FR3104945B3 - Hydrogel à base d’un dérivé hydroxyphényle réticulé d’acide hyaluronique - Google Patents
Hydrogel à base d’un dérivé hydroxyphényle réticulé d’acide hyaluronique Download PDFInfo
- Publication number
- FR3104945B3 FR3104945B3 FR2009046A FR2009046A FR3104945B3 FR 3104945 B3 FR3104945 B3 FR 3104945B3 FR 2009046 A FR2009046 A FR 2009046A FR 2009046 A FR2009046 A FR 2009046A FR 3104945 B3 FR3104945 B3 FR 3104945B3
- Authority
- FR
- France
- Prior art keywords
- hyaluronic acid
- crosslinked
- hydrogel based
- hydroxyphenyl derivative
- hydroxyphenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 229920002674 hyaluronan Polymers 0.000 title abstract 5
- 229960003160 hyaluronic acid Drugs 0.000 title abstract 5
- 125000004464 hydroxyphenyl group Chemical group 0.000 title abstract 4
- 239000000017 hydrogel Substances 0.000 title abstract 3
- 150000003839 salts Chemical class 0.000 abstract 3
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 abstract 1
- SQDAZGGFXASXDW-UHFFFAOYSA-N 5-bromo-2-(trifluoromethoxy)pyridine Chemical compound FC(F)(F)OC1=CC=C(Br)C=N1 SQDAZGGFXASXDW-UHFFFAOYSA-N 0.000 abstract 1
- 229920001287 Chondroitin sulfate Polymers 0.000 abstract 1
- 150000001447 alkali salts Chemical class 0.000 abstract 1
- 229940059329 chondroitin sulfate Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J3/00—Processes of treating or compounding macromolecular substances
- C08J3/02—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques
- C08J3/03—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in aqueous media
- C08J3/075—Macromolecular gels
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0069—Chondroitin-4-sulfate, i.e. chondroitin sulfate A; Dermatan sulfate, i.e. chondroitin sulfate B or beta-heparin; Chondroitin-6-sulfate, i.e. chondroitin sulfate C; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L101/00—Compositions of unspecified macromolecular compounds
- C08L101/12—Compositions of unspecified macromolecular compounds characterised by physical features, e.g. anisotropy, viscosity or electrical conductivity
- C08L101/14—Compositions of unspecified macromolecular compounds characterised by physical features, e.g. anisotropy, viscosity or electrical conductivity the macromolecular compounds being water soluble or water swellable, e.g. aqueous gels
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
- C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2305/00—Characterised by the use of polysaccharides or of their derivatives not provided for in groups C08J2301/00 or C08J2303/00
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Materials Engineering (AREA)
- Dispersion Chemistry (AREA)
- Dermatology (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Materials For Medical Uses (AREA)
- Cosmetics (AREA)
- Medicinal Preparation (AREA)
Abstract
Hydrogel à base d’un dérivé hydroxyphényle réticulé d’acide hyaluronique La présente invention concerne un hydrogel à base d’un dérivé hydroxyphényle réticulé de l’acide hyaluronique, caractérisé en ce qu’il contient des molécules d’un dérivé hydroxyphényle de l’acide hyaluronique (HA-TA), ou du sel pharmaceutiquement acceptable de celui-ci, et du sulfate de chondroïtine, ou du sel de celui-ci pharmaceutiquement acceptable, sélectionné dans un groupe comprenant des sels alcalins ou des sels alcalino-terreux.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CZ2019-36602U CZ33324U1 (cs) | 2019-09-06 | 2019-09-06 | Hydrogel na bázi zesíťovaného hydroxyfenylového derivátu kyseliny hyaluronové |
CZPUV2019-36602 | 2019-09-06 |
Publications (2)
Publication Number | Publication Date |
---|---|
FR3104945A3 FR3104945A3 (fr) | 2021-06-25 |
FR3104945B3 true FR3104945B3 (fr) | 2021-12-10 |
Family
ID=68384244
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR2009046A Active FR3104945B3 (fr) | 2019-09-06 | 2020-09-07 | Hydrogel à base d’un dérivé hydroxyphényle réticulé d’acide hyaluronique |
Country Status (6)
Country | Link |
---|---|
AT (1) | AT18104U1 (fr) |
CZ (1) | CZ33324U1 (fr) |
DE (1) | DE212020000715U1 (fr) |
FR (1) | FR3104945B3 (fr) |
SK (1) | SK9649Y1 (fr) |
WO (1) | WO2021043349A1 (fr) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CZ308970B6 (cs) * | 2020-05-12 | 2021-10-27 | Contipro A.S. | Sada gelotvorných roztoků určená pro přípravu hydrogelu na bázi kovalentně zesítěného hydroxyfenylového derivátu hyaluronanu k prevenci pooperačních komplikací souvisejících s vytvořením kolorektální anastomózy a její použití |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU555747B2 (en) | 1983-08-09 | 1986-10-09 | Cilco Inc. | Chondroitin sulfate and sodium hyaluronate composition |
US6051560A (en) | 1986-06-26 | 2000-04-18 | Nestle S.A. | Chrondroitin sulfate/sodium hyaluronate composition |
DE10156617A1 (de) | 2001-11-17 | 2003-05-28 | Biosphings Ag | Herstellung reiner Stereoisomere von Tricyclo[5.2.1.0··2··.··6··]-dec-9-yl-xanthogenat und Arzneimittel daraus |
ATE525076T1 (de) | 2002-10-16 | 2011-10-15 | Arthrodynamic Technologies Animal Health Division Inc | Behandlung von traumatischer synovitis und geschädigtem gelenkknorpel |
US6982298B2 (en) | 2003-01-10 | 2006-01-03 | The Cleveland Clinic Foundation | Hydroxyphenyl cross-linked macromolecular network and applications thereof |
US7465766B2 (en) * | 2004-01-08 | 2008-12-16 | The Cleveland Clinic Foundation | Hydroxyphenyl cross-linked macromolecular network and applications thereof |
CN101052684B (zh) | 2004-07-09 | 2014-02-12 | 克利夫兰临床基金会 | 羟基苯交联大分子网络及其应用 |
US8394782B2 (en) | 2007-11-30 | 2013-03-12 | Allergan, Inc. | Polysaccharide gel formulation having increased longevity |
KR101091028B1 (ko) * | 2009-07-02 | 2011-12-09 | 아주대학교산학협력단 | 체내 주입형 하이드로젤 및 이의 생의학적 용도 |
KR101161640B1 (ko) * | 2009-08-25 | 2012-07-02 | 서울과학기술대학교 산학협력단 | 리포산이 결합된 화합물과 이의 제조방법 |
EP3067069B1 (fr) * | 2009-11-11 | 2023-07-26 | Hy2Care B.V. | Hydrogels à base de polymères de dextrane-tyramine et conjugués tyramine de polymères naturels |
CZ28434U1 (cs) * | 2015-05-18 | 2015-07-07 | Contipro Biotech S.R.O. | Nanokompozit na bázi hydroxyfenylového derivátu kyseliny hyaluronové nebo jejísoli obsahující nanočástice fosforečnanu vápenatého |
-
2019
- 2019-09-06 CZ CZ2019-36602U patent/CZ33324U1/cs active Protection Beyond IP Right Term
-
2020
- 2020-09-03 DE DE212020000715.2U patent/DE212020000715U1/de active Active
- 2020-09-03 SK SK50027-2022U patent/SK9649Y1/sk unknown
- 2020-09-03 AT ATGM9011/2020U patent/AT18104U1/de unknown
- 2020-09-03 WO PCT/CZ2020/050065 patent/WO2021043349A1/fr active Application Filing
- 2020-09-07 FR FR2009046A patent/FR3104945B3/fr active Active
Also Published As
Publication number | Publication date |
---|---|
WO2021043349A1 (fr) | 2021-03-11 |
SK9649Y1 (sk) | 2022-11-24 |
CZ33324U1 (cs) | 2019-10-25 |
SK500272022U1 (sk) | 2022-07-27 |
FR3104945A3 (fr) | 2021-06-25 |
DE212020000715U1 (de) | 2022-04-21 |
AT18104U1 (de) | 2024-02-15 |
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