ES8300711A1 - Un procedimiento para la preparacion de un derivado cis-4,5-disustituidos de imidazolidin-2-ona opticamente activo. - Google Patents

Un procedimiento para la preparacion de un derivado cis-4,5-disustituidos de imidazolidin-2-ona opticamente activo.

Info

Publication number
ES8300711A1
ES8300711A1 ES503878A ES503878A ES8300711A1 ES 8300711 A1 ES8300711 A1 ES 8300711A1 ES 503878 A ES503878 A ES 503878A ES 503878 A ES503878 A ES 503878A ES 8300711 A1 ES8300711 A1 ES 8300711A1
Authority
ES
Spain
Prior art keywords
imidazolidin
optically active
cis
derivatives
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES503878A
Other languages
English (en)
Other versions
ES503878A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Chemical Co Ltd
Original Assignee
Sumitomo Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Chemical Co Ltd filed Critical Sumitomo Chemical Co Ltd
Publication of ES503878A0 publication Critical patent/ES503878A0/es
Publication of ES8300711A1 publication Critical patent/ES8300711A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/32—One oxygen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS CIS-4,5-DISUSTITUIDOS DE AMIDAZOILIDIN-2-ONA OPTICAMENTE ACTIVO, DE FORMULA (I), EN LA QUE R ES ALQUILO C <003> O BENCILO; Y R W ARALQUILO QUIRAL. CONSISTE EN LA REACCION DE 1,3-DIBENCIL-CIS-4,5-DICARBOXI-IMIDAZOLIDIN-2-ONA O SU ANHIDRIDO CON UNA AMINA SECUNDARIA DE FORMULA R R NH, EN LA QUE R Y R TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). LA REACCION SE LLEVA A CABO EN UN DISOLVENTE INERTE, EN PRESENCIA DE UNA BASE, A UNA TEMPERATURA ENTRE -20<025>C Y LA DE EBULLICION DEL DISOLVENTE. ESTOS COMPUESTOS TIENEN APLICACIONES COMO INTERMEDIOS PARA LA SINTESIS DE D-BIOTINA Y DE CANFORSULFONATO DE TRIMETAFANO.
ES503878A 1980-07-10 1981-07-10 Un procedimiento para la preparacion de un derivado cis-4,5-disustituidos de imidazolidin-2-ona opticamente activo. Expired ES8300711A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP55095818A JPS603387B2 (ja) 1980-07-10 1980-07-10 新規光学活性イミダゾリジン−２−オン誘導体およびその製法

Publications (2)

Publication Number Publication Date
ES503878A0 ES503878A0 (es) 1982-11-01
ES8300711A1 true ES8300711A1 (es) 1982-11-01

Family

ID=14147993

Family Applications (1)

Application Number Title Priority Date Filing Date
ES503878A Expired ES8300711A1 (es) 1980-07-10 1981-07-10 Un procedimiento para la preparacion de un derivado cis-4,5-disustituidos de imidazolidin-2-ona opticamente activo.

Country Status (6)

Country Link
US (1) US4403096A (es)
EP (1) EP0044158B1 (es)
JP (1) JPS603387B2 (es)
DE (1) DE3165558D1 (es)
ES (1) ES8300711A1 (es)
HU (1) HU186776B (es)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5852249A (ja) * 1981-09-24 1983-03-28 Sumitomo Chem Co Ltd 新規光学活性アミノアルコ−ルおよびその製法
US4496739A (en) * 1982-01-27 1985-01-29 Sumitomo Chemical Company, Limited Intermediates to optically active cis-1,3-dibenzyl-hexahydro-1H-furo[3,4-d]imidazole-2,4-dione
EP0092194B1 (en) * 1982-04-16 1987-07-08 Sumitomo Chemical Company, Limited Method of obtaining optically active half esters
DE3580390D1 (de) * 1984-05-18 1990-12-13 Hoffmann La Roche Verfahren zur herstellung eines lactons.
CH670644A5 (es) * 1986-12-18 1989-06-30 Lonza Ag
US6031003A (en) * 1991-08-23 2000-02-29 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
US6313146B1 (en) 1991-08-23 2001-11-06 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
US6011068A (en) * 1991-08-23 2000-01-04 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
US6001884A (en) * 1991-08-23 1999-12-14 Nps Pharmaceuticals, Inc. Calcium receptor-active molecules
WO1994024137A1 (en) * 1993-04-20 1994-10-27 Lonza Ltd. Asymmetric hydrogenation of furoimidazole derivatives
EP1553078A1 (en) 1994-10-21 2005-07-13 Nps Pharmaceuticals, Inc. Calcium receptor-active compounds
DE69739388D1 (de) * 1996-05-01 2009-06-10 Nps Pharma Inc Inorganische am Ionen-Rezeptor aktive Verbindungen
DE19947953A1 (de) * 1999-10-06 2001-04-12 Merck Patent Gmbh Verfahren zur selektiven Spaltung cyclischer Carbonsäureanhydride
CA2334746A1 (en) * 2000-02-09 2001-08-09 Sumitomo Chemical Co., Ltd. Process for producing optically active hemiesters
JPWO2021066043A1 (es) * 2019-10-01 2021-04-08

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3700659A (en) * 1970-11-17 1972-10-24 Hoffmann La Roche (+)-cis - 1,3-dibenzyl-hexahydro-1h-furo-(3,4-d)imidazole - 2,4 - dione,processes and intermediates
DE2229226C3 (de) * 1972-06-15 1980-11-06 Tanabe Seiyaku Co., Ltd., Osaka (Japan) Verfahren zur Herstellung von d-3,4-(l'3'-Dibenzyl-2'-oxoimidazolido)-2-oxo-5-hydroxytetra-hydrofuran
DD111577A5 (es) * 1972-06-22 1975-02-20
US4014895A (en) * 1972-06-22 1977-03-29 Sumitomo Chemical Company, Limited Method for synthesis of optically active thiolactones
FR2262662B1 (es) * 1974-03-01 1978-08-11 Anvar

Also Published As

Publication number Publication date
JPS603387B2 (ja) 1985-01-28
ES503878A0 (es) 1982-11-01
US4403096A (en) 1983-09-06
JPS5721374A (en) 1982-02-04
HU186776B (en) 1985-09-30
DE3165558D1 (en) 1984-09-20
EP0044158B1 (en) 1984-08-15
EP0044158A1 (en) 1982-01-20

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