FR2788778A1 - Composition pour la fabrication de capsules a enveloppe dure botaniques, leur procede de fabrication et capsules ainsi obtenues - Google Patents
Composition pour la fabrication de capsules a enveloppe dure botaniques, leur procede de fabrication et capsules ainsi obtenues Download PDFInfo
- Publication number
- FR2788778A1 FR2788778A1 FR9907536A FR9907536A FR2788778A1 FR 2788778 A1 FR2788778 A1 FR 2788778A1 FR 9907536 A FR9907536 A FR 9907536A FR 9907536 A FR9907536 A FR 9907536A FR 2788778 A1 FR2788778 A1 FR 2788778A1
- Authority
- FR
- France
- Prior art keywords
- capsules
- botanical
- tips
- molding
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 238000004519 manufacturing process Methods 0.000 title claims abstract description 19
- 239000000203 mixture Substances 0.000 title claims abstract description 14
- 238000000034 method Methods 0.000 title claims abstract 4
- 239000002775 capsule Substances 0.000 title claims description 52
- 239000007887 hard shell capsule Substances 0.000 claims abstract description 17
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 13
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 8
- 239000001913 cellulose Substances 0.000 claims abstract description 7
- 229920002678 cellulose Polymers 0.000 claims abstract description 7
- 239000008213 purified water Substances 0.000 claims abstract description 7
- 239000003381 stabilizer Substances 0.000 claims abstract description 7
- -1 sucrose fatty acid ester Chemical class 0.000 claims abstract description 7
- 229920002148 Gellan gum Polymers 0.000 claims abstract description 6
- 239000003995 emulsifying agent Substances 0.000 claims abstract description 6
- 239000000216 gellan gum Substances 0.000 claims abstract description 6
- 235000010492 gellan gum Nutrition 0.000 claims abstract description 6
- 235000011187 glycerol Nutrition 0.000 claims abstract description 6
- 239000002994 raw material Substances 0.000 claims abstract description 6
- 229930006000 Sucrose Natural products 0.000 claims abstract description 5
- 235000014113 dietary fatty acids Nutrition 0.000 claims abstract description 5
- 239000000194 fatty acid Substances 0.000 claims abstract description 5
- 229930195729 fatty acid Natural products 0.000 claims abstract description 5
- 239000001509 sodium citrate Substances 0.000 claims abstract description 5
- 239000005720 sucrose Substances 0.000 claims abstract description 5
- 238000001816 cooling Methods 0.000 claims description 28
- 238000000465 moulding Methods 0.000 claims description 24
- 238000007654 immersion Methods 0.000 claims description 10
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims description 8
- 238000001035 drying Methods 0.000 claims description 7
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims description 6
- HRXKRNGNAMMEHJ-UHFFFAOYSA-K trisodium citrate Chemical compound [Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O HRXKRNGNAMMEHJ-UHFFFAOYSA-K 0.000 claims description 2
- 229940038773 trisodium citrate Drugs 0.000 claims description 2
- 230000003028 elevating effect Effects 0.000 claims 1
- 239000004014 plasticizer Substances 0.000 abstract description 6
- 230000007547 defect Effects 0.000 abstract description 3
- 238000010348 incorporation Methods 0.000 abstract description 3
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 abstract description 3
- 239000007903 gelatin capsule Substances 0.000 description 19
- 108010010803 Gelatin Proteins 0.000 description 5
- 229920000159 gelatin Polymers 0.000 description 5
- 239000008273 gelatin Substances 0.000 description 5
- 235000019322 gelatine Nutrition 0.000 description 5
- 235000011852 gelatine desserts Nutrition 0.000 description 5
- 239000007788 liquid Substances 0.000 description 4
- 230000001105 regulatory effect Effects 0.000 description 4
- 238000012360 testing method Methods 0.000 description 3
- 239000003086 colorant Substances 0.000 description 2
- 238000010276 construction Methods 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- 238000003860 storage Methods 0.000 description 2
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 description 1
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 description 1
- 241000656145 Thyrsites atun Species 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 238000005520 cutting process Methods 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000003111 delayed effect Effects 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 150000002148 esters Chemical class 0.000 description 1
- 239000006260 foam Substances 0.000 description 1
- 230000000873 masking effect Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 229940126601 medicinal product Drugs 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 238000013112 stability test Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4816—Wall or shell material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
- A61J3/071—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use into the form of telescopically engaged two-piece capsules
- A61J3/077—Manufacturing capsule shells
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L1/00—Compositions of cellulose, modified cellulose or cellulose derivatives
- C08L1/08—Cellulose derivatives
- C08L1/26—Cellulose ethers
- C08L1/28—Alkyl ethers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Manufacturing & Machinery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Medicinal Preparation (AREA)
- General Preparation And Processing Of Foods (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR19990002204 | 1999-01-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FR2788778A1 true FR2788778A1 (fr) | 2000-07-28 |
Family
ID=19572261
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR9907536A Withdrawn FR2788778A1 (fr) | 1999-01-25 | 1999-06-15 | Composition pour la fabrication de capsules a enveloppe dure botaniques, leur procede de fabrication et capsules ainsi obtenues |
Country Status (5)
| Country | Link |
|---|---|
| JP (1) | JP2000212070A (ja) |
| BE (1) | BE1013079A3 (ja) |
| DE (1) | DE19926714A1 (ja) |
| ES (1) | ES2148114B1 (ja) |
| FR (1) | FR2788778A1 (ja) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2374874A (en) * | 2001-04-11 | 2002-10-30 | Bioprogress Tech Int Inc | Modified cellulose films |
| EP1752140A1 (en) * | 2005-08-12 | 2007-02-14 | Warner-Lambert Company LLC | Method for banding hard capsules using hydroxypropylmethyl cellulose (HPMC) as a base |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006136197A1 (en) | 2005-06-21 | 2006-12-28 | V. Mane Fils | Smoking device incorporating a breakable capsule, breakable capsule and process for manufacturing said capsule |
| WO2006136196A1 (en) * | 2005-06-21 | 2006-12-28 | V. Mane Fils | Gellan seamless breakable capsule and process for manufacturing thereof |
| KR101430018B1 (ko) * | 2005-06-21 | 2014-08-14 | 브이. 만느 피스 | 젤란으로 된 파쇄성 심리스 캡슐 및 그 제조방법 |
| US20080292692A1 (en) * | 2007-05-21 | 2008-11-27 | Shira Pilch | Impermeable Capsules |
| BR112012006651B1 (pt) * | 2009-09-24 | 2021-11-03 | Capsugel Belgium Nv | Cápsula farmacêutica dura resistente a ácido e composição aquosa compreendendo goma de gelano e hpmc |
| KR101136275B1 (ko) | 2009-11-17 | 2012-04-20 | 창성소프트젤 주식회사 | 식물성 젤라틴 캡슐을 제조하기 위한 슬롯다이 |
| CN111433546B (zh) * | 2017-12-06 | 2022-10-25 | 快力胶囊股份有限公司 | 柱状结构物的干燥装置和柱状结构物的制造方法 |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3794453A (en) * | 1972-08-02 | 1974-02-26 | S Padilla | Capsule making apparatus |
| EP0401832A2 (en) * | 1989-06-08 | 1990-12-12 | Shin-Etsu Chemical Co., Ltd. | Method for preparing hard capsules for medicaments |
| US5264223A (en) * | 1990-03-29 | 1993-11-23 | Japan Elanco Company, Ltd. | Hard capsule for pharmaceutical drugs and method for producing the same |
| EP0714656A1 (en) * | 1994-12-01 | 1996-06-05 | Japan Elanco Company Limited | Capsule shell compositions and their use |
| FR2757173A1 (fr) * | 1996-12-17 | 1998-06-19 | Warner Lambert Co | Compositions polymeres d'origine non-animale pour la formation de films |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5431917A (en) * | 1992-10-08 | 1995-07-11 | Japan Elanco Company, Ltd. | Hard capsule for pharmaceutical drugs and method for producing the same |
-
1999
- 1999-06-11 DE DE1999126714 patent/DE19926714A1/de not_active Withdrawn
- 1999-06-11 JP JP11165573A patent/JP2000212070A/ja active Pending
- 1999-06-15 FR FR9907536A patent/FR2788778A1/fr not_active Withdrawn
- 1999-06-15 BE BE9900412A patent/BE1013079A3/fr not_active IP Right Cessation
- 1999-06-15 ES ES9901395A patent/ES2148114B1/es not_active Expired - Fee Related
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3794453A (en) * | 1972-08-02 | 1974-02-26 | S Padilla | Capsule making apparatus |
| EP0401832A2 (en) * | 1989-06-08 | 1990-12-12 | Shin-Etsu Chemical Co., Ltd. | Method for preparing hard capsules for medicaments |
| US5264223A (en) * | 1990-03-29 | 1993-11-23 | Japan Elanco Company, Ltd. | Hard capsule for pharmaceutical drugs and method for producing the same |
| EP0714656A1 (en) * | 1994-12-01 | 1996-06-05 | Japan Elanco Company Limited | Capsule shell compositions and their use |
| FR2757173A1 (fr) * | 1996-12-17 | 1998-06-19 | Warner Lambert Co | Compositions polymeres d'origine non-animale pour la formation de films |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2374874A (en) * | 2001-04-11 | 2002-10-30 | Bioprogress Tech Int Inc | Modified cellulose films |
| EP1752140A1 (en) * | 2005-08-12 | 2007-02-14 | Warner-Lambert Company LLC | Method for banding hard capsules using hydroxypropylmethyl cellulose (HPMC) as a base |
| WO2007020529A3 (en) * | 2005-08-12 | 2007-04-26 | Warner Lambert Co | Method for banding hard capsules using hydroxypropylmethyl cellulose (hpmc) as a base |
| US9579290B2 (en) | 2005-08-12 | 2017-02-28 | Capsugel Belgium Nv | Method for banding hard capsules using hydroxypropylmethyl cellulose (HPMC) as a base |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2000212070A (ja) | 2000-08-02 |
| DE19926714A1 (de) | 2000-08-10 |
| ES2148114B1 (es) | 2001-04-16 |
| BE1013079A3 (fr) | 2001-09-04 |
| ES2148114A1 (es) | 2000-10-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |