GB1153578A - Phenyl-Isopropylamine Derivatives - Google Patents

Phenyl-Isopropylamine Derivatives

Info

Publication number
GB1153578A
GB1153578A GB1952666A GB1952666A GB1153578A GB 1153578 A GB1153578 A GB 1153578A GB 1952666 A GB1952666 A GB 1952666A GB 1952666 A GB1952666 A GB 1952666A GB 1153578 A GB1153578 A GB 1153578A
Authority
GB
United Kingdom
Prior art keywords
hydrogen
group
compositions
agents
antidepressive
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1952666A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chinoin Private Co Ltd
Original Assignee
Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt filed Critical Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Publication of GB1153578A publication Critical patent/GB1153578A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1,153,578. Antidepressive &c. compositions. CHINOIN GYOGYSZER-ES VEGYESZETI TERMEKEK GYARA RT. 3 May, 1966 [3 May, 1965], No. 19526/66. Addition to 1,142,981. Heading A5B. [Also in Division C2] Pharmaceutical compositions having antidepressive, metabolism-increasing and MAO- inhibiting activity comprise an optically active compound of formula I: wherein R<SP>1</SP> is a C 1-5 alkyl group, R<SP>2</SP> is a propyl, propenyl or proynyl group which may be substituted by a hydroxy group or halogen atom or, if R<SP>3</SP> and/or R<SP>4</SP> is not hydrogen, R<SP>2</SP> may also be hydrogen, and R<SP>3</SP> and R<SP>4</SP> are each hydrogen, halogen or a nitro, amino or diazonium group, or an acid addition salt thereof, together with a carrier. The compositions may be administered orally, rectally or parenterally and may contain other pharmaceutically active components, e.g. analgesics, blood-pressure decreasing agents, sedatives, anti-inflammatory agents, diuretics, coronary-flow increasing agents or spasmolytics.
GB1952666A 1962-03-30 1966-05-03 Phenyl-Isopropylamine Derivatives Expired GB1153578A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HUCI000941 1962-03-30
HUCI000542 1965-05-03

Publications (1)

Publication Number Publication Date
GB1153578A true GB1153578A (en) 1969-05-29

Family

ID=26318374

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1952666A Expired GB1153578A (en) 1962-03-30 1966-05-03 Phenyl-Isopropylamine Derivatives

Country Status (2)

Country Link
DE (2) DE1227447B (en)
GB (1) GB1153578A (en)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0011608A1 (en) * 1978-08-30 1980-05-28 Astra Läkemedel Aktiebolag Novel allenic amine and acid addition salts thereof, a process for their preparation, pharmaceutical preparations comprising them and the use of these compounds in the preparation of pharmaceutical compositions
WO1988004552A1 (en) * 1986-12-19 1988-06-30 Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. Composition to prevent seasickness
WO1990001928A1 (en) * 1988-08-17 1990-03-08 Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. Composition for the treatment of schizophrenia
EP0407032A2 (en) * 1989-06-02 1991-01-09 JOHN WYETH &amp; BROTHER LIMITED Aromatic and heteroaromatic amines for treating depressions, cerebral insufficiency disorders or dementia
WO1993012775A1 (en) * 1991-12-20 1993-07-08 Chinoin Gyógyszer- És Vegyészeti Termékek Gyára Rt. Pharmaceutical composition and process for the preparation thereof
WO1997011927A1 (en) * 1995-09-26 1997-04-03 Basf Aktiengesellschaft Method of resolving racemic mixtures
US5817336A (en) * 1993-04-02 1998-10-06 Orion-Yhtyma Oy Composition containing selegiline
CZ297382B6 (en) * 1995-03-02 2006-11-15 R.P. Scherer Limited Rapidly dispersing oral solid dosage form of pharmaceutical for the treatment of Parkinson's disease

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU207282B (en) * 1984-05-31 1993-03-29 Chinoin Gyogyszer Es Vegyeszet Process for producing phenyl-alkyl-amine derivatives and pharmaceutical compositions containing them
US5220068A (en) * 1986-09-25 1993-06-15 Chinoin Gyogyszer - Es Vegyeszeti Termekek Gyara Rt. Psychostimulant agent
HU207280B (en) * 1986-09-25 1993-03-29 Chinoin Gyogyszer Es Vegyeszet Process for producing new phenyl-alkyl-amines and pharmaceutical compositions containing them
CS269271B1 (en) * 1988-05-30 1990-04-11 Hajicek Josef Method of selegiline's hydrochloride production
CN110105579B (en) * 2019-05-06 2020-06-30 四川大学 Intracellular tracing carrier with main chain containing spiropyran as well as preparation and application thereof

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0011608A1 (en) * 1978-08-30 1980-05-28 Astra Läkemedel Aktiebolag Novel allenic amine and acid addition salts thereof, a process for their preparation, pharmaceutical preparations comprising them and the use of these compounds in the preparation of pharmaceutical compositions
WO1988004552A1 (en) * 1986-12-19 1988-06-30 Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. Composition to prevent seasickness
US4925878A (en) * 1986-12-19 1990-05-15 Chinoin Gyogyszer- Es Vegyeszeti Termekek Gyara Rt. Method to prevent seasickness
WO1990001928A1 (en) * 1988-08-17 1990-03-08 Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. Composition for the treatment of schizophrenia
EP0407032A2 (en) * 1989-06-02 1991-01-09 JOHN WYETH &amp; BROTHER LIMITED Aromatic and heteroaromatic amines for treating depressions, cerebral insufficiency disorders or dementia
EP0407032A3 (en) * 1989-06-02 1992-01-02 John Wyeth & Brother Limited Aromatic and heteroaromatic amines for treating depressions, cerebral insufficiency disorders or dementia
GB2233558B (en) * 1989-06-02 1993-12-15 Wyeth John & Brother Ltd Psychotropic use of aromatic amines
WO1993012775A1 (en) * 1991-12-20 1993-07-08 Chinoin Gyógyszer- És Vegyészeti Termékek Gyára Rt. Pharmaceutical composition and process for the preparation thereof
US5817336A (en) * 1993-04-02 1998-10-06 Orion-Yhtyma Oy Composition containing selegiline
CZ297382B6 (en) * 1995-03-02 2006-11-15 R.P. Scherer Limited Rapidly dispersing oral solid dosage form of pharmaceutical for the treatment of Parkinson's disease
WO1997011927A1 (en) * 1995-09-26 1997-04-03 Basf Aktiengesellschaft Method of resolving racemic mixtures
US6015903A (en) * 1995-09-26 2000-01-18 Basf Aktiengesellschaft Method of resolving racemic mixtures

Also Published As

Publication number Publication date
DE1568277A1 (en) 1970-04-30
DE1227447B (en) 1966-10-27
DE1568277B2 (en) 1976-12-23

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