AT306721B - Verfahren zur Herstellung von neuen tricyclischen Enaminen sowie von deren Säure-Additionssalzen und quarternären Ammoniumsalzen - Google Patents

Verfahren zur Herstellung von neuen tricyclischen Enaminen sowie von deren Säure-Additionssalzen und quarternären Ammoniumsalzen

Info

Publication number
AT306721B
AT306721B AT973568A AT973568A AT306721B AT 306721 B AT306721 B AT 306721B AT 973568 A AT973568 A AT 973568A AT 973568 A AT973568 A AT 973568A AT 306721 B AT306721 B AT 306721B
Authority
AT
Austria
Prior art keywords
enamines
preparation
quaternary ammonium
acid addition
salts
Prior art date
Application number
AT973568A
Other languages
English (en)
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Application granted granted Critical
Publication of AT306721B publication Critical patent/AT306721B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/15—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30—Oxygen or sulfur atoms
    • C07D233/32—One oxygen atom
    • C07D233/36—One oxygen atom with hydrocarbon radicals, substituted by nitrogen atoms, attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02—Seven-membered rings
    • C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D313/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D313/14—[b,f]-condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
    • C07D337/02—Seven-membered rings
    • C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D337/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D337/14—[b,f]-condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT973568A 1967-10-06 1968-10-04 Verfahren zur Herstellung von neuen tricyclischen Enaminen sowie von deren Säure-Additionssalzen und quarternären Ammoniumsalzen AT306721B (de)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
JP6454067 1967-10-06
CH1410867 1967-10-09
JP8173167 1967-12-20
JP528068 1968-01-29
JP1277368 1968-02-28
JP1396668 1968-03-04
JP1812268 1968-03-19
JP2391768 1968-04-10
JP4403368 1968-06-24

Publications (1)

Publication Number Publication Date
AT306721B true AT306721B (de) 1973-04-25

Family

ID=27575807

Family Applications (1)

Application Number Title Priority Date Filing Date
AT973568A AT306721B (de) 1967-10-06 1968-10-04 Verfahren zur Herstellung von neuen tricyclischen Enaminen sowie von deren Säure-Additionssalzen und quarternären Ammoniumsalzen

Country Status (9)

Country Link
AT (1) AT306721B (de)
BE (1) BE721822A (de)
CA (1) CA1017331A (de)
CH (5) CH539044A (de)
DE (1) DE1801523A1 (de)
FR (1) FR8456M (de)
GB (1) GB1250792A (de)
NL (1) NL6814346A (de)
SE (1) SE361665B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE757868A (fr) * 1969-10-25 1971-04-01 Spofa Usines Pharma Reunies Procede de preparation de nouvelles 10-piperazino-10,11-dihydrodibenzo/b,f,/thiepines et de leurs sels, ainsi que les produits obtenus
BE791348A (fr) * 1971-11-16 1973-05-14 Hoffmann La Roche Composes tricycliques
JPS4891213A (de) * 1972-03-06 1973-11-28
US3996229A (en) * 1974-01-14 1976-12-07 Hoffmann-La Roche Inc. 1-[10,11-Dihydro-dibenzo[b,f]-thiepin-10-yl]-4-(alkynylalkyl)-piperazines
US4198418A (en) * 1979-01-10 1980-04-15 American Hoechst Corporation Spiro[dibenz(b,f)oxepin-piperidine]s
IL62705A (en) * 1980-04-25 1986-04-29 Sparamedica Ag Topical anti-inflammatory pharmaceutical compositions containing piperazine derivatives
GB8607684D0 (en) * 1986-03-27 1986-04-30 Ici America Inc Thiazepine compounds
JPH04211071A (ja) * 1990-03-05 1992-08-03 Hokuriku Seiyaku Co Ltd 多環式化合物
US5602124A (en) * 1994-12-12 1997-02-11 Allelix Biopharmaceuticals, Inc. 5-HT2 receptor ligands
US7355042B2 (en) 2001-10-16 2008-04-08 Hypnion, Inc. Treatment of CNS disorders using CNS target modulators

Also Published As

Publication number Publication date
CH554347A (de) 1974-09-30
CA1017331A (en) 1977-09-13
GB1250792A (de) 1971-10-20
NL6814346A (de) 1969-04-09
CH539044A (de) 1973-08-31
CH537395A (de) 1973-07-13
SE361665B (de) 1973-11-12
FR8456M (de) 1971-09-10
DE1801523A1 (de) 1969-06-19
BE721822A (de) 1969-04-04
CH539056A (de) 1973-08-31
CH553212A (de) 1974-08-30

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Legal Events

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ELJ Ceased due to non-payment of the annual fee