JPS57139073A - Novel dibenzo(b, e)oxepin derivative - Google Patents
Novel dibenzo(b, e)oxepin derivativeInfo
- Publication number
- JPS57139073A JPS57139073A JP56023139A JP2313981A JPS57139073A JP S57139073 A JPS57139073 A JP S57139073A JP 56023139 A JP56023139 A JP 56023139A JP 2313981 A JP2313981 A JP 2313981A JP S57139073 A JPS57139073 A JP S57139073A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound shown
- compound
- formulai
- cyclohexyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
NEW MATERIAL:A compound shown by the formulaI[R1 is 1W5C alkyl; R2 is group shown by the formula II or III; or R1 is cyclohexyl; R2 is -NH-(CH2)n-Y (Y is 1W5C alkylamino or hetero ring; n is 0, 1, 2, or 3)]and its acid addition salt.
EXAMPLE: 2-Cyclohexyl-11-{2-( diethylamino )ethyl}aimo-6,11-dihydrodibenzo[b, e]oxepin.
USE: An anticonvulsant, an antihistamine, or an improver for cerebral circulation.
PROCESS: A compound shown by the formula IV is reduced into a compound shown by the formula V, which is reacted with a halogenating agent, to give a compound shown by the formula VI. This compound is reacted with an amine (H-formula II, H-formula III, Y-(CH2)n-NH2), to give a compound shown by the formulaI.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56023139A JPS57139073A (en) | 1981-02-20 | 1981-02-20 | Novel dibenzo(b, e)oxepin derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56023139A JPS57139073A (en) | 1981-02-20 | 1981-02-20 | Novel dibenzo(b, e)oxepin derivative |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS57139073A true JPS57139073A (en) | 1982-08-27 |
JPH0125749B2 JPH0125749B2 (en) | 1989-05-19 |
Family
ID=12102215
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP56023139A Granted JPS57139073A (en) | 1981-02-20 | 1981-02-20 | Novel dibenzo(b, e)oxepin derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57139073A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4999363A (en) * | 1988-06-09 | 1991-03-12 | Kyowa Hakko Kogyo Co., Ltd. | Tricyclic compounds |
US5010104A (en) * | 1987-10-14 | 1991-04-23 | Kyowa Hakko Kogyo Co., Ltd. | Tricyclic compounds |
-
1981
- 1981-02-20 JP JP56023139A patent/JPS57139073A/en active Granted
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5010104A (en) * | 1987-10-14 | 1991-04-23 | Kyowa Hakko Kogyo Co., Ltd. | Tricyclic compounds |
US5010087A (en) * | 1987-10-14 | 1991-04-23 | Kyowa Hakko Kogyo Co., Ltd. | Tricyclic compounds and TXA2 antagonistic compositions thereof |
US4999363A (en) * | 1988-06-09 | 1991-03-12 | Kyowa Hakko Kogyo Co., Ltd. | Tricyclic compounds |
US5302596A (en) * | 1988-06-09 | 1994-04-12 | Kyowa Hakko Kogyo Co., Ltd. | Tricyclic compounds as TXA2 antagonists |
Also Published As
Publication number | Publication date |
---|---|
JPH0125749B2 (en) | 1989-05-19 |
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