FR2081430A1 - Oxadiazoles, hypocholesterolaemics - Google Patents

Oxadiazoles, hypocholesterolaemics

Info

Publication number
FR2081430A1
FR2081430A1 FR7100995A FR7100995A FR2081430A1 FR 2081430 A1 FR2081430 A1 FR 2081430A1 FR 7100995 A FR7100995 A FR 7100995A FR 7100995 A FR7100995 A FR 7100995A FR 2081430 A1 FR2081430 A1 FR 2081430A1
Authority
FR
France
Prior art keywords
oxadiazoles
substd
opt
hypocholesterolaemics
hypochloesterolaemics
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7100995A
Other languages
French (fr)
Other versions
FR2081430B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of FR2081430A1 publication Critical patent/FR2081430A1/en
Application granted granted Critical
Publication of FR2081430B1 publication Critical patent/FR2081430B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/12—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines
    • C07C259/18—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups with replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines having carbon atoms of hydroxamidine groups bound to carbon atoms of six-membered aromatic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Oxadiazoles, hypochloesterolaemics. Cpds. of formula:- (where X is opt. esterified COOH or carboxamido; R1 and R2 are H, aryl or alkyl; R3 is opt. substd. hydrocarbyl or heterocyclyl), are useful for treating arterioscelrosis, and may be prepd. by reacting the corresp. X-CR1R2O-substd. benzamidoxime with an acid R3COOH or its anhydride, halide or ester.
FR7100995A 1970-01-14 1971-01-13 Oxadiazoles, hypocholesterolaemics Granted FR2081430A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP405770 1970-01-14
JP3334070 1970-04-17

Publications (2)

Publication Number Publication Date
FR2081430A1 true FR2081430A1 (en) 1971-12-03
FR2081430B1 FR2081430B1 (en) 1975-10-31

Family

ID=26337763

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7100995A Granted FR2081430A1 (en) 1970-01-14 1971-01-13 Oxadiazoles, hypocholesterolaemics

Country Status (10)

Country Link
BE (1) BE761586A (en)
CA (1) CA962684A (en)
CH (1) CH546782A (en)
DE (1) DE2101182A1 (en)
DK (1) DK139265B (en)
ES (1) ES387134A1 (en)
FR (1) FR2081430A1 (en)
NL (1) NL150789B (en)
NO (1) NO130478C (en)
SE (1) SE362881B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL159086A0 (en) * 2001-06-08 2004-05-12 Cytovia Inc 3-aryl-5-aryl- [1, 2, 4] -oxadiazole derivatives and pharmaceutical compositions containing the same
BRPI0720043A2 (en) 2006-12-15 2014-01-07 Abbott Lab OXADIAZOL COMPOUND
EP3642187A1 (en) * 2017-06-19 2020-04-29 Basf Se 2-[[5-(trifluoromethyl)-1,2,4-oxadiazol-3-yl]aryloxy](thio)acetamides for combating phytopathogenic fungi

Also Published As

Publication number Publication date
ES387134A1 (en) 1973-05-01
DK139265C (en) 1979-06-25
NO130478B (en) 1974-09-09
CH546782A (en) 1974-03-15
CA962684A (en) 1975-02-11
BE761586A (en) 1971-06-16
NO130478C (en) 1974-12-18
NL150789B (en) 1976-09-15
FR2081430B1 (en) 1975-10-31
NL7100482A (en) 1971-07-16
DE2101182A1 (en) 1971-07-22
SE362881B (en) 1973-12-27
DK139265B (en) 1979-01-22

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Legal Events

Date Code Title Description
ST Notification of lapse