ES376507A1 - Process for producing an anti-depressant effect with piperazine quinolines - Google Patents

Process for producing an anti-depressant effect with piperazine quinolines

Info

Publication number
ES376507A1
ES376507A1 ES376507A ES376507A ES376507A1 ES 376507 A1 ES376507 A1 ES 376507A1 ES 376507 A ES376507 A ES 376507A ES 376507 A ES376507 A ES 376507A ES 376507 A1 ES376507 A1 ES 376507A1
Authority
ES
Spain
Prior art keywords
formula
piperazine
compound
quinolines
producing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES376507A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Corp
Original Assignee
Miles Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Miles Laboratories Inc filed Critical Miles Laboratories Inc
Publication of ES376507A1 publication Critical patent/ES376507A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A method of preparing an antidepressant composition based on piperazine and quinoline derivatives, comprising reacting the compound of the formula **(See formula)** with a compound of the formula **(See formula)** in a suitable solvent, whereby a compound of the formula is obtained: **(See formula)** where R is H or CH3; and mixing an effective amount of the resulting reaction product or pharmacologically acceptable non-toxic acid addition salts thereof, prepared according to known procedures, with a pharmaceutical carrier therefor. (Machine-translation by Google Translate, not legally binding)
ES376507A 1969-02-14 1970-02-12 Process for producing an anti-depressant effect with piperazine quinolines Expired ES376507A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US79950869A 1969-02-14 1969-02-14

Publications (1)

Publication Number Publication Date
ES376507A1 true ES376507A1 (en) 1972-07-01

Family

ID=25176090

Family Applications (1)

Application Number Title Priority Date Filing Date
ES376507A Expired ES376507A1 (en) 1969-02-14 1970-02-12 Process for producing an anti-depressant effect with piperazine quinolines

Country Status (5)

Country Link
US (1) US3629418A (en)
BR (1) BR7016716D0 (en)
CH (1) CH530408A (en)
DE (1) DE2006638A1 (en)
ES (1) ES376507A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4656174A (en) * 1982-07-24 1987-04-07 Pfizer Inc. Quinoline therapeutic agents
US6040448A (en) 1997-10-24 2000-03-21 Neurogen Corporation Certain 1-(2-naphthyl) and 1-(2-azanaphthyl)-4-(1-phenylmethyl) piperazines, dopamine receptor subtype specific ligands
DE69829989T2 (en) * 1997-10-24 2006-02-23 Neurogen Corp., Branford 1- (2-NAPHTHYL) AND 1- (2-AZANAPHTHYL) -4- (1-PHENYLMETHYL) PIPERAZINE AS DOPAMINE D4 SUBTYPE LIGANDS

Also Published As

Publication number Publication date
CH530408A (en) 1972-11-15
BR7016716D0 (en) 1973-04-12
US3629418A (en) 1971-12-21
DE2006638A1 (en) 1970-09-03

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