ES405106A1 - Substituted pyrrolidines - Google Patents

Substituted pyrrolidines

Info

Publication number
ES405106A1
ES405106A1 ES405106A ES405106A ES405106A1 ES 405106 A1 ES405106 A1 ES 405106A1 ES 405106 A ES405106 A ES 405106A ES 405106 A ES405106 A ES 405106A ES 405106 A1 ES405106 A1 ES 405106A1
Authority
ES
Spain
Prior art keywords
formula
group
compound
benzyl
toxic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES405106A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceuticals Inc
Original Assignee
McNeilab Inc
McNeil Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by McNeilab Inc, McNeil Laboratories Inc filed Critical McNeilab Inc
Publication of ES405106A1 publication Critical patent/ES405106A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)

Abstract

A procedure for the preparation of a compound selected from the group consisting of a 2-imino-pyrrolidine of the formula: ** (See formula) ** where R1 is a member selected from the group consisting of lower alkyl and benzyl; R2 is a member selected from the group consisting of hydrogen and methyl; R3 is lower alkoxy and R4 is lower alkoxy and the non-toxic and therapeutically active acid addition salts thereof, provided that, when R1 is benzyl, R2 is methyl, the process of which is characterized by reacting a compound of formula ** (See formula) ** with a compound of formula ** (See formula) ** in a suitable solvent and, if desired, prepare an addition salt, with acid of the obtained product, non-toxic and therapeutically active. (Machine-translation by Google Translate, not legally binding)
ES405106A 1971-07-23 1972-07-22 Substituted pyrrolidines Expired ES405106A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US16586271A 1971-07-23 1971-07-23

Publications (1)

Publication Number Publication Date
ES405106A1 true ES405106A1 (en) 1975-07-16

Family

ID=22600787

Family Applications (1)

Application Number Title Priority Date Filing Date
ES405106A Expired ES405106A1 (en) 1971-07-23 1972-07-22 Substituted pyrrolidines

Country Status (14)

Country Link
JP (1) JPS5719103B1 (en)
AT (1) AT313269B (en)
AU (1) AU465195B2 (en)
BE (1) BE786590A (en)
CA (1) CA961497A (en)
CH (1) CH572908A5 (en)
DE (1) DE2235683A1 (en)
ES (1) ES405106A1 (en)
FR (1) FR2150711B1 (en)
GB (1) GB1379062A (en)
IL (1) IL39966A (en)
NL (1) NL7210140A (en)
SE (1) SE385880B (en)
ZA (1) ZA725040B (en)

Also Published As

Publication number Publication date
BE786590A (en) 1973-01-22
AU4478772A (en) 1974-01-24
GB1379062A (en) 1975-01-02
IL39966A (en) 1975-04-25
CA961497A (en) 1975-01-21
JPS5719103B1 (en) 1982-04-20
FR2150711B1 (en) 1975-10-31
FR2150711A1 (en) 1973-04-13
SE385880B (en) 1976-07-26
ZA725040B (en) 1974-02-27
AU465195B2 (en) 1975-09-18
AT313269B (en) 1974-02-11
NL7210140A (en) 1973-01-25
IL39966A0 (en) 1972-09-28
DE2235683A1 (en) 1973-02-08
CH572908A5 (en) 1976-02-27

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