FR2274283A1 - Vincamine 2-(para hydroxy benzoyl) benzoate - vasodilator and cerebral oxygenator-from salts of vincamine and the substd benzoic acid - Google Patents

Vincamine 2-(para hydroxy benzoyl) benzoate - vasodilator and cerebral oxygenator-from salts of vincamine and the substd benzoic acid

Info

Publication number
FR2274283A1
FR2274283A1 FR7420333A FR7420333A FR2274283A1 FR 2274283 A1 FR2274283 A1 FR 2274283A1 FR 7420333 A FR7420333 A FR 7420333A FR 7420333 A FR7420333 A FR 7420333A FR 2274283 A1 FR2274283 A1 FR 2274283A1
Authority
FR
France
Prior art keywords
vincamine
oxygenator
vasodilator
cerebral
benzoate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7420333A
Other languages
French (fr)
Other versions
FR2274283B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Castaigne SA
Original Assignee
Castaigne SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Castaigne SA filed Critical Castaigne SA
Priority to FR7420333A priority Critical patent/FR2274283A1/en
Publication of FR2274283A1 publication Critical patent/FR2274283A1/en
Application granted granted Critical
Publication of FR2274283B1 publication Critical patent/FR2274283B1/fr
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D461/00Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C65/00Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C65/32Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups
    • C07C65/40Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing keto groups containing singly bound oxygen-containing groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Vincamine 2-(p-hydroxybenzoyl)benzoate (I) is new. and is useful as a vasodilator and cerebral oxygenator with weak hypotensive and sedative properties. The salt (I) liberates vincamine slowly and so maintains a constant level of vincamine in the blood for prolonged periods. There is therefore no need to administer vincamine in frequent, small dosages to achieve the same effect.
FR7420333A 1974-06-12 1974-06-12 Vincamine 2-(para hydroxy benzoyl) benzoate - vasodilator and cerebral oxygenator-from salts of vincamine and the substd benzoic acid Granted FR2274283A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7420333A FR2274283A1 (en) 1974-06-12 1974-06-12 Vincamine 2-(para hydroxy benzoyl) benzoate - vasodilator and cerebral oxygenator-from salts of vincamine and the substd benzoic acid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7420333A FR2274283A1 (en) 1974-06-12 1974-06-12 Vincamine 2-(para hydroxy benzoyl) benzoate - vasodilator and cerebral oxygenator-from salts of vincamine and the substd benzoic acid

Publications (2)

Publication Number Publication Date
FR2274283A1 true FR2274283A1 (en) 1976-01-09
FR2274283B1 FR2274283B1 (en) 1978-06-30

Family

ID=9139947

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7420333A Granted FR2274283A1 (en) 1974-06-12 1974-06-12 Vincamine 2-(para hydroxy benzoyl) benzoate - vasodilator and cerebral oxygenator-from salts of vincamine and the substd benzoic acid

Country Status (1)

Country Link
FR (1) FR2274283A1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2714486A1 (en) * 1976-03-31 1977-10-06 Ferrer Int VINCAMINE DERIVATIVE, METHOD OF MANUFACTURING AND MEDICINAL PRODUCTS MANUFACTURED FROM THEM
DE2725246A1 (en) * 1976-06-03 1977-12-22 Corvi Mora E DERIVATIVES OF VINCAMIN AND APOVINCAMIN AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2714486A1 (en) * 1976-03-31 1977-10-06 Ferrer Int VINCAMINE DERIVATIVE, METHOD OF MANUFACTURING AND MEDICINAL PRODUCTS MANUFACTURED FROM THEM
DE2725246A1 (en) * 1976-06-03 1977-12-22 Corvi Mora E DERIVATIVES OF VINCAMIN AND APOVINCAMIN AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM

Also Published As

Publication number Publication date
FR2274283B1 (en) 1978-06-30

Similar Documents

Publication Publication Date Title
AT347604B (en) PROCESS FOR THE PREPARATION OF NEW DOUBLE SALTS OF S-ADENOSIL-L-METHIONINE WITH SULFURIC ACID AND P-TOLUENE SULPHONIC ACID
BE861167A (en) STABLE MIXTURE FOR CONSERVATION GIVING BY DISSOLUTION IN WATER A SOLUTION WITH HIGH ANTIMICROBIAL ACTIVITY
ES458710A1 (en) Long acting preparation of cefalexin
FR2274283A1 (en) Vincamine 2-(para hydroxy benzoyl) benzoate - vasodilator and cerebral oxygenator-from salts of vincamine and the substd benzoic acid
BE816855A (en) NEW ESTER ISOMER AND ACID ADDITIONAL SALTS
AT280301B (en) Process for the preparation of new racemic or optically active piperazine derivatives and of their acid addition salts
MY100483A (en) Niflumic acid morpholinoethyl ester diniflumate, preparation, use in therapeutics as analgesic and anti- inflammatory
IE35118B1 (en) Amino derivatives of pyrazolo-pyridine carboxylic acids and esters and salts thereof
AT303703B (en) Process for the preparation of new α-aminoxycarbonyl-hydroxamic acid derivatives, their optically active isomers and pharmaceutically acceptable acid addition salts
BE790343A (en) METHOD OF IMPROVING THE STABILITY OF STORAGE OF ENZYMES
ES376688A1 (en) Benzdiazepine derivatives
FR2218881A1 (en) Cis-3-(2,4-Dimethoxyphenyl)-crotonic acid - with choleretic and spasmolytic activity
ES416304A1 (en) 2-Alkyl-4(3H)-pteridinone compounds and therapeutic compositions
CA1028329A (en) Amine and sodium salts of mono and diesters of 2,5-dihydroxybenzene sulfonic acid
IE36393L (en) Salts of chlorhexidine
FR2365569A1 (en) Heterocyclic-(1,2-a)-pyrimidine carboxylic acids - with antiinflammatory, analgesic, antithrombotic, antiarteriosclerotic and tranquillising activity
BE753153A (en) Antimicrobial n-subst 6,7-methylenedioxy-4- - quinolone derivs prepn
ES404928A1 (en) 2-(3{40 -trifluoromethylthio-anilino)-benzoic acid and salts thereof with pharmaceutically acceptable bases
FR2100729A1 (en) Ampicillin-guaiacolsulfonic acid prodn - by reacting guaiacolsulphonic acid with ampicillin trihydrate
NL7703682A (en) Antiinflammatory, analgesic alclofenac lysine salt - with improved bio-availability and suitable for admin. by injection
FR2456098A2 (en) Antiinflammatory and antipyretic thiazolo-(3,4-b)-isoquinoline derivs. - prepd. e.g. by cyclisation of 3-hydroxymethyl-N-iso-quinolyl-tetra-hydro-isoquinoline-2-thio:ca- rboxamide cpds.
JPS52100441A (en) Separation of racemic and optically active salts of p-hydroxyphenyl gl ycine with sulfonic acid derivatives
FR2298321A1 (en) Synergistic cinnarizine compsn - with clofibrate or clofibrinic acid and analogues with hypolipaemic activity
FR2375217A1 (en) 2-Bromo-3-chloro(N)-2-imidazolidinylidene-benz:amine - for use as antihypertensive with prolonged duration of activity
ES8504132A1 (en) Novel 2-hydroxybenzoic acid imidazoles and manufacture

Legal Events

Date Code Title Description
ST Notification of lapse