GB1321316A - Nitrofuryl-thienopyrimidines - Google Patents

Nitrofuryl-thienopyrimidines

Info

Publication number
GB1321316A
GB1321316A GB5614670A GB5614670A GB1321316A GB 1321316 A GB1321316 A GB 1321316A GB 5614670 A GB5614670 A GB 5614670A GB 5614670 A GB5614670 A GB 5614670A GB 1321316 A GB1321316 A GB 1321316A
Authority
GB
United Kingdom
Prior art keywords
group
carbon atoms
formula
reacting
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB5614670A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19691959403 external-priority patent/DE1959403A1/de
Priority claimed from DE19702050814 external-priority patent/DE2050814A1/de
Priority claimed from DE19702050815 external-priority patent/DE2050815A1/de
Priority claimed from DE19702050816 external-priority patent/DE2050816A1/de
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of GB1321316A publication Critical patent/GB1321316A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
GB5614670A 1969-11-26 1970-11-25 Nitrofuryl-thienopyrimidines Expired GB1321316A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19691959403 DE1959403A1 (de) 1969-11-26 1969-11-26 Neue 2-(5-Nitro-2-furyl)-thieno[3,2-d]pyrimidine und Verfahren zu ihrer Herstellung
DE19702050814 DE2050814A1 (de) 1970-10-16 1970-10-16 Neue Verfahren zur Herstellung von 2-(5-Nitro-2-furyl)-thieno eckige Klammer auf 3,2-d eckige Klammer zu pyrimidinen
DE19702050815 DE2050815A1 (de) 1970-10-16 1970-10-16 Neue 2-(5-Nitro-2-furyl)-thieno eckige Klammer auf 3,2-d eckige Klammer zu pyrimidine
DE19702050816 DE2050816A1 (de) 1970-10-16 1970-10-16 Neue 2-(Nitro-2-furyl>thieno eckige Klammer auf 3,2-d eckige Klammer zu pyrimidine

Publications (1)

Publication Number Publication Date
GB1321316A true GB1321316A (en) 1973-06-27

Family

ID=27430978

Family Applications (1)

Application Number Title Priority Date Filing Date
GB5614670A Expired GB1321316A (en) 1969-11-26 1970-11-25 Nitrofuryl-thienopyrimidines

Country Status (13)

Country Link
US (1) US3661908A (enExample)
BE (1) BE759493A (enExample)
BG (2) BG17799A3 (enExample)
CA (1) CA926865A (enExample)
CH (3) CH559210A5 (enExample)
DK (1) DK128781B (enExample)
FR (1) FR2073416B1 (enExample)
GB (1) GB1321316A (enExample)
IE (1) IE34765B1 (enExample)
IL (1) IL35729A (enExample)
NL (1) NL7017210A (enExample)
NO (1) NO129954B (enExample)
SE (1) SE377938B (enExample)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3932642A (en) * 1971-04-10 1976-01-13 Boehringer Ingelheim Gmbh Biocidal compositions containing a 2- (5'-nitro-2'-furyl)-thieno(2,3-d) pyrimidine and methods of use
US6187777B1 (en) 1998-02-06 2001-02-13 Amgen Inc. Compounds and methods which modulate feeding behavior and related diseases
US6608053B2 (en) * 2000-04-27 2003-08-19 Yamanouchi Pharmaceutical Co., Ltd. Fused heteroaryl derivatives
US20040138238A1 (en) * 2002-08-08 2004-07-15 Dhanoa Dale S. Substituted aminopyrimidine compounds as neurokinin antagonists
GB0423653D0 (en) * 2004-10-25 2004-11-24 Piramed Ltd Pharmaceutical compounds
PT2041139E (pt) * 2006-04-26 2012-01-13 Hoffmann La Roche Compostos farmacêuticos
MX2008013583A (es) 2006-04-26 2008-10-31 Genentech Inc Compuestos del inhibidor de fosfoinositido 3-cinasa y composiciones farmaceuticas que los contienen.
UA95799C2 (en) 2006-04-26 2011-09-12 Ф. Хоффманн-Ля Рош Аг Pharmaceutical compounds
WO2008073785A2 (en) * 2006-12-07 2008-06-19 Genentech, Inc. Phosphoinositide 3-kinase inhibitor compounds and methods of use
AR064155A1 (es) * 2006-12-07 2009-03-18 Piramed Ltd Compuestos de inhibidores de fosfoinositido-3 quinasa y metodos de uso
JP5539190B2 (ja) * 2007-06-12 2014-07-02 エフ．ホフマン−ラ ロシュ アーゲー チアゾロピリミジン類及びホスファチジルイノシトール−３キナーゼのインヒビターとしてのそれらの使用
ES2399774T3 (es) * 2007-09-24 2013-04-03 Genentech, Inc. Compuestos de tiazolopirimidina inhibidores de PI3K y métodos de uso
CA2701292C (en) * 2007-10-25 2015-03-24 Genentech, Inc. Process for making thienopyrimidine compounds
GB0721095D0 (en) * 2007-10-26 2007-12-05 Piramed Ltd Pharmaceutical compounds
CA2753285A1 (en) 2009-03-12 2010-09-16 Genentech, Inc. Combinations of phosphoinositide 3-kinase inhibitor compounds and chemotherapeutic agents for the treatment of hematopoietic malignancies
CA2761445A1 (en) * 2009-05-27 2010-12-02 Genentech, Inc. Bicyclic pyrimidine pi3k inhibitor compounds selective for p110 delta, and methods of use
EP2451811A1 (en) * 2009-05-27 2012-05-16 F. Hoffmann-La Roche AG Bicyclic indole-pyrimidine pi3k inhibitor compounds selective for p110 delta, and methods of use
PE20121816A1 (es) * 2009-10-12 2013-01-02 Hoffmann La Roche Combinaciones de un inhibidor de pi3k y un inhibidor de mek
KR20130058672A (ko) 2010-04-16 2013-06-04 제넨테크, 인크. ＰＩ3Ｋ/ＡＫＴ 키나제 경로 억제제 효능에 대한 예측 바이오마커로서의 ＦＯＸＯ３ａ
US20140004209A1 (en) 2010-12-22 2014-01-02 Genentech, Inc. Autophagy inducer and inhibitor combination therapy for the treatment of neoplasms
JP6669500B2 (ja) 2013-02-25 2020-03-18 ジェネンテック， インコーポレイテッド 薬物耐性ａｋｔ変異体を検出し治療するための方法及び組成物

Also Published As

Publication number Publication date
NL7017210A (enExample) 1971-05-28
IL35729A (en) 1974-01-14
FR2073416B1 (enExample) 1975-04-18
US3661908A (en) 1972-05-09
BG17800A3 (bg) 1973-12-25
NO129954B (enExample) 1974-06-17
FR2073416A1 (enExample) 1971-10-01
CH559210A5 (enExample) 1975-02-28
CH567029A5 (enExample) 1975-09-30
CH568324A5 (enExample) 1975-10-31
DK128781B (da) 1974-07-01
SE377938B (enExample) 1975-08-04
IL35729A0 (en) 1971-01-28
IE34765B1 (en) 1975-08-06
BG17799A3 (bg) 1973-12-25
BE759493A (fr) 1971-05-25
IE34765L (en) 1971-05-26
CA926865A (en) 1973-05-22

Similar Documents

Publication Publication Date Title
GB1321316A (en) Nitrofuryl-thienopyrimidines
IL81483A0 (en) Piperazine derivatives and pharmaceutical compositions containing them
ATE60761T1 (de) Chinazolinderivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen.
GB1449100A (en) Pyrimidine derivatives processes for their preparation and their use in pharmaceutical compositions
DE68925223D1 (de) 3-Alkenyl-1-azabicyclo(3.2.0)hept-2-en-2-carbonsäure-Verbindungen
ES2073398T3 (es) Nuevos derivados substituidos del acido bencilideno- y cinamilideno-malonico con actividad como inhibidores de la proliferacion celular.
DK499282A (da) Heterocykliske forbindelser samt fremgangsmaade til fremstilling heraf
GB1287659A (en) Pyrimidinylpyrazole derivatives
ES8306753A1 (es) "procedimiento para la preparacion de nuevos derivados de azepina".
IL64647A (en) 2,8-disubstituted-4-thiomorpholino-pyrimido(5,4-d)pyrimidine derivatives,their preparation and pharmaceutical compositions containing them
GB901749A (en) New 2-substituted pyrimidines
GB1496787A (en) Heteroalkylthioalkyl amidine derivatives
GB1087174A (en) Piperidine derivatives
GB1364294A (en) 2-styrylquinazoline compounds
ES8707231A1 (es) Procedimiento para preparar nuevos derivados de la quinoleina y sus sales complementarias acidas
ES339432A1 (es) Un procedimiento para la obtencion de nuevas tetrahidro- quinazolinas sustituidas por halogenos.
ES385772A1 (es) Procedimiento para la preparacion de nuevas 2-(5-nitro-2- furil)-tieno (3,2-d) pirimidinas.
ATE78032T1 (de) 2-pyridylessigsaeurederivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen.
GB1333311A (en) N-bridged bicyclic heteroaromatic compounds
GB1185039A (en) Pyrimidine Derivatives and Compositions containing them
GB1254270A (en) Benzoxazepine derivatives
GB933968A (en) New phthalimide derivatives
GR3002560T3 (en) 2-selenomethyl-1, 4-dihydropyridines, a process for the preparation thereof and pharmaceutical compositions containing them
ES317320A1 (es) Procedimiento para la preparaciën de nuevos derivados de 5-nitro-furfurol
GB1229519A (enExample)

Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PLNP Patent lapsed through nonpayment of renewal fees