GB1259842A - Salts of acylamino-alkyl-benzenesulphonyl-ureas with anion exchangers and process for preparing them - Google Patents

Salts of acylamino-alkyl-benzenesulphonyl-ureas with anion exchangers and process for preparing them

Info

Publication number
GB1259842A
GB1259842A GB16625/69A GB1662569A GB1259842A GB 1259842 A GB1259842 A GB 1259842A GB 16625/69 A GB16625/69 A GB 16625/69A GB 1662569 A GB1662569 A GB 1662569A GB 1259842 A GB1259842 A GB 1259842A
Authority
GB
United Kingdom
Prior art keywords
benzenesulphonyl
march
ureas
acylamino
salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB16625/69A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Farbwerke Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19681768097 external-priority patent/DE1768097A1/en
Priority claimed from DE19691911806 external-priority patent/DE1911806A1/en
Application filed by Hoechst AG, Farbwerke Hoechst AG filed Critical Hoechst AG
Publication of GB1259842A publication Critical patent/GB1259842A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • A61K47/585—Ion exchange resins, e.g. polystyrene sulfonic acid resin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

1,259,842. Hypoglycemic compositions. FARBWERKE HOECHST A.G. 31 March, 1969 [30 March, 1968; 8 March, 1969], No. 16625/69. Heading A5B. [Also in Division C3] A pharmaceutical composition having hypoglycemic properties comprises a salt of a benzamoloalkyl-benzenesulphonyl-urea of formula: where Z is -H, -CH 3 , -OCH 3 , -F, -Cl or -Br; n is 2 or 3; and R is a cyclo-pentyl, -hexyl, or -heptyl, 3-methyl-cyclopentyl or 4-methylcyclohexyl groups, with an anion exchanger resin e.g. polystyrene containing quaternary ammonium groups e.g. trimethylbenzyl-ammonium or dimethyl-ethanolbenzyl-ammonium groups and a pharmaceutically suitable carrier.
GB16625/69A 1968-03-30 1969-03-31 Salts of acylamino-alkyl-benzenesulphonyl-ureas with anion exchangers and process for preparing them Expired GB1259842A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19681768097 DE1768097A1 (en) 1968-03-30 1968-03-30 Salts of N- [4- (ss- (2-methoxy-5-chlorobenzamido) -aethyl) -benzenesulfonyl] -N'-cyclohexylurea with anion exchangers
DE19691911806 DE1911806A1 (en) 1969-03-08 1969-03-08 Anion-exchange salts of benzaminoalkyl-benzenesulphonyl urea - hypoglycermic

Publications (1)

Publication Number Publication Date
GB1259842A true GB1259842A (en) 1972-01-12

Family

ID=25755491

Family Applications (1)

Application Number Title Priority Date Filing Date
GB16625/69A Expired GB1259842A (en) 1968-03-30 1969-03-31 Salts of acylamino-alkyl-benzenesulphonyl-ureas with anion exchangers and process for preparing them

Country Status (11)

Country Link
AT (1) AT288419B (en)
BE (1) BE730791A (en)
CA (1) CA936096A (en)
CH (1) CH519476A (en)
DK (1) DK127974B (en)
ES (1) ES365434A1 (en)
FR (1) FR2005190A1 (en)
GB (1) GB1259842A (en)
IE (1) IE32681B1 (en)
IL (1) IL31923A (en)
NL (1) NL6904843A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2134529A (en) * 1983-01-12 1984-08-15 Ciba Geigy Ag Drug-resin complex

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES384463A1 (en) * 1970-09-23 1973-10-01 Uriach & Cia Sa J Cyclopentyl urea and process for its production

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1413851A (en) * 1957-05-06 1965-10-15 Clinical Products Ltd Process for the manufacture of compounds intended to slowly and uniformly release an active substance in either an acidic or a basic medium
GB999710A (en) * 1963-02-20 1965-07-28 Upjohn Co Hypoglycemic sulphonyl urea medicaments

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2134529A (en) * 1983-01-12 1984-08-15 Ciba Geigy Ag Drug-resin complex

Also Published As

Publication number Publication date
CH519476A (en) 1972-02-29
NL6904843A (en) 1969-10-02
BE730791A (en) 1969-09-30
ES365434A1 (en) 1971-03-16
IE32681L (en) 1969-09-30
CA936096A (en) 1973-10-30
IE32681B1 (en) 1973-10-31
AT288419B (en) 1971-03-10
DK127974B (en) 1974-02-11
IL31923A (en) 1972-12-29
FR2005190A1 (en) 1969-12-05

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Legal Events

Date Code Title Description
PS Patent sealed
PLNP Patent lapsed through nonpayment of renewal fees