FR3053968A1 - Reactifs pour la protection reversible de molecules biologiques - Google Patents
Reactifs pour la protection reversible de molecules biologiques Download PDFInfo
- Publication number
- FR3053968A1 FR3053968A1 FR1656791A FR1656791A FR3053968A1 FR 3053968 A1 FR3053968 A1 FR 3053968A1 FR 1656791 A FR1656791 A FR 1656791A FR 1656791 A FR1656791 A FR 1656791A FR 3053968 A1 FR3053968 A1 FR 3053968A1
- Authority
- FR
- France
- Prior art keywords
- group
- substituted
- biological molecule
- unsubstituted
- protected
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- UTFRNYFMGIEIJU-UHFFFAOYSA-N CC(C)(C)OC(NCc(c(I)cnc1N(C)C(O)O2)c1C2=O)=O Chemical compound CC(C)(C)OC(NCc(c(I)cnc1N(C)C(O)O2)c1C2=O)=O UTFRNYFMGIEIJU-UHFFFAOYSA-N 0.000 description 1
- FRXBDDGVRJAQLZ-UHFFFAOYSA-N CC(C)(C)OC(NCc(c(I)cnc1NC(O2)=O)c1C2=O)=O Chemical compound CC(C)(C)OC(NCc(c(I)cnc1NC(O2)=O)c1C2=O)=O FRXBDDGVRJAQLZ-UHFFFAOYSA-N 0.000 description 1
- CDTVSDFSBOLBGN-UHFFFAOYSA-N CC(C)(C)OC(c1c(CNC(OC(C)(C)C)=O)c(I)cnc1NC)=O Chemical compound CC(C)(C)OC(c1c(CNC(OC(C)(C)C)=O)c(I)cnc1NC)=O CDTVSDFSBOLBGN-UHFFFAOYSA-N 0.000 description 1
- 0 CCNC(C1C(NC)=NC=C(*)C1(C)C**)=O Chemical compound CCNC(C1C(NC)=NC=C(*)C1(C)C**)=O 0.000 description 1
- LKMDGQWQNHBQOU-UHFFFAOYSA-N CN(c(c(C(O1)=O)c2COC(COc(cc3)ccc3F)=O)ncc2I)C1=O Chemical compound CN(c(c(C(O1)=O)c2COC(COc(cc3)ccc3F)=O)ncc2I)C1=O LKMDGQWQNHBQOU-UHFFFAOYSA-N 0.000 description 1
- VOGPZQVCTHTQIF-UHFFFAOYSA-N CN(c(c(C(O1)=O)c2COC(COc3ccccc3)=O)ncc2I)C1=O Chemical compound CN(c(c(C(O1)=O)c2COC(COc3ccccc3)=O)ncc2I)C1=O VOGPZQVCTHTQIF-UHFFFAOYSA-N 0.000 description 1
- SMWAWMYEPAFAMS-UHFFFAOYSA-N OC(c1c2c(Cl)ncc1)OC2=O Chemical compound OC(c1c2c(Cl)ncc1)OC2=O SMWAWMYEPAFAMS-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1241—Nucleotidyltransferases (2.7.7)
- C12N9/1252—DNA-directed DNA polymerase (2.7.7.7), i.e. DNA replicase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6848—Nucleic acid amplification reactions characterised by the means for preventing contamination or increasing the specificity or sensitivity of an amplification reaction
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- Enzymes And Modification Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Priority Applications (8)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR1656791A FR3053968A1 (fr) | 2016-07-13 | 2016-07-13 | Reactifs pour la protection reversible de molecules biologiques |
| US16/314,824 US11708375B2 (en) | 2016-07-13 | 2017-07-13 | Reagents for reversibly protecting biological molecules |
| CN201780043621.XA CN109831913B (zh) | 2016-07-13 | 2017-07-13 | 用于可逆地保护生物分子的试剂 |
| JP2019523188A JP7231540B2 (ja) | 2016-07-13 | 2017-07-13 | 生体分子の可逆的保護のための試薬 |
| PCT/FR2017/051925 WO2018011527A1 (fr) | 2016-07-13 | 2017-07-13 | Réactifs pour la protection réversible de molécules biologiques |
| ES17748542T ES2878581T3 (es) | 2016-07-13 | 2017-07-13 | Reactivos para la protección reversible de moléculas biológicas |
| EP17748542.2A EP3484891B1 (fr) | 2016-07-13 | 2017-07-13 | Réactifs pour la protection réversible de molécules biologiques |
| US18/328,417 US20230322804A1 (en) | 2016-07-13 | 2023-06-02 | Reagents for reversibly protecting biological molecules |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR1656791A FR3053968A1 (fr) | 2016-07-13 | 2016-07-13 | Reactifs pour la protection reversible de molecules biologiques |
| FR1656791 | 2016-07-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FR3053968A1 true FR3053968A1 (fr) | 2018-01-19 |
Family
ID=57286588
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR1656791A Withdrawn FR3053968A1 (fr) | 2016-07-13 | 2016-07-13 | Reactifs pour la protection reversible de molecules biologiques |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US11708375B2 (https=) |
| EP (1) | EP3484891B1 (https=) |
| JP (1) | JP7231540B2 (https=) |
| CN (1) | CN109831913B (https=) |
| ES (1) | ES2878581T3 (https=) |
| FR (1) | FR3053968A1 (https=) |
| WO (1) | WO2018011527A1 (https=) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20230322804A1 (en) * | 2016-07-13 | 2023-10-12 | bioMérieux | Reagents for reversibly protecting biological molecules |
| CA3020818C (en) | 2017-10-13 | 2020-10-20 | Smith Optics, Inc. | Goggle with replaceable lens |
| CN116410951A (zh) * | 2021-12-30 | 2023-07-11 | 广州达安基因股份有限公司 | 一种提高化学修饰的Taq酶的活性的方法和经该方法处理的Taq酶 |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0771870A1 (en) * | 1995-08-25 | 1997-05-07 | F. Hoffmann-La Roche Ag | Reversible inactivation of thermostable enzymes by using dicarboxylic acid anhydride and use in amplification methods |
| WO2004052312A2 (en) * | 2002-12-11 | 2004-06-24 | Smithkline Beecham Corporation | Anti-infectives |
| WO2008149168A1 (en) * | 2007-06-07 | 2008-12-11 | Sanofi-Aventis | Triazolo [1, 5-a] quinolines as adenosine a3 receptor ligands |
| WO2014019966A1 (fr) * | 2012-08-02 | 2014-02-06 | bioMérieux | Procedes de fonctionnalisation et reactifs utilises dans de tels procedes utilisant un anhydride aza-isatoïque ou un de ses derives, molecules biologiques ainsi traitees et kits |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1257526A (fr) | 1960-05-23 | 1961-03-31 | Leffman Ltd S | Perfectionnements apportés aux soutien-gorge |
| WO2009151921A1 (en) | 2008-05-27 | 2009-12-17 | Trilink Biotechnologies | Chemically modified nucleoside 5'-triphosphates for thermally initiated amplification of nucleic acid |
| US8800174B2 (en) | 2010-07-13 | 2014-08-12 | Mission Product Holdings, Inc. | Shoe soles for enhancing gripping with a smooth hard surface |
| WO2012094343A1 (en) | 2011-01-05 | 2012-07-12 | Trilink Biotechnologies | Chemically substituted thermosensitive probes and cofactors for hot start ligation |
| WO2016003929A1 (en) | 2014-07-01 | 2016-01-07 | Rempex Pharmaceuticals, Inc. | Boronic acid derivatives and therapeutic uses thereof |
-
2016
- 2016-07-13 FR FR1656791A patent/FR3053968A1/fr not_active Withdrawn
-
2017
- 2017-07-13 ES ES17748542T patent/ES2878581T3/es active Active
- 2017-07-13 CN CN201780043621.XA patent/CN109831913B/zh active Active
- 2017-07-13 WO PCT/FR2017/051925 patent/WO2018011527A1/fr not_active Ceased
- 2017-07-13 JP JP2019523188A patent/JP7231540B2/ja active Active
- 2017-07-13 EP EP17748542.2A patent/EP3484891B1/fr active Active
- 2017-07-13 US US16/314,824 patent/US11708375B2/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0771870A1 (en) * | 1995-08-25 | 1997-05-07 | F. Hoffmann-La Roche Ag | Reversible inactivation of thermostable enzymes by using dicarboxylic acid anhydride and use in amplification methods |
| WO2004052312A2 (en) * | 2002-12-11 | 2004-06-24 | Smithkline Beecham Corporation | Anti-infectives |
| WO2008149168A1 (en) * | 2007-06-07 | 2008-12-11 | Sanofi-Aventis | Triazolo [1, 5-a] quinolines as adenosine a3 receptor ligands |
| WO2014019966A1 (fr) * | 2012-08-02 | 2014-02-06 | bioMérieux | Procedes de fonctionnalisation et reactifs utilises dans de tels procedes utilisant un anhydride aza-isatoïque ou un de ses derives, molecules biologiques ainsi traitees et kits |
Non-Patent Citations (3)
| Title |
|---|
| G. NORCINI ET AL: "Synthesis and pharmacological evaluation of tyramine congeners containing fused heterocyclic rings", EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, vol. 28, 1993, pages 505 - 511, XP023870315, ISSN: 0223-5234, [retrieved on 19930101], DOI: 10.1016/0223-5234(93)90018-A * |
| ISIDOR MORRIS HEILBRON ET AL: "CCXCII.-Chemical reactivity and conjugation. Part II. The reactivity of the 2-methyl group in the 4-quinazolone series", JOURNAL OF THE CHEMICAL SOCIETY, TRANSACTIONS, vol. 127, 1925, pages 2167 - 2175, XP055327693, ISSN: 0368-1645, DOI: 10.1039/CT9252702167 * |
| TATSUO NAGASAKA ET AL: "Stereoselective synthesis of tilivalline", THE JOURNAL OF ORGANIC CHEMISTRY, vol. 63, no. 20, 1998, pages 6797 - 6801, XP002136000, ISSN: 0022-3263, DOI: 10.1021/JO972158G * |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2019522058A (ja) | 2019-08-08 |
| US11708375B2 (en) | 2023-07-25 |
| US20190375763A1 (en) | 2019-12-12 |
| ES2878581T3 (es) | 2021-11-19 |
| EP3484891B1 (fr) | 2021-04-14 |
| CN109831913A (zh) | 2019-05-31 |
| CN109831913B (zh) | 2022-01-21 |
| JP7231540B2 (ja) | 2023-03-01 |
| WO2018011527A1 (fr) | 2018-01-18 |
| WO2018011527A9 (fr) | 2018-05-03 |
| EP3484891A1 (fr) | 2019-05-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PLFP | Fee payment |
Year of fee payment: 2 |
|
| PLSC | Publication of the preliminary search report |
Effective date: 20180119 |
|
| PLFP | Fee payment |
Year of fee payment: 3 |
|
| PLFP | Fee payment |
Year of fee payment: 4 |
|
| PLFP | Fee payment |
Year of fee payment: 5 |
|
| PLFP | Fee payment |
Year of fee payment: 6 |
|
| ST | Notification of lapse |
Effective date: 20230305 |