IE32681B1 - Salts of acylamino-alkyl-benzenesulphonyl-ureas with anion exchangers and process for preparing them - Google Patents

Salts of acylamino-alkyl-benzenesulphonyl-ureas with anion exchangers and process for preparing them

Info

Publication number
IE32681B1
IE32681B1 IE427/69A IE42769A IE32681B1 IE 32681 B1 IE32681 B1 IE 32681B1 IE 427/69 A IE427/69 A IE 427/69A IE 42769 A IE42769 A IE 42769A IE 32681 B1 IE32681 B1 IE 32681B1
Authority
IE
Ireland
Prior art keywords
benzenesulphonyl
march
ureas
acylamino
salts
Prior art date
Application number
IE427/69A
Other versions
IE32681L (en
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19681768097 external-priority patent/DE1768097A1/en
Priority claimed from DE19691911806 external-priority patent/DE1911806A1/en
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of IE32681L publication Critical patent/IE32681L/en
Publication of IE32681B1 publication Critical patent/IE32681B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • A61K47/585—Ion exchange resins, e.g. polystyrene sulfonic acid resin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

1,259,842. Hypoglycemic compositions. FARBWERKE HOECHST A.G. 31 March, 1969 [30 March, 1968; 8 March, 1969], No. 16625/69. Heading A5B. [Also in Division C3] A pharmaceutical composition having hypoglycemic properties comprises a salt of a benzamoloalkyl-benzenesulphonyl-urea of formula: where Z is -H, -CH 3 , -OCH 3 , -F, -Cl or -Br; n is 2 or 3; and R is a cyclo-pentyl, -hexyl, or -heptyl, 3-methyl-cyclopentyl or 4-methylcyclohexyl groups, with an anion exchanger resin e.g. polystyrene containing quaternary ammonium groups e.g. trimethylbenzyl-ammonium or dimethyl-ethanolbenzyl-ammonium groups and a pharmaceutically suitable carrier. [GB1259842A]
IE427/69A 1968-03-30 1969-03-28 Salts of acylamino-alkyl-benzenesulphonyl-ureas with anion exchangers and process for preparing them IE32681B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19681768097 DE1768097A1 (en) 1968-03-30 1968-03-30 Salts of N- [4- (ss- (2-methoxy-5-chlorobenzamido) -aethyl) -benzenesulfonyl] -N'-cyclohexylurea with anion exchangers
DE19691911806 DE1911806A1 (en) 1969-03-08 1969-03-08 Anion-exchange salts of benzaminoalkyl-benzenesulphonyl urea - hypoglycermic

Publications (2)

Publication Number Publication Date
IE32681L IE32681L (en) 1969-09-30
IE32681B1 true IE32681B1 (en) 1973-10-31

Family

ID=25755491

Family Applications (1)

Application Number Title Priority Date Filing Date
IE427/69A IE32681B1 (en) 1968-03-30 1969-03-28 Salts of acylamino-alkyl-benzenesulphonyl-ureas with anion exchangers and process for preparing them

Country Status (11)

Country Link
AT (1) AT288419B (en)
BE (1) BE730791A (en)
CA (1) CA936096A (en)
CH (1) CH519476A (en)
DK (1) DK127974B (en)
ES (1) ES365434A1 (en)
FR (1) FR2005190A1 (en)
GB (1) GB1259842A (en)
IE (1) IE32681B1 (en)
IL (1) IL31923A (en)
NL (1) NL6904843A (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES384463A1 (en) * 1970-09-23 1973-10-01 Uriach & Cia Sa J Cyclopentyl urea and process for its production
CH655507B (en) * 1983-01-12 1986-04-30

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1413851A (en) * 1957-05-06 1965-10-15 Clinical Products Ltd Process for the manufacture of compounds intended to slowly and uniformly release an active substance in either an acidic or a basic medium
GB999710A (en) * 1963-02-20 1965-07-28 Upjohn Co Hypoglycemic sulphonyl urea medicaments

Also Published As

Publication number Publication date
CH519476A (en) 1972-02-29
NL6904843A (en) 1969-10-02
GB1259842A (en) 1972-01-12
BE730791A (en) 1969-09-30
ES365434A1 (en) 1971-03-16
IE32681L (en) 1969-09-30
CA936096A (en) 1973-10-30
AT288419B (en) 1971-03-10
DK127974B (en) 1974-02-11
IL31923A (en) 1972-12-29
FR2005190A1 (en) 1969-12-05

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