GB1256733A - - Google Patents
Info
- Publication number
- GB1256733A GB1256733A GB1256733DA GB1256733A GB 1256733 A GB1256733 A GB 1256733A GB 1256733D A GB1256733D A GB 1256733DA GB 1256733 A GB1256733 A GB 1256733A
- Authority
- GB
- United Kingdom
- Prior art keywords
- general formula
- derivative
- reaction
- halogen atom
- thionine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000006243 chemical reaction Methods 0.000 abstract 5
- 125000005843 halogen group Chemical group 0.000 abstract 4
- 150000000552 thionines Chemical class 0.000 abstract 4
- 239000002253 acid Substances 0.000 abstract 3
- 230000002378 acidificating effect Effects 0.000 abstract 3
- 230000003647 oxidation Effects 0.000 abstract 3
- 238000007254 oxidation reaction Methods 0.000 abstract 3
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 2
- 239000005864 Sulphur Substances 0.000 abstract 2
- 150000001450 anions Chemical class 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxide Chemical compound [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 125000001484 phenothiazinyl group Chemical class C1(=CC=CC=2SC3=CC=CC=C3NC12)* 0.000 abstract 2
- 150000004986 phenylenediamines Chemical class 0.000 abstract 2
- 239000000126 substance Substances 0.000 abstract 2
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 abstract 1
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 150000008044 alkali metal hydroxides Chemical class 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 1
- 229910052794 bromium Inorganic materials 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000026030 halogenation Effects 0.000 abstract 1
- 238000005658 halogenation reaction Methods 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
- C07D279/14—1,4-Thiazines; Hydrogenated 1,4-thiazines condensed with carbocyclic rings or ring systems
- C07D279/18—[b, e]-condensed with two six-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HUEE001491 | 1968-02-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1256733A true GB1256733A (enExample) | 1971-12-15 |
Family
ID=10995247
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1256733D Expired GB1256733A (enExample) | 1968-02-16 | 1969-02-05 |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US3641016A (enExample) |
| AT (1) | AT287732B (enExample) |
| BE (1) | BE728439A (enExample) |
| BR (1) | BR6906449D0 (enExample) |
| CH (1) | CH520160A (enExample) |
| CS (1) | CS157051B2 (enExample) |
| DE (1) | DE1906527C3 (enExample) |
| DK (1) | DK131628C (enExample) |
| FI (1) | FI50419C (enExample) |
| FR (1) | FR2002028A1 (enExample) |
| GB (1) | GB1256733A (enExample) |
| IL (1) | IL31550A (enExample) |
| NL (1) | NL6902424A (enExample) |
| PL (1) | PL72594B1 (enExample) |
| SE (1) | SE361480B (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116178987A (zh) * | 2023-03-02 | 2023-05-30 | 山东中康国创先进印染技术研究院有限公司 | 一种可用于对纺织品进行染色的蓝色系染料及其染色方法 |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1408734A (en) * | 1972-11-06 | 1975-10-01 | Misubishi Chemical Ind Ltd | Basic dyestuff mixtures |
| GB0113121D0 (en) * | 2001-05-30 | 2001-07-18 | Univ Leeds | Biologically active photosensitisers |
| US7368221B2 (en) * | 2002-06-17 | 2008-05-06 | Verification Technologies, Inc. | Changing light absorption by disruption of conjugation |
| US20080193873A1 (en) * | 2002-06-17 | 2008-08-14 | Verification Technologies, Inc. | Changing light absorption by disruption of conjugation |
| BRPI0416928A (pt) * | 2003-11-28 | 2007-01-16 | Photopharmica Ltd | desenvolvimento de derivados biologicamente ativos de azul de metileno |
| WO2006032879A2 (en) | 2004-09-23 | 2006-03-30 | Wista Laboratories Ltd. | Methods of chemical synthesis and purification of diaminophenothiazinium compounds including methylthioninium chloride (mtc) |
| US7220879B2 (en) | 2004-10-01 | 2007-05-22 | Rohm And Haas Company | Method for inhibiting polymerization of (meth)acrylic acid and its esters using an inhibitor and a process for making a compound useful as such an inhibitor |
| US7101997B2 (en) * | 2004-10-07 | 2006-09-05 | Honeywell International Inc. | Method for producing phenothiazinium compounds |
| CN104119294B (zh) * | 2006-03-29 | 2018-10-30 | 维斯塔实验室有限公司 | 3,7-二氨基-10h-吩噻嗪化合物的制备方法 |
| MY162313A (en) | 2006-07-11 | 2017-05-31 | Wista Lab Ltd | Methods of synthesis and/or purification of diaminophenothiazinium compounds |
| US9795242B2 (en) | 2013-02-14 | 2017-10-24 | Cirkul, Inc. | Additive delivery systems and containers |
| US10888826B2 (en) | 2014-11-21 | 2021-01-12 | Cirkul, Inc. | Adjustable additive cartridge systems and methods |
| CN107205565B (zh) | 2014-11-21 | 2020-07-03 | 塞考尔有限公司 | 可调节的添加剂套筒系统 |
| US12017191B2 (en) | 2017-03-06 | 2024-06-25 | Cirkul, Inc. | Adjustable additive delivery systems and dispensing closure valves for the same |
| EP3375777A1 (en) * | 2017-03-15 | 2018-09-19 | MIKROCHEM spol. s.r.o. | Method for preparation of 3,7-bis-(dimethylamino)-phenothiazin-5-ium chloride or bromide |
-
1969
- 1969-02-03 US US796216A patent/US3641016A/en not_active Expired - Lifetime
- 1969-02-04 IL IL31550A patent/IL31550A/en unknown
- 1969-02-05 GB GB1256733D patent/GB1256733A/en not_active Expired
- 1969-02-10 DE DE1906527A patent/DE1906527C3/de not_active Expired
- 1969-02-11 AT AT135169A patent/AT287732B/de not_active IP Right Cessation
- 1969-02-14 FR FR6903561A patent/FR2002028A1/fr not_active Withdrawn
- 1969-02-14 DK DK80669*#A patent/DK131628C/da active
- 1969-02-14 SE SE02078/69A patent/SE361480B/xx unknown
- 1969-02-14 FI FI690477A patent/FI50419C/fi active
- 1969-02-14 BE BE728439D patent/BE728439A/xx unknown
- 1969-02-14 CH CH229569A patent/CH520160A/de not_active IP Right Cessation
- 1969-02-14 BR BR206449/69A patent/BR6906449D0/pt unknown
- 1969-02-14 NL NL6902424A patent/NL6902424A/xx unknown
- 1969-02-15 PL PL1969131750A patent/PL72594B1/pl unknown
- 1969-02-17 CS CS105969A patent/CS157051B2/cs unknown
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN116178987A (zh) * | 2023-03-02 | 2023-05-30 | 山东中康国创先进印染技术研究院有限公司 | 一种可用于对纺织品进行染色的蓝色系染料及其染色方法 |
| CN116178987B (zh) * | 2023-03-02 | 2024-06-28 | 山东中康国创先进印染技术研究院有限公司 | 一种可用于对纺织品进行染色的蓝色系染料及其染色方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| IL31550A0 (en) | 1969-04-30 |
| DE1906527A1 (de) | 1969-12-04 |
| DE1906527C3 (de) | 1981-07-02 |
| SE361480B (enExample) | 1973-11-05 |
| PL72594B1 (enExample) | 1974-08-30 |
| IL31550A (en) | 1972-06-28 |
| CS157051B2 (enExample) | 1974-08-23 |
| FR2002028A1 (enExample) | 1969-10-03 |
| FI50419B (enExample) | 1975-12-01 |
| US3641016A (en) | 1972-02-08 |
| DK131628B (da) | 1975-08-11 |
| AT287732B (de) | 1971-02-10 |
| BE728439A (enExample) | 1969-07-16 |
| CH520160A (de) | 1972-03-15 |
| BR6906449D0 (pt) | 1973-01-16 |
| NL6902424A (enExample) | 1969-08-19 |
| DE1906527B2 (de) | 1980-11-06 |
| DK131628C (da) | 1976-02-16 |
| FI50419C (fi) | 1976-03-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] | ||
| PCNP | Patent ceased through non-payment of renewal fee |