GB1179261A - Amides of Aliphatic Carboxylic Acids their Production and Use - Google Patents

Amides of Aliphatic Carboxylic Acids their Production and Use

Info

Publication number
GB1179261A
GB1179261A GB411567A GB411567A GB1179261A GB 1179261 A GB1179261 A GB 1179261A GB 411567 A GB411567 A GB 411567A GB 411567 A GB411567 A GB 411567A GB 1179261 A GB1179261 A GB 1179261A
Authority
GB
United Kingdom
Prior art keywords
reacting
acid
formula
amides
alkanol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB411567A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
JR Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by JR Geigy AG filed Critical JR Geigy AG
Publication of GB1179261A publication Critical patent/GB1179261A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Corsets Or Brassieres (AREA)

Abstract

1,179,261. N-Pyridyl-amides. J. R. GEIGY A.G. 27 Jan., 1967 [28 Jan., 1966], No. 4115/67. Heading C2C. N-Pyridyl-amides of Formula I wherein R 1 -CO- represents the acyl radical of an alkanoic acid, alkenoic acid or alkapolyene acid having 6 to 22 carbon atoms, R 2 represents hydrogen or C 1-4 alkyl and R 3 represents C 1-4 alkyl, and their acid addition salts, are prepared by esterifying a compound of Formula II The esterification may be performed by reacting a compound II with a diazo-alkane, or with a C 1-4 alkanol in the presence of a carbodiimide, or with carbonyl-1,1<SP>1</SP>-diimidazole followed by reacting the product with a C 1-4 alkanol, or with oxalyl chloride followed by reacting the resulting N-(chlorocarbonyl-pyridyl)-amide with a C 1-4 alkanol. Starting materials of Formula II are prepared by reacting a trihaloethyl ester of Formula III with zinc in a liquid organic acid. Trihaloethyl esters of Formula III are prepared by reacting an amino- or C 1-4 -alkylaminopyridine carboxylic acid with a 2,2,2-trihaloethanol, and acylating the resulting amino- or C 1-4 -alkylamino-pyridine carboxylic acid trihaloethyl ester.
GB411567A 1966-01-28 1967-01-27 Amides of Aliphatic Carboxylic Acids their Production and Use Expired GB1179261A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH123866A CH495986A (en) 1966-01-28 1966-01-28 Aliphatic carboxylic acid amides having antiviral and

Publications (1)

Publication Number Publication Date
GB1179261A true GB1179261A (en) 1970-01-28

Family

ID=4205698

Family Applications (1)

Application Number Title Priority Date Filing Date
GB411567A Expired GB1179261A (en) 1966-01-28 1967-01-27 Amides of Aliphatic Carboxylic Acids their Production and Use

Country Status (15)

Country Link
AT (1) AT265262B (en)
BE (1) BE693265A (en)
CH (1) CH495986A (en)
DE (1) DE1695008A1 (en)
DK (1) DK115261B (en)
ES (1) ES336150A1 (en)
FI (1) FI48078C (en)
FR (1) FR1510321A (en)
GB (1) GB1179261A (en)
GR (1) GR35674B (en)
IL (1) IL27339A (en)
NL (1) NL6701361A (en)
NO (1) NO122422B (en)
SE (1) SE325571B (en)
YU (1) YU32360B (en)

Also Published As

Publication number Publication date
YU32360B (en) 1974-10-31
NO122422B (en) 1971-06-28
DE1695008A1 (en) 1971-02-25
AT265262B (en) 1968-10-10
SE325571B (en) 1970-07-06
NL6701361A (en) 1967-07-31
GR35674B (en) 1968-10-17
YU14967A (en) 1974-04-30
FR1510321A (en) 1968-01-19
ES336150A1 (en) 1968-04-01
FI48078B (en) 1974-02-28
DK115261B (en) 1969-09-22
FI48078C (en) 1974-06-10
IL27339A (en) 1971-04-28
BE693265A (en) 1967-07-27
CH495986A (en) 1970-09-15

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