GB1256404A - 0-oxa-3,8-diazaspiro(4,5)decan-2,4-diones - Google Patents
0-oxa-3,8-diazaspiro(4,5)decan-2,4-dionesInfo
- Publication number
- GB1256404A GB1256404A GB2836169A GB2836169A GB1256404A GB 1256404 A GB1256404 A GB 1256404A GB 2836169 A GB2836169 A GB 2836169A GB 2836169 A GB2836169 A GB 2836169A GB 1256404 A GB1256404 A GB 1256404A
- Authority
- GB
- United Kingdom
- Prior art keywords
- halogen
- benzyl
- june
- group iii
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229910052736 halogen Inorganic materials 0.000 abstract 5
- 150000002367 halogens Chemical class 0.000 abstract 4
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 abstract 3
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 3
- 125000003236 benzoyl group Chemical class [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 abstract 2
- 230000003993 interaction Effects 0.000 abstract 2
- XQRLXUYZKZXSBN-UHFFFAOYSA-N 1-benzyl-4-hydroxypiperidine-4-carbonitrile Chemical compound C1CC(O)(C#N)CCN1CC1=CC=CC=C1 XQRLXUYZKZXSBN-UHFFFAOYSA-N 0.000 abstract 1
- SJZKULRDWHPHGG-UHFFFAOYSA-N 1-benzylpiperidin-4-one Chemical compound C1CC(=O)CCN1CC1=CC=CC=C1 SJZKULRDWHPHGG-UHFFFAOYSA-N 0.000 abstract 1
- QTYNRNCLRXPYHQ-UHFFFAOYSA-N 1-oxa-3,8-diazaspiro[4.5]decane-2,4-dione Chemical class O1C(=O)NC(=O)C11CCNCC1 QTYNRNCLRXPYHQ-UHFFFAOYSA-N 0.000 abstract 1
- 238000006683 Mannich reaction Methods 0.000 abstract 1
- 229930040373 Paraformaldehyde Natural products 0.000 abstract 1
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 230000002152 alkylating effect Effects 0.000 abstract 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000911 decarboxylating effect Effects 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 230000007062 hydrolysis Effects 0.000 abstract 1
- 238000006460 hydrolysis reaction Methods 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
- YDNLNVZZTACNJX-UHFFFAOYSA-N isocyanatomethylbenzene Chemical compound O=C=NCC1=CC=CC=C1 YDNLNVZZTACNJX-UHFFFAOYSA-N 0.000 abstract 1
- 125000004674 methylcarbonyl group Chemical group CC(=O)* 0.000 abstract 1
- 229920002866 paraformaldehyde Polymers 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
- 239000004089 psychotropic agent Substances 0.000 abstract 1
- 239000000376 reactant Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP3902768 | 1968-06-07 | ||
| JP3985768 | 1968-06-10 | ||
| JP3985868 | 1968-06-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1256404A true GB1256404A (en) | 1971-12-08 |
Family
ID=27290018
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2836169A Expired GB1256404A (en) | 1968-06-07 | 1969-06-04 | 0-oxa-3,8-diazaspiro(4,5)decan-2,4-diones |
Country Status (6)
| Country | Link |
|---|---|
| BE (1) | BE734203A (enrdf_load_stackoverflow) |
| CH (1) | CH517111A (enrdf_load_stackoverflow) |
| DE (1) | DE1928704A1 (enrdf_load_stackoverflow) |
| FR (1) | FR2010411B1 (enrdf_load_stackoverflow) |
| GB (1) | GB1256404A (enrdf_load_stackoverflow) |
| SE (1) | SE350051B (enrdf_load_stackoverflow) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111574537A (zh) * | 2020-05-20 | 2020-08-25 | 成都药明康德新药开发有限公司 | 叔丁基-8-氧杂-3,11-二氮杂螺[5.6]十二烷-3-甲酸基酯的合成方法 |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE790675A (fr) * | 1971-10-29 | 1973-04-27 | Science Union & Cie | Nouveaux derives de l'oxa-1 diaza-3,8 spiro (4,5) decane |
| HU204529B (en) * | 1989-08-10 | 1992-01-28 | Richter Gedeon Vegyeszet | Process for producing new 1-oxa-2-oxo-8-aza-spiro(4,5)decane derivatives and pharmaceutical compositions containing them |
| FR2691459B1 (fr) * | 1992-05-25 | 1995-06-09 | Adir | Nouveaux derives de la phenothiazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
-
1969
- 1969-06-04 GB GB2836169A patent/GB1256404A/en not_active Expired
- 1969-06-05 SE SE797069A patent/SE350051B/xx unknown
- 1969-06-06 BE BE734203D patent/BE734203A/xx unknown
- 1969-06-06 DE DE19691928704 patent/DE1928704A1/de active Pending
- 1969-06-09 CH CH872969A patent/CH517111A/de not_active IP Right Cessation
- 1969-06-09 FR FR6918987A patent/FR2010411B1/fr not_active Expired
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111574537A (zh) * | 2020-05-20 | 2020-08-25 | 成都药明康德新药开发有限公司 | 叔丁基-8-氧杂-3,11-二氮杂螺[5.6]十二烷-3-甲酸基酯的合成方法 |
| CN111574537B (zh) * | 2020-05-20 | 2022-11-15 | 成都药明康德新药开发有限公司 | 叔丁基-8-氧杂-3,11-二氮杂螺[5.6]十二烷-3-甲酸基酯的合成方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| BE734203A (enrdf_load_stackoverflow) | 1969-11-17 |
| FR2010411B1 (enrdf_load_stackoverflow) | 1973-07-13 |
| DE1928704A1 (de) | 1969-12-11 |
| SE350051B (enrdf_load_stackoverflow) | 1972-10-16 |
| CH517111A (de) | 1971-12-31 |
| FR2010411A1 (enrdf_load_stackoverflow) | 1970-02-13 |
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