GB1250792A - - Google Patents
Info
- Publication number
- GB1250792A GB1250792A GB4728568A GB4728568A GB1250792A GB 1250792 A GB1250792 A GB 1250792A GB 4728568 A GB4728568 A GB 4728568A GB 4728568 A GB4728568 A GB 4728568A GB 1250792 A GB1250792 A GB 1250792A
- Authority
- GB
- United Kingdom
- Prior art keywords
- alkyl
- pharmaceutical
- march
- oct
- compositions
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- -1 analgesic Substances 0.000 abstract 2
- 229910052799 carbon Inorganic materials 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 125000006700 (C1-C6) alkylthio group Chemical group 0.000 abstract 1
- 101100188555 Arabidopsis thaliana OCT6 gene Proteins 0.000 abstract 1
- 125000005236 alkanoylamino group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000005277 alkyl imino group Chemical group 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 230000000202 analgesic effect Effects 0.000 abstract 1
- 230000003474 anti-emetic effect Effects 0.000 abstract 1
- 230000001387 anti-histamine Effects 0.000 abstract 1
- 239000002111 antiemetic agent Substances 0.000 abstract 1
- 239000000739 antihistaminic agent Substances 0.000 abstract 1
- 239000003874 central nervous system depressant Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 125000000219 ethylidene group Chemical group [H]C(=[*])C([H])([H])[H] 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000002048 spasmolytic effect Effects 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/30—Oxygen or sulfur atoms
- C07D233/32—One oxygen atom
- C07D233/36—One oxygen atom with hydrocarbon radicals, substituted by nitrogen atoms, attached to ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
- C07D313/02—Seven-membered rings
- C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D313/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D313/14—[b,f]-condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
- C07D337/02—Seven-membered rings
- C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D337/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D337/14—[b,f]-condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP6454067 | 1967-10-06 | ||
| CH1410867 | 1967-10-09 | ||
| JP8173167 | 1967-12-20 | ||
| JP528068 | 1968-01-29 | ||
| JP1277368 | 1968-02-28 | ||
| JP1396668 | 1968-03-04 | ||
| JP1812268 | 1968-03-19 | ||
| JP2391768 | 1968-04-10 | ||
| JP4403368 | 1968-06-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1250792A true GB1250792A (enrdf_load_stackoverflow) | 1971-10-20 |
Family
ID=27575807
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4728568A Expired GB1250792A (enrdf_load_stackoverflow) | 1967-10-06 | 1968-10-04 |
Country Status (9)
| Country | Link |
|---|---|
| AT (1) | AT306721B (enrdf_load_stackoverflow) |
| BE (1) | BE721822A (enrdf_load_stackoverflow) |
| CA (1) | CA1017331A (enrdf_load_stackoverflow) |
| CH (5) | CH539044A (enrdf_load_stackoverflow) |
| DE (1) | DE1801523A1 (enrdf_load_stackoverflow) |
| FR (1) | FR8456M (enrdf_load_stackoverflow) |
| GB (1) | GB1250792A (enrdf_load_stackoverflow) |
| NL (1) | NL6814346A (enrdf_load_stackoverflow) |
| SE (1) | SE361665B (enrdf_load_stackoverflow) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE757868A (fr) * | 1969-10-25 | 1971-04-01 | Spofa Usines Pharma Reunies | Procede de preparation de nouvelles 10-piperazino-10,11-dihydrodibenzo/b,f,/thiepines et de leurs sels, ainsi que les produits obtenus |
| BE791348A (fr) * | 1971-11-16 | 1973-05-14 | Hoffmann La Roche | Composes tricycliques |
| JPS4891213A (enrdf_load_stackoverflow) * | 1972-03-06 | 1973-11-28 | ||
| US3996229A (en) * | 1974-01-14 | 1976-12-07 | Hoffmann-La Roche Inc. | 1-[10,11-Dihydro-dibenzo[b,f]-thiepin-10-yl]-4-(alkynylalkyl)-piperazines |
| US4198418A (en) * | 1979-01-10 | 1980-04-15 | American Hoechst Corporation | Spiro[dibenz(b,f)oxepin-piperidine]s |
| CA1172565A (en) * | 1980-04-25 | 1984-08-14 | Alfred Boris | Anti-inflammatory methods and compositions |
| GB8607684D0 (en) * | 1986-03-27 | 1986-04-30 | Ici America Inc | Thiazepine compounds |
| JPH04211071A (ja) * | 1990-03-05 | 1992-08-03 | Hokuriku Seiyaku Co Ltd | 多環式化合物 |
| US5602124A (en) * | 1994-12-12 | 1997-02-11 | Allelix Biopharmaceuticals, Inc. | 5-HT2 receptor ligands |
| US7355042B2 (en) | 2001-10-16 | 2008-04-08 | Hypnion, Inc. | Treatment of CNS disorders using CNS target modulators |
-
1967
- 1967-10-09 CH CH539044D patent/CH539044A/de not_active IP Right Cessation
-
1968
- 1968-10-02 CA CA031,475A patent/CA1017331A/en not_active Expired
- 1968-10-04 CH CH353971A patent/CH537395A/de not_active IP Right Cessation
- 1968-10-04 FR FR168864A patent/FR8456M/fr not_active Expired
- 1968-10-04 SE SE13428/68A patent/SE361665B/xx unknown
- 1968-10-04 GB GB4728568A patent/GB1250792A/en not_active Expired
- 1968-10-04 AT AT973568A patent/AT306721B/de not_active IP Right Cessation
- 1968-10-04 BE BE721822A patent/BE721822A/xx unknown
- 1968-10-04 CH CH1481768A patent/CH539056A/de not_active IP Right Cessation
- 1968-10-04 CH CH1523271A patent/CH553212A/xx not_active IP Right Cessation
- 1968-10-04 CH CH1262573A patent/CH554347A/xx not_active IP Right Cessation
- 1968-10-05 DE DE19681801523 patent/DE1801523A1/de not_active Withdrawn
- 1968-10-07 NL NL6814346A patent/NL6814346A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AT306721B (de) | 1973-04-25 |
| CH539044A (de) | 1973-08-31 |
| CH539056A (de) | 1973-08-31 |
| CA1017331A (en) | 1977-09-13 |
| FR8456M (enrdf_load_stackoverflow) | 1971-09-10 |
| CH537395A (de) | 1973-07-13 |
| BE721822A (enrdf_load_stackoverflow) | 1969-04-04 |
| SE361665B (enrdf_load_stackoverflow) | 1973-11-12 |
| DE1801523A1 (de) | 1969-06-19 |
| CH554347A (de) | 1974-09-30 |
| NL6814346A (enrdf_load_stackoverflow) | 1969-04-09 |
| CH553212A (de) | 1974-08-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |