GB1023214A - Carbocyclic hydroxyamines - Google Patents

Carbocyclic hydroxyamines

Info

Publication number
GB1023214A
GB1023214A GB47455/62A GB4745562A GB1023214A GB 1023214 A GB1023214 A GB 1023214A GB 47455/62 A GB47455/62 A GB 47455/62A GB 4745562 A GB4745562 A GB 4745562A GB 1023214 A GB1023214 A GB 1023214A
Authority
GB
United Kingdom
Prior art keywords
formula
alkyl
compound
carbocyclic
reacting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB47455/62A
Other languages
English (en)
Inventor
Marcus Andrew Stevens
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imperial Chemical Industries Ltd
Original Assignee
Imperial Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imperial Chemical Industries Ltd filed Critical Imperial Chemical Industries Ltd
Priority to GB47455/62A priority Critical patent/GB1023214A/en
Priority to US327545A priority patent/US3415873A/en
Priority to DE1963J0024910 priority patent/DE1468092B2/de
Priority to CH246567A priority patent/CH454839A/de
Priority to CH246367A priority patent/CH448072A/de
Priority to CH246267A priority patent/CH445480A/de
Priority to CH246667A priority patent/CH447151A/de
Priority to CH246467A priority patent/CH448073A/de
Priority to CH1530363A priority patent/CH438285A/de
Priority to SE9100/66A priority patent/SE317060B/xx
Priority to BR155455/63A priority patent/BR6355455D0/pt
Priority to SE13996/63A priority patent/SE317058B/xx
Priority to NL63301869A priority patent/NL139232B/xx
Priority to AT293265A priority patent/AT249045B/de
Priority to AT293165A priority patent/AT249039B/de
Priority to AT293365A priority patent/AT256091B/de
Priority to DK586763AA priority patent/DK115695B/da
Priority to FR1558904D priority patent/FR1558904A/fr
Priority to AT1017163A priority patent/AT249042B/de
Priority to FR967601A priority patent/FR3732M/fr
Priority to DK345865AA priority patent/DK123228B/da
Priority to DK345765AA priority patent/DK116202B/da
Priority to DK345965AA priority patent/DK116203B/da
Publication of GB1023214A publication Critical patent/GB1023214A/en
Priority to SE909966A priority patent/SE317059B/xx
Priority to SE910166A priority patent/SE317061B/xx
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C35/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C07C35/22—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system
    • C07C35/23—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system with hydroxy on a condensed ring system having two rings
    • C07C35/36—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system with hydroxy on a condensed ring system having two rings the condensed ring system being a (4.4.0) system, e.g. naphols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB47455/62A 1962-12-17 1962-12-17 Carbocyclic hydroxyamines Expired GB1023214A (en)

Priority Applications (25)

Application Number Priority Date Filing Date Title
GB47455/62A GB1023214A (en) 1962-12-17 1962-12-17 Carbocyclic hydroxyamines
US327545A US3415873A (en) 1962-12-17 1963-12-02 1-amino-3-indanyloxy- and tetrahydro-naphthoxy-2-propanols and the salts thereof
DE1963J0024910 DE1468092B2 (de) 1962-12-17 1963-12-11 Aminopropoxy-derivate des tetrahydronaphthalins und des indans, deren saeureadditionssalze, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische praeparate
CH246567A CH454839A (de) 1962-12-17 1963-12-13 Verfahren zur Herstellung homocyclischer Verbindungen
CH246367A CH448072A (de) 1962-12-17 1963-12-13 Verfahren zur Herstellung homocyclischer Verbindungen
CH246267A CH445480A (de) 1962-12-17 1963-12-13 Verfahren zur Herstellung homocyclischer Verbindungen
CH246667A CH447151A (de) 1962-12-17 1963-12-13 Verfahren zur Herstellung homocyclischer Verbindungen
CH246467A CH448073A (de) 1962-12-17 1963-12-13 Verfahren zur Herstellung homocyclischer Verbindungen
CH1530363A CH438285A (de) 1962-12-17 1963-12-13 Verfahren zur Herstellung homocyclischer Verbindungen
SE9100/66A SE317060B (en:Method) 1962-12-17 1963-12-16
BR155455/63A BR6355455D0 (pt) 1962-12-17 1963-12-16 Processo para a fabricacao de novos compostos homociclicos derivados de tetraidronaftaleno e indano
SE13996/63A SE317058B (en:Method) 1962-12-17 1963-12-16
NL63301869A NL139232B (nl) 1962-12-17 1963-12-16 Werkwijze voor het bereiden van farmaceutische preparaten met een de beta-adrenergische werking blokkerende werking.
AT293265A AT249045B (de) 1962-12-17 1963-12-17 Verfahren zur Herstellung von neuen Indan- und Tetrahydronaphthalin-Verbindungen und deren Salzen
AT293165A AT249039B (de) 1962-12-17 1963-12-17 Verfahren zur Herstellung von neuen Tetrahydronaphthalin-Verbindungen und deren Salzen
AT293365A AT256091B (de) 1962-12-17 1963-12-17 Verfahren zur Herstellung von neuen Indan- und Tetrahydronaphthalin-Verbindungen und deren Salzen
DK586763AA DK115695B (da) 1962-12-17 1963-12-17 Fremgangsmåde til fremstilling af basiske ethere af indan eller tetrahydronaphthalen eller syreadditionssalte deraf.
FR1558904D FR1558904A (en:Method) 1962-12-17 1963-12-17
AT1017163A AT249042B (de) 1962-12-17 1963-12-17 Verfahren zur Herstellung von neuen Indan- bzw. Tetrahydronaphthalin-Verbindungen und deren Salzen
FR967601A FR3732M (fr) 1962-12-17 1964-03-16 Nouveaux dérivés du tétrahydro-naphtalene et de l'indane.
DK345865AA DK123228B (da) 1962-12-17 1965-07-07 Analogifremgangsmåde til fremstilling af basiske ethere af indan eller tetrahydronaphthalen eller syreadditionssalte deraf.
DK345765AA DK116202B (da) 1962-12-17 1965-07-07 Fremgangsmåde til fremstilling af basiske ethere af indan eller tetrahydronaphthalen eller syreadditionssalte deraf.
DK345965AA DK116203B (da) 1962-12-17 1965-07-07 Fremgangsmåde til fremstilling af basiske ethere af tetrahydronaphthalen eller syreadditionssalte deraf.
SE909966A SE317059B (en:Method) 1962-12-17 1966-07-04
SE910166A SE317061B (en:Method) 1962-12-17 1966-07-04

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB47455/62A GB1023214A (en) 1962-12-17 1962-12-17 Carbocyclic hydroxyamines

Publications (1)

Publication Number Publication Date
GB1023214A true GB1023214A (en) 1966-03-23

Family

ID=10445031

Family Applications (1)

Application Number Title Priority Date Filing Date
GB47455/62A Expired GB1023214A (en) 1962-12-17 1962-12-17 Carbocyclic hydroxyamines

Country Status (9)

Country Link
US (1) US3415873A (en:Method)
AT (4) AT249042B (en:Method)
BR (1) BR6355455D0 (en:Method)
CH (6) CH448073A (en:Method)
DE (1) DE1468092B2 (en:Method)
DK (4) DK115695B (en:Method)
FR (2) FR1558904A (en:Method)
GB (1) GB1023214A (en:Method)
SE (3) SE317060B (en:Method)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1950742A1 (de) * 1968-10-16 1970-04-30 Squibb & Sons Inc 5,8-Dihydronaphthyloxy-amino-propanolverbindungen und Verfahren zu ihrer Herstellung
FR2018626A1 (en:Method) * 1968-09-23 1970-06-26 Warner Lambert Pharmaceutical
EP0003664A1 (en) * 1978-02-08 1979-08-22 Imperial Chemical Industries Plc Alkanolamine derivatives, process for their preparation and pharmaceutical compositions containing them
US4435426A (en) 1981-06-05 1984-03-06 Societe Anonyme Dite: Sanofi Ethers of phenol active on the cardiovascular system, process for preparing same and use thereof in drugs
GB2165835A (en) * 1984-07-30 1986-04-23 Ici Plc Alkanolamine derivatives

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL300886A (en:Method) * 1962-11-23
US3855296A (en) * 1968-04-29 1974-12-17 Sandoz Ag CYCLO-SUBSTITUTED-1-p({107 -AMINOALKOXY) PHENYL CYCLOHEXANES
US3534086A (en) * 1968-10-16 1970-10-13 Squibb & Sons Inc Adamantylamino - 5,8 - dihydronaphthyloxypropanols and related compounds
US4127675A (en) * 1968-11-12 1978-11-28 Yamanouchi Pharmaceutical Co., Ltd. 4-(Alkylamino-2-hydroxypropoxy)-indenes and method of use
US4045482A (en) * 1968-11-12 1977-08-30 Yamanouchi Pharmaceutical Co. Ltd. 4-(3-Isopropylamino-2-hydroxypropoxy indene
US4360464A (en) * 1969-11-28 1982-11-23 Teikoku Hormone Mfg. Co. Ltd. Process for production of 1-aryloxy-aminopropane derivatives
DE2130393C3 (de) * 1970-06-22 1981-02-26 E.R. Squibb & Sons Inc., New York, N.Y. (V.St.A.) 6,7-Dihydroxy -5,6,7,8-tetrahydronaphthyloxyaminopropanole und ihre Salze mit Säuren sowie ihre Verwendung bei der Bekämpfung von Herzerkrankungen
US3671530A (en) * 1970-08-27 1972-06-20 Miles Lab Certain substituted 1,3-bisdilower-alkylaminoethoxy-indans
FR2119844B1 (en:Method) * 1970-12-28 1974-03-22 Laroche Navarro Labo
US3758583A (en) * 1971-01-21 1973-09-11 Syntex Corp 2-(2-hydroxy-3-aminopropyl-1-yloxy)-1,6-dilfuoro-and-1,6-methano-{8 10{9 annulenes and the salts thereof
CH580057A5 (en:Method) * 1973-04-17 1976-09-30 Ciba Geigy Ag
US4897355A (en) * 1985-01-07 1990-01-30 Syntex (U.S.A.) Inc. N[ω,(ω-1)-dialkyloxy]- and N-[ω,(ω-1)-dialkenyloxy]-alk-1-yl-N,N,N-tetrasubstituted ammonium lipids and uses therefor
US5550289A (en) * 1985-01-07 1996-08-27 Syntex (U.S.A.) Inc. N-(1,(1-1)-dialkyloxy)-and N-(1,(1-1)-dialkenyloxy alk-1-yl-N-N,N-tetrasubstituted ammonium lipids and uses therefor
US5013761A (en) * 1988-06-03 1991-05-07 Eli Lilly And Company Serotonin antagonists

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2835669A (en) * 1958-05-20 Process for the production of substi-
US2033640A (en) * 1933-12-23 1936-03-10 Edward W Mears Container
US2817675A (en) * 1951-12-07 1957-12-24 Saul & Co Basic condensation products containing nitrogen
US2681932A (en) * 1952-01-23 1954-06-22 Searle & Co Lower dialkylaminoalkyl ethers of 1, 2, 3, 4-tetrahydronaphthalene and salts thereof
US3051709A (en) * 1960-04-22 1962-08-28 Us Vitamin Pharm Corp Substitutedamino-3-(4-and 5-indanoxy)-propane-2-ols
US3234211A (en) * 1962-10-24 1966-02-08 Ciba Geigy Corp Tertiaryaminoalkoxy alkylene monocyclic carbocyclic aryltetrahydro naphthalenes, indanes, indenes and homologs thereof

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2018626A1 (en:Method) * 1968-09-23 1970-06-26 Warner Lambert Pharmaceutical
DE1950742A1 (de) * 1968-10-16 1970-04-30 Squibb & Sons Inc 5,8-Dihydronaphthyloxy-amino-propanolverbindungen und Verfahren zu ihrer Herstellung
EP0003664A1 (en) * 1978-02-08 1979-08-22 Imperial Chemical Industries Plc Alkanolamine derivatives, process for their preparation and pharmaceutical compositions containing them
US4435426A (en) 1981-06-05 1984-03-06 Societe Anonyme Dite: Sanofi Ethers of phenol active on the cardiovascular system, process for preparing same and use thereof in drugs
GB2165835A (en) * 1984-07-30 1986-04-23 Ici Plc Alkanolamine derivatives

Also Published As

Publication number Publication date
CH447151A (de) 1967-11-30
SE317061B (en:Method) 1969-11-10
CH448072A (de) 1967-12-15
AT249042B (de) 1966-08-25
US3415873A (en) 1968-12-10
CH438285A (de) 1967-06-30
SE317060B (en:Method) 1969-11-10
DK116203B (da) 1969-12-22
FR3732M (fr) 1965-12-06
AT256091B (de) 1967-08-10
AT249039B (de) 1966-08-25
BR6355455D0 (pt) 1973-08-09
CH448073A (de) 1967-12-15
DE1468092A1 (de) 1968-12-05
DE1468092B2 (de) 1976-07-22
FR1558904A (en:Method) 1969-03-07
SE317059B (en:Method) 1969-11-10
AT249045B (de) 1966-08-25
CH454839A (de) 1968-04-30
DK123228B (da) 1972-05-29
DK116202B (da) 1969-12-22
CH445480A (de) 1967-10-31
DK115695B (da) 1969-11-03

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