrofuryl-pyrazolopyrimidinones |
Country Status (17)
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4282361A (en) * | 1978-03-16 | 1981-08-04 | Massachusetts Institute Of Technology | Synthesis for 7-alkylamino-3-methylpyrazolo [4,3-d]pyrimidines |
| KR100843526B1 (ko) * | 2004-02-27 | 2008-07-03 | 에프. 호프만-라 로슈 아게 | 피라졸의 접합 유도체 |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3888887A (en) * | 1972-01-14 | 1975-06-10 | American Home Prod | Derivatives of 3-amino-2-halo-2-cyclohexen-1-one |
| AR205234A1 (es) * | 1974-05-13 | 1976-04-12 | Lilly Co Eli | Procedimiento p a r a preparar compuestos de 3-(5-nitroimidazol-2-il) pirazolo (3,4-d) pirimidina |
| US3980794A (en) * | 1974-05-13 | 1976-09-14 | Eli Lilly And Company | Method for promoting growth of poultry with 3-(5-nitro-2-imidazolyl)pyrazoles |
| US4044130A (en) * | 1974-07-03 | 1977-08-23 | Ciba-Geigy Corporation | Compositions for the control of microorganisms |
| ATA210876A (de) * | 1975-03-25 | 1979-01-15 | Byk Gulden Lomberg Chem Fab | Verfahren zur herstellung von neuen nidrofuryl- pyrazolderivaten |
| DE2747531A1 (de) * | 1977-10-22 | 1979-04-26 | Basf Ag | Substituierte 3-aminopyrazole |
| US5656629A (en) * | 1995-03-10 | 1997-08-12 | Sanofi Winthrop, Inc. | 6-substituted pyrazolo (3,4-d)pyrimidin-4-ones and compositions and methods of use thereof |
| JP2007523937A (ja) | 2004-02-27 | 2007-08-23 | エフ．ホフマン−ラ ロシュ アーゲー | インダゾール誘導体およびそれを含む医薬組成物 |
| EP1720878A1 (en) | 2004-02-27 | 2006-11-15 | F.Hoffmann-La Roche Ag | Heteroaryl-fused pyrazolo derivatives |
| CA2620105A1 (en) | 2005-08-25 | 2007-03-01 | F. Hoffman-La Roche Ag | P38 map kinase inhibitors and methods for using the same |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR4032E (fr) * | 1902-10-22 | 1905-05-03 | Francois Louis Dit Amedee Gira | Appareil pour la commande automatique des registres de tirage des générateurs, pouvant assurer aussi la fumivorité |
| CH398626A (de) * | 1960-05-11 | 1966-03-15 | Ciba Geigy | Verfahren zur Herstellung neuer Pyrazolopyrimidine |
| AT229863B (de) * | 1961-10-11 | 1963-10-25 | Norwich Pharma Co | Verfahren zur Herstellung des neuen 2-(5-Nitro-2-furyl)-imidazo-[1,2-a]-pyridins bzw. -pyrimidins |
| DE1295560B (de) * | 1963-07-24 | 1969-05-22 | Heyden Chem Fab | Verfahren zur Herstellung von substituierten 5-Aminopyrazolen |
| US3335141A (en) * | 1964-08-17 | 1967-08-08 | Norwich Pharma Co | 4-substituted-1-alkyl-6-(5-nitro-2-furyl)-1h-pyrazolo[3, 4-d]pyrimidines |
| FR206F (enrdf_load_stackoverflow) * | 1965-07-20 |
-
0
- BE BE758050D patent/BE758050A/xx unknown
-
1969
- 1969-10-28 GB GB5266369A patent/GB1326360A/en not_active Expired
-
1970
- 1970-10-12 CH CH1873872A patent/CH549599A/xx not_active IP Right Cessation
- 1970-10-12 CH CH1496870A patent/CH548412A/xx not_active IP Right Cessation
- 1970-10-12 CH CH1873672A patent/CH549597A/xx not_active IP Right Cessation
- 1970-10-12 CH CH1873572A patent/CH572053A5/xx not_active IP Right Cessation
- 1970-10-12 CH CH1873772A patent/CH549598A/xx not_active IP Right Cessation
- 1970-10-21 NL NL7015412A patent/NL7015412A/xx not_active Application Discontinuation
- 1970-10-21 SE SE7014182A patent/SE383747B/xx unknown
- 1970-10-21 DK DK535970AA patent/DK130589B/da unknown
- 1970-10-21 NO NO03985/70A patent/NO130007B/no unknown
- 1970-10-27 AT AT472471A patent/AT305994B/de not_active IP Right Cessation
- 1970-10-27 AT AT472671A patent/AT304519B/de not_active IP Right Cessation
- 1970-10-27 FR FR707038696A patent/FR2070170B1/fr not_active Expired
- 1970-10-27 AT AT472371A patent/AT303715B/de not_active IP Right Cessation
- 1970-10-27 US US00084531A patent/US3755324A/en not_active Expired - Lifetime
- 1970-10-27 US US00084512A patent/US3716555A/en not_active Expired - Lifetime
- 1970-10-27 RO RO64798A patent/RO56795A/ro unknown
- 1970-10-27 IE IE1371/70A patent/IE34623B1/xx unknown
- 1970-10-27 AT AT472171A patent/AT303714B/de not_active IP Right Cessation
- 1970-10-27 AT AT472571A patent/AT304518B/de not_active IP Right Cessation
- 1970-10-27 BG BG015927A patent/BG17005A3/xx unknown
- 1970-10-27 IL IL35542A patent/IL35542A/xx unknown
- 1970-10-27 DE DE19702064874 patent/DE2064874A1/de active Pending
- 1970-10-27 DE DE19702052719 patent/DE2052719A1/de active Pending
- 1970-10-27 AT AT963670A patent/AT299179B/de active
- 1970-10-27 AT AT472271A patent/AT304517B/de not_active IP Right Cessation
-
1974
- 1974-01-17 SE SE7400605A patent/SE402591B/xx unknown
-
1976
- 1976-05-31 KE KE2638*UA patent/KE2638A/xx unknown
- 1976-08-19 HK HK520/76*UA patent/HK52076A/xx unknown
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4282361A (en) * | 1978-03-16 | 1981-08-04 | Massachusetts Institute Of Technology | Synthesis for 7-alkylamino-3-methylpyrazolo [4,3-d]pyrimidines |
| KR100843526B1 (ko) * | 2004-02-27 | 2008-07-03 | 에프. 호프만-라 로슈 아게 | 피라졸의 접합 유도체 |
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB1326360A (en) | Nitrofuryl-pyrazolopyrimidinones | |
| GB1412130A (en) | 3-substituted-morphinan derivatives | |
| ES454693A1 (es) | Procedimiento para la obtencion de materiales sinteticos inorganico-organicos. | |
| GB1115750A (en) | Process for the production of cyanoalkylated phenols | |
| ES413266A1 (es) | Un procedimiento para la preparacion de un derivado de aci-do indenilacetico. | |
| GB1051917A (enrdf_load_stackoverflow) | ||
| ES8106708A1 (es) | Un procedimiento para preparar 7-alcoxicarbonil-6,8-dime- til-4-hidroximetil-1-ftalazona | |
| GB1226250A (enrdf_load_stackoverflow) | ||
| ES293930A1 (es) | Un procedimiento para la preparaciën de penicilinas | |
| GB1387908A (en) | Polymerisable anthranilic acid esters | |
| GB1194598A (en) | Benzofuran Derivatives | |
| ES317079A1 (es) | Un procedimiento para la preparaciën en penicilinas | |
| GB1379795A (en) | Process for the manufacture of dimethylmaleic anhydride | |
| GB1220781A (en) | Process for the production of nitriles | |
| GB1377274A (en) | Production of o -aminobenzonitrile | |
| GB1305025A (enrdf_load_stackoverflow) | ||
| GB1211556A (en) | 0,2,4-oxdiazolidine derivatives, process for their production and herbicidal compositions containing same | |
| ES319942A1 (es) | Procedimiento para la obtencion de 3 ',4',5'-trimetoxi-3-aminoacrilofenona. | |
| GB1509733A (en) | Process for the manufacture of nitro-amino-azobenzenes | |
| GB1263677A (en) | Process for the preparation of quinoxaline-di-n-oxide-aldehyde | |
| GB1275882A (en) | Process for preparing malononitrile derivatives | |
| GB1270741A (en) | Dihydroxyarylene-bis-mercapto-acetic acid bis-lactones | |
| GB1305550A (enrdf_load_stackoverflow) | ||
| GB1353952A (en) | Production of 5-aminopyrazoles | |
| GB1193347A (en) | Production of Alkylenealdehyde-Substituted Hexahydropyrimidin-2-Ones and -Thiones |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |