GB1226350A - - Google Patents
Info
- Publication number
- GB1226350A GB1226350A GB1226350DA GB1226350A GB 1226350 A GB1226350 A GB 1226350A GB 1226350D A GB1226350D A GB 1226350DA GB 1226350 A GB1226350 A GB 1226350A
- Authority
- GB
- United Kingdom
- Prior art keywords
- anhydrous
- methylene
- introduce
- acid
- strong
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000002253 acid Substances 0.000 abstract 6
- 229910052794 bromium Inorganic materials 0.000 abstract 5
- 229910052801 chlorine Inorganic materials 0.000 abstract 5
- 239000000460 chlorine Substances 0.000 abstract 5
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 abstract 3
- 150000001732 carboxylic acid derivatives Chemical class 0.000 abstract 3
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical compound [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 abstract 2
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 2
- 101100241859 Mus musculus Oacyl gene Proteins 0.000 abstract 2
- GDTBXPJZTBHREO-UHFFFAOYSA-N bromine Substances BrBr GDTBXPJZTBHREO-UHFFFAOYSA-N 0.000 abstract 2
- 239000002904 solvent Substances 0.000 abstract 2
- CPELXLSAUQHCOX-UHFFFAOYSA-M Bromide Chemical compound [Br-] CPELXLSAUQHCOX-UHFFFAOYSA-M 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- KRHYYFGTRYWZRS-UHFFFAOYSA-M Fluoride anion Chemical compound [F-] KRHYYFGTRYWZRS-UHFFFAOYSA-M 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 1
- CPELXLSAUQHCOX-UHFFFAOYSA-N Hydrogen bromide Chemical compound Br CPELXLSAUQHCOX-UHFFFAOYSA-N 0.000 abstract 1
- 230000002280 anti-androgenic effect Effects 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 125000001475 halogen functional group Chemical group 0.000 abstract 1
- 239000012442 inert solvent Substances 0.000 abstract 1
- 239000012434 nucleophilic reagent Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
- 239000000583 progesterone congener Substances 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- 150000003431 steroids Chemical class 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DESC040435 | 1967-03-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1226350A true GB1226350A (enExample) | 1971-03-24 |
Family
ID=7435673
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1226350D Expired GB1226350A (enExample) | 1967-03-23 | 1968-03-25 |
Country Status (10)
| Country | Link |
|---|---|
| AT (1) | AT280495B (enExample) |
| BE (1) | BE712647A (enExample) |
| BR (1) | BR6897852D0 (enExample) |
| CH (3) | CH568334A5 (enExample) |
| DE (1) | DE1643016C3 (enExample) |
| DK (1) | DK122763B (enExample) |
| FR (1) | FR1578823A (enExample) |
| GB (1) | GB1226350A (enExample) |
| NL (1) | NL6804157A (enExample) |
| SE (1) | SE338313B (enExample) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102011108919B4 (de) | 2011-07-29 | 2019-06-13 | Multivac Sepp Haggenmüller Se & Co. Kg | Mehrspurige Schalenverschließmaschine |
-
1967
- 1967-03-23 DE DE1643016A patent/DE1643016C3/de not_active Expired
-
1968
- 1968-02-28 AT AT191868A patent/AT280495B/de not_active IP Right Cessation
- 1968-03-06 CH CH329068A patent/CH568334A5/xx not_active IP Right Cessation
- 1968-03-06 CH CH564272A patent/CH569037A5/xx not_active IP Right Cessation
- 1968-03-06 CH CH564372A patent/CH592689A5/xx not_active IP Right Cessation
- 1968-03-08 DK DK98968AA patent/DK122763B/da unknown
- 1968-03-21 SE SE03771/68A patent/SE338313B/xx unknown
- 1968-03-22 BE BE712647D patent/BE712647A/xx unknown
- 1968-03-22 NL NL6804157A patent/NL6804157A/xx unknown
- 1968-03-22 FR FR1578823D patent/FR1578823A/fr not_active Expired
- 1968-03-22 BR BR197852/68A patent/BR6897852D0/pt unknown
- 1968-03-25 GB GB1226350D patent/GB1226350A/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| NL6804157A (enExample) | 1968-09-24 |
| BR6897852D0 (pt) | 1973-02-08 |
| CH569037A5 (enExample) | 1975-11-14 |
| SE338313B (enExample) | 1971-09-06 |
| CH568334A5 (enExample) | 1975-10-31 |
| FR1578823A (enExample) | 1969-08-22 |
| AT280495B (de) | 1970-04-10 |
| DK122763B (da) | 1972-04-10 |
| DE1643016C3 (de) | 1975-06-12 |
| DE1643016B2 (de) | 1974-09-26 |
| BE712647A (enExample) | 1968-09-23 |
| CH592689A5 (enExample) | 1977-11-15 |
| DE1643016A1 (de) | 1971-04-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed | ||
| PCNP | Patent ceased through non-payment of renewal fee |