GB1347433A - Acetophenone oxime derivatives and pharmaceutical preparations which contain the same - Google Patents

Acetophenone oxime derivatives and pharmaceutical preparations which contain the same

Info

Publication number
GB1347433A
GB1347433A GB2462572A GB2462572A GB1347433A GB 1347433 A GB1347433 A GB 1347433A GB 2462572 A GB2462572 A GB 2462572A GB 2462572 A GB2462572 A GB 2462572A GB 1347433 A GB1347433 A GB 1347433A
Authority
GB
United Kingdom
Prior art keywords
reaction
hydrogen
compound
oxime derivatives
contain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2462572A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Koninklijke Philips NV
Original Assignee
Philips Gloeilampenfabrieken NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Philips Gloeilampenfabrieken NV filed Critical Philips Gloeilampenfabrieken NV
Publication of GB1347433A publication Critical patent/GB1347433A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/15—Oximes (>C=N—O—); Hydrazines (>N—N<); Hydrazones (>N—N=) ; Imines (C—N=C)

Abstract

1347433 Acetophenone-oxime derivatives PHILIPS GLOEILAMPENFABRIEKEN NV 25 May 1972 [28 May 1971] 24625/72 Heading C2C Novel compounds I: in which Hal is bromine or chlorine and R is hydrogen or the group COR 1 where R 1 is hydrogen, C 1-11 alkyl, C 1-11 alkoxy or a group of Formula II: are prepared by (1) reaction of a 4-halogenated acetophenone with NH 2 -O-CH 2 .CH 2 -OR, (2) reaction of a compound V in which M is hydrogen or a metal with R 2 -CH 2 -CH 2 -OR in which R 2 is halogen or the tosyloxy group, (3) reaction of a compound VII: with ROH, (4) reaction of a compound I in which R is H with a compound R 3 -COR, in which R 3 is OH, halogen, C 1-4 alkoxy or R 1 -CO-O- with the proviso that when R 1 is hydrogen, R 3 is not R 1 -CO-O-, or (5) reaction of an alcohol of Formula I (R = H) with ethylene oxide. Compounds I show anti-inflammatory and analgesic activity and form with a suitable carrier a pharmaceutical preparation which may be administered orally, parenterally or rectally.
GB2462572A 1971-05-28 1972-05-25 Acetophenone oxime derivatives and pharmaceutical preparations which contain the same Expired GB1347433A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL7107360A NL7107360A (en) 1971-05-28 1971-05-28

Publications (1)

Publication Number Publication Date
GB1347433A true GB1347433A (en) 1974-02-27

Family

ID=19813272

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2462572A Expired GB1347433A (en) 1971-05-28 1972-05-25 Acetophenone oxime derivatives and pharmaceutical preparations which contain the same

Country Status (8)

Country Link
US (1) US3803235A (en)
BE (1) BE784076A (en)
CH (3) CH590828A5 (en)
DE (1) DE2225190C3 (en)
ES (1) ES403209A1 (en)
FR (1) FR2140047B1 (en)
GB (1) GB1347433A (en)
NL (1) NL7107360A (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR205682A1 (en) * 1970-06-11 1976-05-31 Philips Nv METHOD OF PRODUCTION OF AMINO-OXYACETIC (4-CHLORO-ALPHA-METHYLBENZYLIDEN) ESTER (2-DIMETHYLAMINOETHYL) ACID AND ITS ACID ADDITION SALTS FORMED WITH PHARMACOLOGICALLY ACCEPTABLE ACIDS
IT1110460B (en) * 1977-03-02 1985-12-23 Ciba Geigy Ag PRODUCTS THAT PROMOTE THE GROWTH OF PLANTS AND PRODUCTS THAT PROTECT PLANTS BASED ON BODY ETHERS AND BODY ESTERS THEIR PREPARATION AND USE
US4581060A (en) * 1977-03-02 1986-04-08 Ciba-Geigy Corporation Compositions, which promote plant growth and protect plants, based on oxime ethers and oxime esters
CH632130A5 (en) * 1977-03-02 1982-09-30 Ciba Geigy Ag Compositions on the basis of oxime ethers, oxime esters or oxime carbamates which are suitable in agriculture for crop protection
US4353735A (en) * 1978-08-31 1982-10-12 Ciba-Geigy Corporation Oxime derivatives for protecting plant crops
US4488900A (en) * 1978-08-31 1984-12-18 Ciba-Geigy Corporation Oxime derivatives for protecting plant crops
US4488898A (en) * 1978-08-31 1984-12-18 Ciba-Geigy Corporation Oxime derivatives for protecting plant crops
US4488899A (en) * 1978-08-31 1984-12-18 Ciba-Geigy Corporation Oxime derivatives for protecting plant crops
EP1925610A1 (en) * 2006-11-24 2008-05-28 Bayer CropScience AG Production process of 2-aminooxyethanol

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3040097A (en) * 1959-04-06 1962-06-19 Purdue Research Foundation Beta-hydroxy alkyl ethers of oximes and production thereof

Also Published As

Publication number Publication date
ES403209A1 (en) 1976-01-16
US3803235A (en) 1974-04-09
DE2225190B2 (en) 1980-10-16
DE2225190A1 (en) 1973-01-11
CH590828A5 (en) 1977-08-31
BE784076A (en) 1972-11-27
DE2225190C3 (en) 1982-01-21
NL7107360A (en) 1972-11-30
CH590829A5 (en) 1977-08-31
FR2140047A1 (en) 1973-01-12
CH587234A5 (en) 1977-04-29
FR2140047B1 (en) 1975-06-20

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
732 Registration of transactions, instruments or events in the register (sect. 32/1977)
PCNP Patent ceased through non-payment of renewal fee