GB0031302D0 - Napthalene derivatives - Google Patents
Napthalene derivativesInfo
- Publication number
- GB0031302D0 GB0031302D0 GBGB0031302.3A GB0031302A GB0031302D0 GB 0031302 D0 GB0031302 D0 GB 0031302D0 GB 0031302 A GB0031302 A GB 0031302A GB 0031302 D0 GB0031302 D0 GB 0031302D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- derivatives
- napthalene
- napthalene derivatives
- neurodegenerative
- immunological
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- UFWIBTONFRDIAS-UHFFFAOYSA-N Naphthalene Chemical class C1=CC=CC2=CC=CC=C21 UFWIBTONFRDIAS-UHFFFAOYSA-N 0.000 title 1
- 208000020084 Bone disease Diseases 0.000 abstract 1
- 101150109738 Ptger4 gene Proteins 0.000 abstract 1
- 208000027520 Somatoform disease Diseases 0.000 abstract 1
- 210000000988 bone and bone Anatomy 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000001900 immune effect Effects 0.000 abstract 1
- 208000026278 immune system disease Diseases 0.000 abstract 1
- 208000027866 inflammatory disease Diseases 0.000 abstract 1
- 230000002757 inflammatory effect Effects 0.000 abstract 1
- 208000017169 kidney disease Diseases 0.000 abstract 1
- 208000015122 neurodegenerative disease Diseases 0.000 abstract 1
- 230000000626 neurodegenerative effect Effects 0.000 abstract 1
- 230000036407 pain Effects 0.000 abstract 1
- 208000027753 pain disease Diseases 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/58—[b]- or [c]-condensed
- C07D209/62—Naphtho [c] pyrroles; Hydrogenated naphtho [c] pyrroles
- C07D209/64—Naphtho [c] pyrroles; Hydrogenated naphtho [c] pyrroles with an oxygen atom in position 1
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/58—[b]- or [c]-condensed
- C07D209/62—Naphtho [c] pyrroles; Hydrogenated naphtho [c] pyrroles
- C07D209/66—Naphtho [c] pyrroles; Hydrogenated naphtho [c] pyrroles with oxygen atoms in positions 1 and 3
Landscapes
- Health & Medical Sciences (AREA)
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Priority Applications (9)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0031302.3A GB0031302D0 (en) | 2000-12-21 | 2000-12-21 | Napthalene derivatives |
| AT01271355T ATE371645T1 (de) | 2000-12-21 | 2001-12-20 | Naphthalinderivate, die sich an den ep4?rezeptor binden |
| US10/450,891 US6924297B2 (en) | 2000-12-21 | 2001-12-20 | Naphathalene derivatives which bind to the EP4 receptor |
| PCT/GB2001/005676 WO2002050032A1 (en) | 2000-12-21 | 2001-12-20 | Naphthalene derivatives which bind to the ep4 receptor |
| EP01271355A EP1351934B1 (en) | 2000-12-21 | 2001-12-20 | Naphthalene derivatives which bind to the ep4 receptor |
| ES01271355T ES2290093T3 (es) | 2000-12-21 | 2001-12-20 | Derivados de naftaleno que se unen al receptor ep4. |
| JP2002551529A JP4397586B2 (ja) | 2000-12-21 | 2001-12-20 | Ep4受容体に結合するナフタレン誘導体 |
| AU2002216218A AU2002216218A1 (en) | 2000-12-21 | 2001-12-20 | Naphthalene derivatives which bind to the ep4 receptor |
| DE60130256T DE60130256T2 (de) | 2000-12-21 | 2001-12-20 | Naphthalinderivate, die sich an den ep4?rezeptor binden |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0031302.3A GB0031302D0 (en) | 2000-12-21 | 2000-12-21 | Napthalene derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB0031302D0 true GB0031302D0 (en) | 2001-01-31 |
Family
ID=9905630
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GBGB0031302.3A Ceased GB0031302D0 (en) | 2000-12-21 | 2000-12-21 | Napthalene derivatives |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6924297B2 (enExample) |
| EP (1) | EP1351934B1 (enExample) |
| JP (1) | JP4397586B2 (enExample) |
| AT (1) | ATE371645T1 (enExample) |
| AU (1) | AU2002216218A1 (enExample) |
| DE (1) | DE60130256T2 (enExample) |
| ES (1) | ES2290093T3 (enExample) |
| GB (1) | GB0031302D0 (enExample) |
| WO (1) | WO2002050032A1 (enExample) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HN2001000224A (es) | 2000-10-19 | 2002-06-13 | Pfizer | Compuestos de imidazol condensado con arilo o heteroarilo como agentes anti - inflamatorios y analgesicos. |
| GB0031295D0 (en) * | 2000-12-21 | 2001-01-31 | Glaxo Group Ltd | Naphthalene derivatives |
| US20090036495A1 (en) * | 2004-04-20 | 2009-02-05 | Pfizer, Inc. | Combinations Comprising Alpha-2-Delta Ligands and Ep4 Receptor Antagonists |
| JP5289046B2 (ja) * | 2005-05-19 | 2013-09-11 | メルク カナダ インコーポレイテッド | Ep4アンタゴニストとしてのキノリン誘導体 |
| UY30121A1 (es) | 2006-02-03 | 2007-08-31 | Glaxo Group Ltd | Nuevos compuestos |
| GB0615111D0 (en) * | 2006-07-28 | 2006-09-06 | Glaxo Group Ltd | Novel compounds |
| GB0615105D0 (en) | 2006-07-28 | 2006-09-06 | Glaxo Group Ltd | Novel compounds |
| CA2672631A1 (en) | 2006-12-15 | 2008-06-19 | Glaxo Group Limited | Benzamide derivatives as ep4 receptor agonists |
| CN101636385B (zh) * | 2007-03-26 | 2012-09-05 | 默克弗罗斯特加拿大有限公司 | 作为ep4受体拮抗剂的萘和喹啉磺酰脲衍生物 |
| GB0721611D0 (en) | 2007-11-02 | 2007-12-12 | Glaxo Group Ltd | Novel compounds |
| EP2149551A1 (de) | 2008-07-30 | 2010-02-03 | Bayer Schering Pharma AG | N-(Indol-3-ylalkyl)-(hetero)arylamidderivate als Modulatoren des EP2-Rezeptors |
| EP2149554A1 (de) | 2008-07-30 | 2010-02-03 | Bayer Schering Pharma Aktiengesellschaft | Indolylamide als Modulatoren des EP2-Rezeptors |
| EP2149552A1 (de) | 2008-07-30 | 2010-02-03 | Bayer Schering Pharma AG | 5,6 substituierte Benzamid-Derivate als Modulatoren des EP2-Rezeptors |
| WO2010087425A1 (ja) | 2009-01-30 | 2010-08-05 | 国立大学法人京都大学 | 前立腺癌の進行抑制剤および進行抑制方法 |
| DE102009049662A1 (de) | 2009-10-13 | 2011-04-14 | Bayer Schering Pharma Aktiengesellschaft | 2,5-Disubstituierte 2H-Indazole als EP2-Rezeptor-Antagonisten |
| JP2013508282A (ja) | 2009-10-14 | 2013-03-07 | ジェンムス ファーマ インコーポレイティド | ウイルス感染のための併用療法処置 |
| AU2014305843B2 (en) | 2013-08-09 | 2019-08-29 | Ardelyx, Inc. | Compounds and methods for inhibiting phosphate transport |
| CN111039916B (zh) * | 2015-01-09 | 2023-04-28 | 小野药品工业株式会社 | 三环螺环化合物 |
| CR20180323A (es) | 2015-11-20 | 2018-08-06 | Idorsia Pharmaceuticals Ltd | Derivados de indol n-sustituídos como moduladores de los receptores de pge2 |
| JP6269888B1 (ja) * | 2016-07-07 | 2018-01-31 | 小野薬品工業株式会社 | 医薬用途 |
| US11325899B2 (en) | 2017-05-18 | 2022-05-10 | Idorsia Pharmaceuticals Ltd | Benzofurane and benzothiophene derivatives as PGE2 receptor modulators |
| AR111808A1 (es) | 2017-05-18 | 2019-08-21 | Idorsia Pharmaceuticals Ltd | Derivados de pirimidina como moduladores del receptor de pge2 |
| HRP20211533T1 (hr) | 2017-05-18 | 2022-01-07 | Idorsia Pharmaceuticals Ltd | Derivati fenila kao modulatori receptora pge2 |
| ES2896476T3 (es) | 2017-05-18 | 2022-02-24 | Idorsia Pharmaceuticals Ltd | Derivados de pirimidina |
| TWI768043B (zh) | 2017-05-18 | 2022-06-21 | 瑞士商愛杜西亞製藥有限公司 | N-取代吲哚衍生物 |
| EP3759073A1 (en) | 2018-03-02 | 2021-01-06 | Inflazome Limited | Sulfonamide derivates as nlrp3 inhibitors |
| WO2019166628A1 (en) | 2018-03-02 | 2019-09-06 | Inflazome Limited | Novel compounds |
| WO2019166627A1 (en) | 2018-03-02 | 2019-09-06 | Inflazome Limited | Novel compounds |
| US11530200B2 (en) | 2018-03-02 | 2022-12-20 | Inflazome Limited | Compounds |
| WO2019166629A1 (en) | 2018-03-02 | 2019-09-06 | Inflazome Limited | Novel compounds |
| US20200368223A1 (en) | 2019-05-21 | 2020-11-26 | Ardelyx, Inc. | Methods for inhibiting phosphate transport |
| KR20230107228A (ko) | 2020-11-13 | 2023-07-14 | 오노 야꾸힝 고교 가부시키가이샤 | Ep4 길항약과 면역 체크포인트 저해 물질의 병용에 의한 암 치료 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4014899A (en) * | 1973-10-29 | 1977-03-29 | Ciba-Geigy Corporation | 5,6-Benzoisoindolines |
| US4395417A (en) * | 1980-04-22 | 1983-07-26 | Research Corporation | Antihyperlipidemic compositions |
| ID18046A (id) * | 1996-08-20 | 1998-02-19 | Takeda Chemical Industries Ltd | Senyawa siklik campuran, pembuatan dan penngunaannya. |
| DE19650975A1 (de) | 1996-12-09 | 1998-06-10 | Basf Ag | Neue heterocyclisch substituierte Benzamide und deren Anwendung |
| ES2223531T3 (es) * | 1999-06-10 | 2005-03-01 | Warner-Lambert Company Llc | Metodo de inhibir la agregacion de proteinas amiloides y de formacion de imagenes de depositos amiloides usando derivados de isoindolina. |
-
2000
- 2000-12-21 GB GBGB0031302.3A patent/GB0031302D0/en not_active Ceased
-
2001
- 2001-12-20 AT AT01271355T patent/ATE371645T1/de not_active IP Right Cessation
- 2001-12-20 WO PCT/GB2001/005676 patent/WO2002050032A1/en not_active Ceased
- 2001-12-20 ES ES01271355T patent/ES2290093T3/es not_active Expired - Lifetime
- 2001-12-20 US US10/450,891 patent/US6924297B2/en not_active Expired - Fee Related
- 2001-12-20 AU AU2002216218A patent/AU2002216218A1/en not_active Abandoned
- 2001-12-20 JP JP2002551529A patent/JP4397586B2/ja not_active Expired - Fee Related
- 2001-12-20 DE DE60130256T patent/DE60130256T2/de not_active Expired - Lifetime
- 2001-12-20 EP EP01271355A patent/EP1351934B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US6924297B2 (en) | 2005-08-02 |
| DE60130256T2 (de) | 2008-05-21 |
| JP2004517099A (ja) | 2004-06-10 |
| EP1351934B1 (en) | 2007-08-29 |
| ATE371645T1 (de) | 2007-09-15 |
| AU2002216218A1 (en) | 2002-07-01 |
| WO2002050032A1 (en) | 2002-06-27 |
| EP1351934A1 (en) | 2003-10-15 |
| ES2290093T3 (es) | 2008-02-16 |
| DE60130256D1 (de) | 2007-10-11 |
| JP4397586B2 (ja) | 2010-01-13 |
| US20040102508A1 (en) | 2004-05-27 |
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| AT | Applications terminated before publication under section 16(1) |