ES2878581T3 - Reactivos para la protección reversible de moléculas biológicas - Google Patents

Reactivos para la protección reversible de moléculas biológicas Download PDF

Info

Publication number
ES2878581T3
ES2878581T3 ES17748542T ES17748542T ES2878581T3 ES 2878581 T3 ES2878581 T3 ES 2878581T3 ES 17748542 T ES17748542 T ES 17748542T ES 17748542 T ES17748542 T ES 17748542T ES 2878581 T3 ES2878581 T3 ES 2878581T3
Authority
ES
Spain
Prior art keywords
group
groups
alkyl
biological molecule
heterocycle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES17748542T
Other languages
English (en)
Spanish (es)
Inventor
Sylvain Ursuegui
Alain Laurent
Ali Laayoun
FRéDéRIC FABIS
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biomerieux SA
Universite de Caen Normandie
Original Assignee
Biomerieux SA
Universite de Caen Normandie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomerieux SA, Universite de Caen Normandie filed Critical Biomerieux SA
Application granted granted Critical
Publication of ES2878581T3 publication Critical patent/ES2878581T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6848—Nucleic acid amplification reactions characterised by the means for preventing contamination or increasing the specificity or sensitivity of an amplification reaction
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241—Nucleotidyltransferases (2.7.7)
    • C12N9/1252—DNA-directed DNA polymerase (2.7.7.7), i.e. DNA replicase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ES17748542T 2016-07-13 2017-07-13 Reactivos para la protección reversible de moléculas biológicas Active ES2878581T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR1656791A FR3053968A1 (fr) 2016-07-13 2016-07-13 Reactifs pour la protection reversible de molecules biologiques
PCT/FR2017/051925 WO2018011527A1 (fr) 2016-07-13 2017-07-13 Réactifs pour la protection réversible de molécules biologiques

Publications (1)

Publication Number Publication Date
ES2878581T3 true ES2878581T3 (es) 2021-11-19

Family

ID=57286588

Family Applications (1)

Application Number Title Priority Date Filing Date
ES17748542T Active ES2878581T3 (es) 2016-07-13 2017-07-13 Reactivos para la protección reversible de moléculas biológicas

Country Status (7)

Country Link
US (1) US11708375B2 (https=)
EP (1) EP3484891B1 (https=)
JP (1) JP7231540B2 (https=)
CN (1) CN109831913B (https=)
ES (1) ES2878581T3 (https=)
FR (1) FR3053968A1 (https=)
WO (1) WO2018011527A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20230322804A1 (en) * 2016-07-13 2023-10-12 bioMérieux Reagents for reversibly protecting biological molecules
CA3020818C (en) 2017-10-13 2020-10-20 Smith Optics, Inc. Goggle with replaceable lens
CN116410951A (zh) * 2021-12-30 2023-07-11 广州达安基因股份有限公司 一种提高化学修饰的Taq酶的活性的方法和经该方法处理的Taq酶

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1257526A (fr) 1960-05-23 1961-03-31 Leffman Ltd S Perfectionnements apportés aux soutien-gorge
US5773258A (en) 1995-08-25 1998-06-30 Roche Molecular Systems, Inc. Nucleic acid amplification using a reversibly inactivated thermostable enzyme
AU2003300956A1 (en) * 2002-12-11 2004-06-30 Smithkline Beecham Corporation Anti-infectives
HUP0700395A2 (en) * 2007-06-07 2009-03-02 Sanofi Aventis Substituted [1,2,4] triazolo [1,5-a] quinolines, process for their preparation, pharmaceutical compositions thereof, and intermediates
WO2009151921A1 (en) 2008-05-27 2009-12-17 Trilink Biotechnologies Chemically modified nucleoside 5'-triphosphates for thermally initiated amplification of nucleic acid
US8800174B2 (en) 2010-07-13 2014-08-12 Mission Product Holdings, Inc. Shoe soles for enhancing gripping with a smooth hard surface
WO2012094343A1 (en) 2011-01-05 2012-07-12 Trilink Biotechnologies Chemically substituted thermosensitive probes and cofactors for hot start ligation
FR2994184B1 (fr) * 2012-08-02 2017-12-08 Biomerieux Sa Procedes de fonctionalisation et reactifs utilises dans de tels procedes utilisant un anhydride aza-isatoique ou un de ses derives, molecules biologiques ainsi traitees et kits
WO2016003929A1 (en) 2014-07-01 2016-01-07 Rempex Pharmaceuticals, Inc. Boronic acid derivatives and therapeutic uses thereof

Also Published As

Publication number Publication date
JP2019522058A (ja) 2019-08-08
US11708375B2 (en) 2023-07-25
US20190375763A1 (en) 2019-12-12
EP3484891B1 (fr) 2021-04-14
CN109831913A (zh) 2019-05-31
CN109831913B (zh) 2022-01-21
JP7231540B2 (ja) 2023-03-01
WO2018011527A1 (fr) 2018-01-18
WO2018011527A9 (fr) 2018-05-03
EP3484891A1 (fr) 2019-05-22
FR3053968A1 (fr) 2018-01-19

Similar Documents

Publication Publication Date Title
JP6911248B2 (ja) エンコードライブラリの合成方法及び組成物
Wang et al. Site-specific fluorescent labeling of DNA using Staudinger ligation
ES2878581T3 (es) Reactivos para la protección reversible de moléculas biológicas
EP0885263B1 (en) Benzophenoxazine dyes
JP2009513135A (ja) エンコードされたライブラリーを用いて興味のある化合物を同定する方法
AU2019369192B2 (en) Methods and compositions
Nollet et al. Unconventional nucleotide analogues—I: N9-purinyl α-amino acids
WO2008141799A1 (en) Oligophosphoramidates
Torres-Garcia et al. Side chain anchoring of tryptophan to solid supports using a dihydropyranyl handle: synthesis of brevianamide F
US20230322804A1 (en) Reagents for reversibly protecting biological molecules
Talukder et al. Synthesis of alanyl nucleobase amino acids and their incorporation into proteins
Gondela et al. Versatile synthesis of 2′-amino-2′-deoxyuridine derivatives with a 2′-amino group carrying linkers possessing a reactive terminal functionality
CA2974533A1 (en) Ribosome-mediated incorporation of peptides and peptidomimetics
CA2306958C (en) Process for the synthesis of chloropurine intermediates
CA3008215A1 (en) Substituted naphthalene diimides and their use
CN114129570A (zh) 噁唑烷酮类化合物在制备抗冠状病毒药物中的应用
TW202330571A (zh) 具有光裂解部位的化合物、連結物及使用此的篩選方法
Sunkari et al. 3′-Amino-5′-carboxymethyl-3′, 5′-dideoxy nucleosides for the synthesis of fully amide-linked RNA mimics
WO2020127958A1 (en) Covalent inhibitors of enzyme targets with specific tyrosine-containing motifs
Fukumoto et al. Development of a solid-supported biotinylation reagent for efficient biotin labeling of SH groups on small molecules
Efimov et al. Synthesis of DNA mimics representing HypNA-pPNA hetero-oligomers
Tripathi et al. Polymer supported carbodiimide strategy for the synthesis of N-acylated derivatives of deoxy-and ribo purinenucleosides using active esters
Sheikh et al. First synthesis of non-symmetrical “phthalimidoyl active ester” bi-dentate cross-linking reagents having an acid chloride, 2-benzothiazole, or 1-benzotriazol group
Huang et al. Novel intramolecular aminohydroxylation toward the syntheses of 2′-amino-2′-ethynyl nucleosides
US10421728B2 (en) Peptide nucleic acid monomer and a preparation method