FR2622889B1 - Nouveaux derives de demethoxy-4 anthracycline et leur application en therapeutique - Google Patents

Nouveaux derives de demethoxy-4 anthracycline et leur application en therapeutique

Info

Publication number
FR2622889B1
FR2622889B1 FR8814439A FR8814439A FR2622889B1 FR 2622889 B1 FR2622889 B1 FR 2622889B1 FR 8814439 A FR8814439 A FR 8814439A FR 8814439 A FR8814439 A FR 8814439A FR 2622889 B1 FR2622889 B1 FR 2622889B1
Authority
FR
France
Prior art keywords
demethoxy
new
therapeutic application
anthracycline derivatives
anthracycline
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR8814439A
Other languages
English (en)
Other versions
FR2622889A1 (fr
Inventor
Bargiotti Alberto
Grandi Maria
Suarato Antonino
Giuliani Fernando
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmitalia Carlo Erba SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmitalia Carlo Erba SRL filed Critical Farmitalia Carlo Erba SRL
Publication of FR2622889A1 publication Critical patent/FR2622889A1/fr
Application granted granted Critical
Publication of FR2622889B1 publication Critical patent/FR2622889B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
FR8814439A 1987-11-10 1988-11-04 Nouveaux derives de demethoxy-4 anthracycline et leur application en therapeutique Expired - Fee Related FR2622889B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8726272A GB2212154B (en) 1987-11-10 1987-11-10 New 4-demethoxy anthracycline derivatives

Publications (2)

Publication Number Publication Date
FR2622889A1 FR2622889A1 (fr) 1989-05-12
FR2622889B1 true FR2622889B1 (fr) 1994-05-06

Family

ID=10626704

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8814439A Expired - Fee Related FR2622889B1 (fr) 1987-11-10 1988-11-04 Nouveaux derives de demethoxy-4 anthracycline et leur application en therapeutique

Country Status (20)

Country Link
US (1) US5045534A (fr)
JP (1) JPH01153694A (fr)
KR (1) KR890008159A (fr)
AU (1) AU2475088A (fr)
BE (1) BE1001688A5 (fr)
CA (1) CA1312598C (fr)
DE (1) DE3837755A1 (fr)
DK (2) DK624688D0 (fr)
ES (1) ES2012564A6 (fr)
FI (1) FI885063A (fr)
FR (1) FR2622889B1 (fr)
GB (1) GB2212154B (fr)
GR (1) GR880100755A (fr)
HU (1) HU199862B (fr)
IL (1) IL88311A0 (fr)
IT (1) IT1228882B (fr)
NL (1) NL8802721A (fr)
PT (1) PT88961B (fr)
SE (1) SE8804037L (fr)
ZA (1) ZA888368B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8818167D0 (en) * 1988-07-29 1988-09-01 Erba Carlo Spa Novel 4-substituted anthracyclinones & process for their preparation
GB9019934D0 (en) * 1990-09-12 1990-10-24 Erba Carlo Spa 2-hydroxy-and 2-acyloxy-4-morpholinyl anthracyclines
GB9028105D0 (en) * 1990-12-27 1991-02-13 Erba Carlo Spa Process for the preparation of substituted benzofuran derivatives
GB9216962D0 (en) * 1992-08-11 1992-09-23 Erba Carlo Spa Therapeutically active naphthalenesulfonic-pyrrolecarboxamido derivatives

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1467383A (en) * 1974-06-12 1977-03-16 Farmaceutici Italia Daunomycin analogues
GB1511559A (en) * 1975-09-26 1978-05-24 Farmaceutici Italia Anthracycline glycosides
GB1511680A (en) * 1975-11-18 1978-05-24 Farmaceutici Italia Daunosaminyl anthracyclinones
DE51280T1 (de) * 1980-11-01 1983-01-20 Farmitalia Carlo Erba S.p.A., 20159 Milano Anthracyclin-glycoside, verfahren zu ihrer herstellung, zwischenprodukte und ihre herstellung und arzneimittel.
FI75834C (fi) * 1982-05-24 1988-08-08 Erba Farmitalia Foerfarande foer framstaellning av antracyklinglykosidfoereningar.
US4448724A (en) * 1982-12-20 1984-05-15 The Trustees Of The University Of Pennsylvania Synthesis of 4-demethoxydaunomycinone
JPS60115598A (ja) * 1983-11-26 1985-06-22 Sumitomo Chem Co Ltd アンスラサイクリン誘導体
JPS617289A (ja) * 1984-06-22 1986-01-13 Sagami Chem Res Center ３′−ｎ−トリフルオロアセチル−４−デメトキシアドリアマイシン
JPS6150992A (ja) * 1984-08-21 1986-03-13 Sumitomo Chem Co Ltd アンスラサイクリン誘導体とその製法
JPS6178797A (ja) * 1984-09-25 1986-04-22 Sagami Chem Res Center ４−デメトキシアドリアマイシン

Also Published As

Publication number Publication date
FR2622889A1 (fr) 1989-05-12
SE8804037L (sv) 1989-05-11
FI885063A0 (fi) 1988-11-03
DK624688D0 (da) 1988-11-09
IL88311A0 (en) 1989-06-30
JPH01153694A (ja) 1989-06-15
FI885063A (fi) 1989-05-11
NL8802721A (nl) 1989-06-01
AU2475088A (en) 1989-06-29
BE1001688A5 (fr) 1990-02-06
DK624588D0 (da) 1988-11-09
GB2212154A (en) 1989-07-19
GR880100755A (el) 1994-03-31
PT88961B (pt) 1994-08-31
ZA888368B (en) 1989-09-27
CA1312598C (fr) 1993-01-12
SE8804037D0 (sv) 1988-11-08
DE3837755A1 (de) 1989-05-18
HUT48639A (en) 1989-06-28
GB8726272D0 (en) 1987-12-16
ES2012564A6 (es) 1990-04-01
KR890008159A (ko) 1989-07-10
IT1228882B (it) 1991-07-09
PT88961A (pt) 1989-11-30
GB2212154B (en) 1991-03-27
DK624588A (da) 1989-05-11
IT8822539A0 (it) 1988-11-07
US5045534A (en) 1991-09-03
HU199862B (en) 1990-03-28

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Legal Events

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ST Notification of lapse