FR2218881A1 - Cis-3-(2,4-Dimethoxyphenyl)-crotonic acid - with choleretic and spasmolytic activity - Google Patents

Cis-3-(2,4-Dimethoxyphenyl)-crotonic acid - with choleretic and spasmolytic activity

Info

Publication number
FR2218881A1
FR2218881A1 FR7306273A FR7306273A FR2218881A1 FR 2218881 A1 FR2218881 A1 FR 2218881A1 FR 7306273 A FR7306273 A FR 7306273A FR 7306273 A FR7306273 A FR 7306273A FR 2218881 A1 FR2218881 A1 FR 2218881A1
Authority
FR
France
Prior art keywords
choleretic
dimethoxyphenyl
cis
crotonic acid
spasmolytic activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7306273A
Other languages
French (fr)
Other versions
FR2218881B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Unicler
Original Assignee
Unicler
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Unicler filed Critical Unicler
Priority to FR7306273A priority Critical patent/FR2218881A1/en
Priority to DE19742403752 priority patent/DE2403752A1/en
Publication of FR2218881A1 publication Critical patent/FR2218881A1/en
Application granted granted Critical
Publication of FR2218881B1 publication Critical patent/FR2218881B1/fr
Granted legal-status Critical Current

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Title acid of formula (I): and its alkali(ne earth) salts, its addn. salts with org. bases and its esters can be used in the treatment of disorders associated with hepatic insufficiency or deficient biliary function. (I) is prepd. by reacting 4-methyl-7-methoxycoumarin with excess methyl sulphate in a constantly strongly basic medium at is not >60 degrees C.
FR7306273A 1973-02-22 1973-02-22 Cis-3-(2,4-Dimethoxyphenyl)-crotonic acid - with choleretic and spasmolytic activity Granted FR2218881A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FR7306273A FR2218881A1 (en) 1973-02-22 1973-02-22 Cis-3-(2,4-Dimethoxyphenyl)-crotonic acid - with choleretic and spasmolytic activity
DE19742403752 DE2403752A1 (en) 1973-02-22 1974-01-26 CIS- (2,4-DIMETHOXYPHENYL) -3-CROTONIC ACID, SALT OF THIS ACID, AND PHARMACEUTICAL AGENTS CONTAINING THESE COMPOUNDS

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7306273A FR2218881A1 (en) 1973-02-22 1973-02-22 Cis-3-(2,4-Dimethoxyphenyl)-crotonic acid - with choleretic and spasmolytic activity

Publications (2)

Publication Number Publication Date
FR2218881A1 true FR2218881A1 (en) 1974-09-20
FR2218881B1 FR2218881B1 (en) 1976-03-05

Family

ID=9115247

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7306273A Granted FR2218881A1 (en) 1973-02-22 1973-02-22 Cis-3-(2,4-Dimethoxyphenyl)-crotonic acid - with choleretic and spasmolytic activity

Country Status (2)

Country Link
DE (1) DE2403752A1 (en)
FR (1) FR2218881A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3010474A1 (en) * 1980-03-19 1981-10-01 Basf Ag, 6700 Ludwigshafen 4- (DIHYDROXYPHEN-L-YL) -CROTONIC ACID AND ITS DERIVATIVES AND METHOD FOR PRODUCING THESE COMPOUNDS
KR100829894B1 (en) * 2007-04-09 2008-05-19 주식회사 코아팜 Preparing method of dimecrotic acid and magnesium salt thereof
KR100958678B1 (en) * 2008-10-21 2010-05-20 (주)파인켐 Method for preparing cis-dimecrotic acid and salt thereof

Also Published As

Publication number Publication date
DE2403752A1 (en) 1974-09-05
FR2218881B1 (en) 1976-03-05

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