GB1310656A - Process for the manufacture of peptides - Google Patents
Process for the manufacture of peptidesInfo
- Publication number
- GB1310656A GB1310656A GB4470171A GB4470171A GB1310656A GB 1310656 A GB1310656 A GB 1310656A GB 4470171 A GB4470171 A GB 4470171A GB 4470171 A GB4470171 A GB 4470171A GB 1310656 A GB1310656 A GB 1310656A
- Authority
- GB
- United Kingdom
- Prior art keywords
- acid
- peptide
- ester
- polymer
- copolymerizate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 4
- 238000004519 manufacturing process Methods 0.000 title 1
- 102000004196 processed proteins & peptides Human genes 0.000 title 1
- 229920000642 polymer Polymers 0.000 abstract 4
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 abstract 3
- 239000002202 Polyethylene glycol Substances 0.000 abstract 2
- 150000001413 amino acids Chemical class 0.000 abstract 2
- 229920001223 polyethylene glycol Polymers 0.000 abstract 2
- KDYFGRWQOYBRFD-UHFFFAOYSA-N succinic acid Chemical compound OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 abstract 2
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 abstract 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 abstract 1
- HRPVXLWXLXDGHG-UHFFFAOYSA-N Acrylamide Chemical compound NC(=O)C=C HRPVXLWXLXDGHG-UHFFFAOYSA-N 0.000 abstract 1
- 101000653791 Bos taurus Protein S100-A12 Proteins 0.000 abstract 1
- QOSSAOTZNIDXMA-UHFFFAOYSA-N Dicylcohexylcarbodiimide Chemical compound C1CCCCC1N=C=NC1CCCCC1 QOSSAOTZNIDXMA-UHFFFAOYSA-N 0.000 abstract 1
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 abstract 1
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N Phenol Chemical compound OC1=CC=CC=C1 ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 abstract 1
- XTXRWKRVRITETP-UHFFFAOYSA-N Vinyl acetate Chemical compound CC(=O)OC=C XTXRWKRVRITETP-UHFFFAOYSA-N 0.000 abstract 1
- DFNSLURZCFNCKW-UHFFFAOYSA-N [N+](=O)([O-])C1=CC=C(C=C1)OC(C(CC(=O)OC1=CC=C(C=C1)[N+](=O)[O-])I)=O Chemical compound [N+](=O)([O-])C1=CC=C(C=C1)OC(C(CC(=O)OC1=CC=C(C=C1)[N+](=O)[O-])I)=O DFNSLURZCFNCKW-UHFFFAOYSA-N 0.000 abstract 1
- ZLNCGIAXVWNFRX-UHFFFAOYSA-N [N+](=O)([O-])C1=CC=C(C=C1)OC(C=C/C(=O)OC1=CC=C(C=C1)[N+](=O)[O-])=O Chemical compound [N+](=O)([O-])C1=CC=C(C=C1)OC(C=C/C(=O)OC1=CC=C(C=C1)[N+](=O)[O-])=O ZLNCGIAXVWNFRX-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 229910001854 alkali hydroxide Inorganic materials 0.000 abstract 1
- 150000008044 alkali metal hydroxides Chemical class 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 238000004440 column chromatography Methods 0.000 abstract 1
- 230000008878 coupling Effects 0.000 abstract 1
- 238000010168 coupling process Methods 0.000 abstract 1
- 238000005859 coupling reaction Methods 0.000 abstract 1
- 238000000502 dialysis Methods 0.000 abstract 1
- 125000004185 ester group Chemical group 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 238000005374 membrane filtration Methods 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
- 239000001384 succinic acid Substances 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
- C07K1/042—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers characterised by the nature of the carrier
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2047413A DE2047413C3 (de) | 1970-09-26 | 1970-09-26 | Verfahren zur Herstellung von Peptiden in homogener Phase |
Publications (1)
Publication Number | Publication Date |
---|---|
GB1310656A true GB1310656A (en) | 1973-03-21 |
Family
ID=5783460
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB4470171A Expired GB1310656A (en) | 1970-09-26 | 1971-09-24 | Process for the manufacture of peptides |
Country Status (11)
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5183B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1973-03-07 | 1976-01-05 | ||
FR2419278A1 (fr) * | 1978-03-10 | 1979-10-05 | Pierce Chemical Co | Procede de synthese de chaines peptidiques |
DE2930542A1 (de) * | 1979-07-27 | 1981-02-12 | Hoechst Ag | Neue insulinderivate und verfahren zu ihrer herstellung |
DK608589D0 (da) * | 1989-12-01 | 1989-12-01 | Holm Arne | Kemisk fremgangsmaade |
US5824784A (en) * | 1994-10-12 | 1998-10-20 | Amgen Inc. | N-terminally chemically modified protein compositions and methods |
GB0814519D0 (en) | 2008-08-08 | 2008-09-17 | Imp Innovations Ltd | Process |
GB0820865D0 (en) * | 2008-11-14 | 2008-12-24 | Membrane Extraction Tech Ltd | Degradable supports for tide synthesis |
GB201413954D0 (en) | 2014-08-06 | 2014-09-17 | Imp Innovations Ltd | Process for preparing polymers |
-
1970
- 1970-09-26 DE DE2047413A patent/DE2047413C3/de not_active Expired
-
1971
- 1971-09-07 CH CH1309971A patent/CH567458A5/xx not_active IP Right Cessation
- 1971-09-13 IL IL37698A patent/IL37698A/xx unknown
- 1971-09-17 US US00181609A patent/US3772264A/en not_active Expired - Lifetime
- 1971-09-24 GB GB4470171A patent/GB1310656A/en not_active Expired
- 1971-09-24 SE SE7112135A patent/SE398347B/xx unknown
- 1971-09-24 CA CA123,614A patent/CA1000271A/en not_active Expired
- 1971-09-24 FR FR7134440A patent/FR2108520A5/fr not_active Expired
- 1971-09-24 BE BE773013A patent/BE773013A/xx unknown
- 1971-09-24 NL NL7113179A patent/NL7113179A/xx not_active Application Discontinuation
- 1971-09-24 SU SU1700240A patent/SU454736A3/ru active
Also Published As
Publication number | Publication date |
---|---|
IL37698A (en) | 1975-04-25 |
BE773013A (fr) | 1972-03-24 |
CA1000271A (en) | 1976-11-23 |
DE2047413C3 (de) | 1980-05-29 |
DE2047413B2 (de) | 1979-09-06 |
NL7113179A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1972-03-28 |
CH567458A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1975-10-15 |
DE2047413A1 (de) | 1972-03-30 |
SU454736A3 (ru) | 1974-12-25 |
FR2108520A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1972-05-19 |
IL37698A0 (en) | 1971-11-29 |
US3772264A (en) | 1973-11-13 |
SE398347B (sv) | 1977-12-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PS | Patent sealed [section 19, patents act 1949] | ||
PCNP | Patent ceased through non-payment of renewal fee |