ES376507A1 - Process for producing an anti-depressant effect with piperazine quinolines - Google Patents
Process for producing an anti-depressant effect with piperazine quinolinesInfo
- Publication number
- ES376507A1 ES376507A1 ES376507A ES376507A ES376507A1 ES 376507 A1 ES376507 A1 ES 376507A1 ES 376507 A ES376507 A ES 376507A ES 376507 A ES376507 A ES 376507A ES 376507 A1 ES376507 A1 ES 376507A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- piperazine
- compound
- quinolines
- producing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
A method of preparing an antidepressant composition based on piperazine and quinoline derivatives, comprising reacting the compound of the formula **(See formula)** with a compound of the formula **(See formula)** in a suitable solvent, whereby a compound of the formula is obtained: **(See formula)** where R is H or CH3; and mixing an effective amount of the resulting reaction product or pharmacologically acceptable non-toxic acid addition salts thereof, prepared according to known procedures, with a pharmaceutical carrier therefor. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US79950869A | 1969-02-14 | 1969-02-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES376507A1 true ES376507A1 (en) | 1972-07-01 |
Family
ID=25176090
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES376507A Expired ES376507A1 (en) | 1969-02-14 | 1970-02-12 | Process for producing an anti-depressant effect with piperazine quinolines |
Country Status (5)
Country | Link |
---|---|
US (1) | US3629418A (en) |
BR (1) | BR7016716D0 (en) |
CH (1) | CH530408A (en) |
DE (1) | DE2006638A1 (en) |
ES (1) | ES376507A1 (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4656174A (en) * | 1982-07-24 | 1987-04-07 | Pfizer Inc. | Quinoline therapeutic agents |
US6040448A (en) | 1997-10-24 | 2000-03-21 | Neurogen Corporation | Certain 1-(2-naphthyl) and 1-(2-azanaphthyl)-4-(1-phenylmethyl) piperazines, dopamine receptor subtype specific ligands |
DE69829989T2 (en) * | 1997-10-24 | 2006-02-23 | Neurogen Corp., Branford | 1- (2-NAPHTHYL) AND 1- (2-AZANAPHTHYL) -4- (1-PHENYLMETHYL) PIPERAZINE AS DOPAMINE D4 SUBTYPE LIGANDS |
-
1969
- 1969-02-14 US US799508A patent/US3629418A/en not_active Expired - Lifetime
-
1970
- 1970-02-11 CH CH197870A patent/CH530408A/en not_active IP Right Cessation
- 1970-02-12 ES ES376507A patent/ES376507A1/en not_active Expired
- 1970-02-13 DE DE19702006638 patent/DE2006638A1/en active Pending
- 1970-02-13 BR BR216716/70A patent/BR7016716D0/en unknown
Also Published As
Publication number | Publication date |
---|---|
CH530408A (en) | 1972-11-15 |
BR7016716D0 (en) | 1973-04-12 |
US3629418A (en) | 1971-12-21 |
DE2006638A1 (en) | 1970-09-03 |
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