GB1114150A - Method of producing ª‡-tocopheryl acid succinate - Google Patents

Method of producing ª‡-tocopheryl acid succinate

Info

Publication number
GB1114150A
GB1114150A GB6805/67A GB680567A GB1114150A GB 1114150 A GB1114150 A GB 1114150A GB 6805/67 A GB6805/67 A GB 6805/67A GB 680567 A GB680567 A GB 680567A GB 1114150 A GB1114150 A GB 1114150A
Authority
GB
United Kingdom
Prior art keywords
tocopherol
producing
acid succinate
tocopheryl acid
anhydrous sodium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB6805/67A
Inventor
Tetsuya Nakamura
Shizumasa Kijima
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eisai Co Ltd
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Publication of GB1114150A publication Critical patent/GB1114150A/en
Expired legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B23—MACHINE TOOLS; METAL-WORKING NOT OTHERWISE PROVIDED FOR
    • B23Q—DETAILS, COMPONENTS, OR ACCESSORIES FOR MACHINE TOOLS, e.g. ARRANGEMENTS FOR COPYING OR CONTROLLING; MACHINE TOOLS IN GENERAL CHARACTERISED BY THE CONSTRUCTION OF PARTICULAR DETAILS OR COMPONENTS; COMBINATIONS OR ASSOCIATIONS OF METAL-WORKING MACHINES, NOT DIRECTED TO A PARTICULAR RESULT
    • B23Q16/00—Equipment for precise positioning of tool or work into particular locations not otherwise provided for
    • B23Q16/02—Indexing equipment
    • B23Q16/022—Indexing equipment in which only the indexing movement is of importance
    • B23Q16/025—Indexing equipment in which only the indexing movement is of importance by converting a continuous movement into a rotary indexing movement
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B23—MACHINE TOOLS; METAL-WORKING NOT OTHERWISE PROVIDED FOR
    • B23B—TURNING; BORING
    • B23B39/00—General-purpose boring or drilling machines or devices; Sets of boring and/or drilling machines
    • B23B39/006—Portal drilling machines
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B23—MACHINE TOOLS; METAL-WORKING NOT OTHERWISE PROVIDED FOR
    • B23Q—DETAILS, COMPONENTS, OR ACCESSORIES FOR MACHINE TOOLS, e.g. ARRANGEMENTS FOR COPYING OR CONTROLLING; MACHINE TOOLS IN GENERAL CHARACTERISED BY THE CONSTRUCTION OF PARTICULAR DETAILS OR COMPONENTS; COMBINATIONS OR ASSOCIATIONS OF METAL-WORKING MACHINES, NOT DIRECTED TO A PARTICULAR RESULT
    • B23Q35/00—Control systems or devices for copying directly from a pattern or a master model; Devices for use in copying manually
    • B23Q35/02—Copying discrete points from the pattern, e.g. for determining the position of holes to be drilled
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6
    • C07D311/72—3,4-Dihydro derivatives having in position 2 at least one methyl radical and in position 6 one oxygen atom, e.g. tocopherols

Landscapes

  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Mechanical Engineering (AREA)
  • Automation & Control Theory (AREA)
  • Drilling And Boring (AREA)
  • Pyrane Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

a -Tocopheryl acid succinate is obtained by reacting a -tocopherol with succinic anhydride in the presence of anhydrous sodium acetate, an organic acid and a metal which will react with the organic acid to form hydrogen in the reaction mixture to prevent the oxidation of the a -tocopherol. In examples dl-a -tocopherol and d-a -tocopherol are reacted with succinic anhydride in the presence of anhydrous sodium acetate, acetic acid and zinc.
GB6805/67A 1950-04-11 1967-02-13 Method of producing ª‡-tocopheryl acid succinate Expired GB1114150A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB294415X 1950-04-11

Publications (1)

Publication Number Publication Date
GB1114150A true GB1114150A (en) 1968-05-15

Family

ID=10291604

Family Applications (2)

Application Number Title Priority Date Filing Date
GB8947/50A Expired GB683417A (en) 1950-04-11 1950-04-11 Improvements in automatic drilling, tapping and like machine tools
GB6805/67A Expired GB1114150A (en) 1950-04-11 1967-02-13 Method of producing ª‡-tocopheryl acid succinate

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB8947/50A Expired GB683417A (en) 1950-04-11 1950-04-11 Improvements in automatic drilling, tapping and like machine tools

Country Status (4)

Country Link
CH (1) CH294415A (en)
DE (1) DE882791C (en)
FR (1) FR1035287A (en)
GB (2) GB683417A (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5686632A (en) * 1996-08-14 1997-11-11 Henkel Corporation Method of producing a tocopherol product
WO1998024779A1 (en) * 1996-12-06 1998-06-11 Eastman Chemical Company Process for crystallizing d-alpha-tocopheryl succinate
WO2000010992A2 (en) * 1998-08-24 2000-03-02 Eastman Chemical Company Water-dispersible or water-soluble d-tocotrienol compounds and methods for making therefor
US6130343A (en) * 1995-04-26 2000-10-10 Henkel Corporation Method of producing a tocopherol product
US6139872A (en) * 1996-08-14 2000-10-31 Henkel Corporation Method of producing a vitamin product
CN114195752A (en) * 2022-01-14 2022-03-18 宁波大红鹰生物工程股份有限公司 Environment-friendly d-alpha-tocopherol succinate refining preparation process

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2817901A (en) * 1956-03-12 1957-12-31 Freeman Stephen Thomas Guiding instrument for precision in restorative dental work
FR2314019A1 (en) * 1975-06-13 1977-01-07 Lejeune Sa Automatic dividing head for machine tool - has table driven by worm and air motor with piston actuated locators and hydropneumatic lock
FR2430820A1 (en) * 1978-07-10 1980-02-08 Burth Clement DEVICE FOR DRIVING AND POSITIONING A MACHINE TOOL TRAY PROVIDED WITH A PLURALITY OF WORKSTATIONS
CN107186811A (en) * 2016-03-14 2017-09-22 常州高度新能源科技有限公司 Automatic positioning rotating perforating apparatus
CN112296386A (en) * 2020-11-03 2021-02-02 芜湖同创模具机械有限公司 Drilling equipment is used in automobile punching part processing
CN112475376B (en) * 2020-11-27 2021-12-24 德清县下舍五金机械厂 Processing equipment for automatic claw-taking of paper tube

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6130343A (en) * 1995-04-26 2000-10-10 Henkel Corporation Method of producing a tocopherol product
US5686632A (en) * 1996-08-14 1997-11-11 Henkel Corporation Method of producing a tocopherol product
US6139872A (en) * 1996-08-14 2000-10-31 Henkel Corporation Method of producing a vitamin product
WO1998024779A1 (en) * 1996-12-06 1998-06-11 Eastman Chemical Company Process for crystallizing d-alpha-tocopheryl succinate
WO2000010992A2 (en) * 1998-08-24 2000-03-02 Eastman Chemical Company Water-dispersible or water-soluble d-tocotrienol compounds and methods for making therefor
WO2000010992A3 (en) * 1998-08-24 2000-06-22 Eastman Chem Co Water-dispersible or water-soluble d-tocotrienol compounds and methods for making therefor
CN114195752A (en) * 2022-01-14 2022-03-18 宁波大红鹰生物工程股份有限公司 Environment-friendly d-alpha-tocopherol succinate refining preparation process

Also Published As

Publication number Publication date
GB683417A (en) 1952-11-26
DE882791C (en) 1953-07-13
CH294415A (en) 1953-11-15
FR1035287A (en) 1953-08-20

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