GB1020611A - Thenylguanidines, the preparation thereof, and pharmaceutical compositions containinghem - Google Patents
Thenylguanidines, the preparation thereof, and pharmaceutical compositions containinghemInfo
- Publication number
- GB1020611A GB1020611A GB14275/61A GB1427561A GB1020611A GB 1020611 A GB1020611 A GB 1020611A GB 14275/61 A GB14275/61 A GB 14275/61A GB 1427561 A GB1427561 A GB 1427561A GB 1020611 A GB1020611 A GB 1020611A
- Authority
- GB
- United Kingdom
- Prior art keywords
- methyl
- group
- thenyl
- reacting
- hydrogen atom
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 7
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- XZMCDFZZKTWFGF-UHFFFAOYSA-N Cyanamide Chemical compound NC#N XZMCDFZZKTWFGF-UHFFFAOYSA-N 0.000 abstract 3
- -1 S-substituted isothiourea Chemical class 0.000 abstract 3
- 125000004432 carbon atom Chemical group C* 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 150000002357 guanidines Chemical class 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 3
- LGDSHSYDSCRFAB-UHFFFAOYSA-N Methyl isothiocyanate Chemical compound CN=C=S LGDSHSYDSCRFAB-UHFFFAOYSA-N 0.000 abstract 2
- CHJJGSNFBQVOTG-UHFFFAOYSA-N N-methyl-guanidine Natural products CNC(N)=N CHJJGSNFBQVOTG-UHFFFAOYSA-N 0.000 abstract 2
- 150000001412 amines Chemical class 0.000 abstract 2
- 229910021529 ammonia Inorganic materials 0.000 abstract 2
- ZRALSGWEFCBTJO-UHFFFAOYSA-N anhydrous guanidine Natural products NC(N)=N ZRALSGWEFCBTJO-UHFFFAOYSA-N 0.000 abstract 2
- SWSQBOPZIKWTGO-UHFFFAOYSA-N dimethylaminoamidine Natural products CN(C)C(N)=N SWSQBOPZIKWTGO-UHFFFAOYSA-N 0.000 abstract 2
- FKKJJPMGAWGYPN-UHFFFAOYSA-N thiophen-2-ylmethanamine Chemical compound NCC1=CC=CS1 FKKJJPMGAWGYPN-UHFFFAOYSA-N 0.000 abstract 2
- UMGDCJDMYOKAJW-UHFFFAOYSA-N thiourea Chemical compound NC(N)=S UMGDCJDMYOKAJW-UHFFFAOYSA-N 0.000 abstract 2
- SWZNXCABBUKIPZ-UHFFFAOYSA-N (3-methylthiophen-2-yl)methanamine Chemical compound CC=1C=CSC=1CN SWZNXCABBUKIPZ-UHFFFAOYSA-N 0.000 abstract 1
- IWWLIIWFFOOKRR-UHFFFAOYSA-N 1-methyl-1-(thiophen-2-ylmethyl)thiourea Chemical compound NC(=S)N(C)CC1=CC=CS1 IWWLIIWFFOOKRR-UHFFFAOYSA-N 0.000 abstract 1
- BIWSWIRUDKFWIR-UHFFFAOYSA-N 1-methyl-1-[(3-methylthiophen-2-yl)methyl]thiourea Chemical compound CN(C(=S)N)CC1=C(C=CS1)C BIWSWIRUDKFWIR-UHFFFAOYSA-N 0.000 abstract 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Natural products NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000004429 atom Chemical group 0.000 abstract 1
- 239000002775 capsule Substances 0.000 abstract 1
- 239000008187 granular material Substances 0.000 abstract 1
- INQOMBQAUSQDDS-UHFFFAOYSA-N iodomethane Chemical compound IC INQOMBQAUSQDDS-UHFFFAOYSA-N 0.000 abstract 1
- CIYBBEUYSUUEHQ-UHFFFAOYSA-N methyl N-methyl-N-(thiophen-2-ylmethyl)carbamimidothioate Chemical compound CN(C(SC)=N)CC1=CC=CS1 CIYBBEUYSUUEHQ-UHFFFAOYSA-N 0.000 abstract 1
- KLWZSMGUCTWZKL-UHFFFAOYSA-N methyl N-methyl-N-[(3-methylthiophen-2-yl)methyl]carbamimidothioate hydroiodide Chemical compound I.CN(C(SC)=N)CC1=C(C=CS1)C KLWZSMGUCTWZKL-UHFFFAOYSA-N 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 210000005036 nerve Anatomy 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 150000003141 primary amines Chemical class 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 150000003335 secondary amines Chemical class 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 239000000829 suppository Substances 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
- 230000002889 sympathetic effect Effects 0.000 abstract 1
- 239000003826 tablet Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D281/18—Eight-membered rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK177462AA DK104988C (da) | 1961-04-20 | 1962-04-17 | Fremgangsmåde til fremstilling af thenylguanidiner eller syreadditionssalte heraf. |
| FR894767A FR1826M (fr) | 1961-04-20 | 1962-04-17 | Médicament a base d'un dérivé de la guanidine. |
| US188544A US3242194A (en) | 1961-04-20 | 1962-04-18 | Thenyl guanidines |
| CH480462A CH459258A (de) | 1961-04-20 | 1962-04-18 | Verfahren zur Herstellung von Guanidinen |
| SE4471/62A SE304013B (enrdf_load_stackoverflow) | 1961-04-20 | 1962-04-19 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEF39883A DE1217958B (de) | 1963-05-31 | 1963-05-31 | Verfahren zur Herstellung von 11, 12-Dihydro-6H-dibenzo[b, f]-[1, 4] thiazocinen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1020611A true GB1020611A (en) | 1966-02-23 |
Family
ID=7097992
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB14275/61A Expired GB1020611A (en) | 1961-04-20 | 1961-04-20 | Thenylguanidines, the preparation thereof, and pharmaceutical compositions containinghem |
Country Status (2)
| Country | Link |
|---|---|
| GB (1) | GB1020611A (enrdf_load_stackoverflow) |
| NL (2) | NL125059C (enrdf_load_stackoverflow) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2210616A (en) * | 1987-10-02 | 1989-06-14 | Egyt Gyogyszervegyeszeti Gyar | (2-Thienyl-methyl)-thiourea derivatives |
-
0
- NL NL277326D patent/NL277326A/xx unknown
- NL NL125059D patent/NL125059C/xx active
-
1961
- 1961-04-20 GB GB14275/61A patent/GB1020611A/en not_active Expired
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2210616A (en) * | 1987-10-02 | 1989-06-14 | Egyt Gyogyszervegyeszeti Gyar | (2-Thienyl-methyl)-thiourea derivatives |
| AU607811B2 (en) * | 1987-10-02 | 1991-03-14 | Egis Gyogyszergyar | (2-thienyl-methyl)-thiourea derivatives |
| GB2210616B (en) * | 1987-10-02 | 1991-03-27 | Egyt Gyogyszervegyeszeti Gyar | (2-thienyl-methyl)-thiourea derivatives |
Also Published As
| Publication number | Publication date |
|---|---|
| NL277326A (enrdf_load_stackoverflow) | |
| NL125059C (enrdf_load_stackoverflow) |
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