ES311586A1 - A procedure to prepare a bis-biguanida. (Machine-translation by Google Translate, not legally binding) - Google Patents

A procedure to prepare a bis-biguanida. (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES311586A1
ES311586A1 ES0311586A ES311586A ES311586A1 ES 311586 A1 ES311586 A1 ES 311586A1 ES 0311586 A ES0311586 A ES 0311586A ES 311586 A ES311586 A ES 311586A ES 311586 A1 ES311586 A1 ES 311586A1
Authority
ES
Spain
Prior art keywords
formula
see
bis
carbon atoms
translation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES0311586A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
STWB Inc
Original Assignee
Sterling Drug Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Drug Inc filed Critical Sterling Drug Inc
Publication of ES311586A1 publication Critical patent/ES311586A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
    • C07C323/43—Y being a hetero atom
    • C07C323/44—X or Y being nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/43—Guanidines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/005—Antimicrobial preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/12—Preparations containing hair conditioners
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/24—Y being a hetero atom
    • C07C279/26—X and Y being nitrogen atoms, i.e. biguanides
    • C07C279/265—X and Y being nitrogen atoms, i.e. biguanides containing two or more biguanide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C317/32—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C317/34—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring
    • C07C317/38—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring with the nitrogen atom of at least one amino group being part of any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylaminosulfones
    • C07C317/42—Y being a hetero atom

Abstract

A process for preparing a bis-biguanide of formula I (see memory), in which A is an alcohol with 2 to 12 carbon atoms with valence bonds attached to different carbon atoms, - (CH2) mY- (CH2) n- in which m and n represent, each one, an integer between 2 and 6 and Y is O or S; ** (See formula) ** where Z and Z 'are alcohol with 1 to 3 carbon atoms, ** (See formula) ** where Q is O, S, SO, SO2, R is an alkylcarbon with 6 to 16 carbon atoms or an alkyl-Y-alkyl alcohol, in which Y is O or S; R 'is H or lower alkyl; and x is 2, comprising: (a) reacting a bridged-bis (3-cyanoguanidine) of formula II (see memory), or an amidino-o-alkyl urea equivalent thereto, with an amine of formula III (see memory) in the form of addition salt of acid, or (b) reacting an alcoholyl diamine of formula IV (see specification) in its acid addition salt form with a 3-cyanoguanidine of formula V (see memory) or an amidino-o-alkylurea equivalent thereof, and, if You want to obtain the product in the form of a free base or in the form of a salt from it. (Machine-translation by Google Translate, not legally binding)
ES0311586A 1964-04-09 1965-04-08 A procedure to prepare a bis-biguanida. (Machine-translation by Google Translate, not legally binding) Expired ES311586A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US35861464A 1964-04-09 1964-04-09

Publications (1)

Publication Number Publication Date
ES311586A1 true ES311586A1 (en) 1965-07-16

Family

ID=23410360

Family Applications (1)

Application Number Title Priority Date Filing Date
ES0311586A Expired ES311586A1 (en) 1964-04-09 1965-04-08 A procedure to prepare a bis-biguanida. (Machine-translation by Google Translate, not legally binding)

Country Status (7)

Country Link
BR (1) BR6568736D0 (en)
CH (1) CH486429A (en)
DE (1) DE1493210B2 (en)
DO (1) DOP1965001173A (en)
ES (1) ES311586A1 (en)
FR (1) FR1463818A (en)
GB (1) GB1095902A (en)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3562385A (en) * 1968-12-23 1971-02-09 Merck & Co Inc Dental antiplaque and anticalculus compositions
IL39245A (en) * 1971-04-21 1974-12-31 Murphy Chemical Ltd Diguanidino alkanes and fungicidal compositions containing them
BE793229A (en) * 1971-12-23 1973-06-22 Merck & Co Inc GUANIDINE DERIVATIVES WITH ANTI-ACNE ACTION
NO135634C (en) * 1972-03-16 1977-05-04 Farmaceutisk Ind As
IE37842B1 (en) * 1972-06-30 1977-10-26 Procter & Gamble Oral compositions for plaque caries and calculus retardation with reduced staining tendencies
GB1365030A (en) * 1972-11-30 1974-08-29 Merck & Co Inc Oral compositions
DE2651467A1 (en) * 1976-11-11 1978-05-18 Bayer Ag SUBSTITUTED O-PHENYLENE DIAMINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS MEDICINAL PRODUCTS
GB8312661D0 (en) * 1983-05-09 1983-06-15 Ici Plc Bisbiguanide derivatives
GB8312663D0 (en) * 1983-05-09 1983-06-15 Ici Plc Bisbiguanide compounds
GB8312662D0 (en) * 1983-05-09 1983-06-15 Ici Plc Polyether bisbiguanide
GB8312665D0 (en) * 1983-05-09 1983-06-15 Ici Plc 4,4'-alkylenedipiperidine derivatives
GB8327561D0 (en) * 1983-10-14 1983-11-16 Ici Plc Contraceptive methods
GB8327562D0 (en) * 1983-10-14 1983-11-16 Ici Plc Contraceptive methods
US4567174A (en) * 1984-05-07 1986-01-28 Imperial Chemical Industries Plc Bis(1-substituted biguanide) derivatives
GB8810412D0 (en) * 1988-05-03 1988-06-08 Ici Plc Hard tissue surface treatment
CA2064664C (en) * 1991-04-05 2000-01-11 Hiroshi Ishikawa Biguanide derivatives, manufacturing method thereof, and disinfectants containing the derivatives
BR9713017A (en) * 1996-11-13 2000-01-25 Baush & Lombincorporated Method for cleaning and / or disinfecting flexible contact lenses
US5965088A (en) * 1997-10-23 1999-10-12 Lever; Andrea M. Method for providing rapid disinfection of contact lenses
AT411060B (en) * 2000-10-23 2003-09-25 P O C Oil Industry Technology New polymeric guanidine derivatives, used as disinfectant in (veterinary) medicine, waste liquor purification or domestic or trade application, are polycondensates of diamine with oxyalkylene chain and guanidine acid addition salt
FR2841778B1 (en) * 2002-07-05 2004-10-01 Oreal USE OF A POLYGUANIDINE-DERIVED COMPOUND IN A COLOR TREATMENT
WO2008013555A1 (en) * 2006-07-26 2008-01-31 Watervisions International, Inc. Broad spectrum antimicrobial purification materials and methods for purifying fluids
AT513858B1 (en) 2013-01-25 2014-08-15 Sealife Pharma Gmbh New bioactive polymers
ES2881278T3 (en) 2013-04-26 2021-11-29 Biointeractions Ltd Bioactive coatings
USRE49528E1 (en) 2013-04-26 2023-05-16 Biointeractions Ltd. Bioactive coatings
AT516070B1 (en) 2014-07-31 2016-08-15 Sealife Pharma Gmbh Process for the preparation of polyguanidines
US10004702B2 (en) 2014-10-10 2018-06-26 Lead Discovery Siena S.R.L. Linear guanidine derivatives, methods of preparation and uses thereof
EP3524055A1 (en) 2018-02-08 2019-08-14 BCSK Biocid GmbH Antibacterial and spermicidal lubricant

Also Published As

Publication number Publication date
DE1493210B2 (en) 1976-04-22
GB1095902A (en) 1967-12-20
BR6568736D0 (en) 1973-08-14
FR1463818A (en) 1966-07-22
DE1493210A1 (en) 1969-04-03
DOP1965001173A (en) 1971-05-30
CH486429A (en) 1970-02-28

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