FR2584072B1 - Nouveaux derives d'isoquinoleine, leur procede de preparation, leur application en therapeutique et produits intermediaires - Google Patents

Nouveaux derives d'isoquinoleine, leur procede de preparation, leur application en therapeutique et produits intermediaires

Info

Publication number
FR2584072B1
FR2584072B1 FR868607726A FR8607726A FR2584072B1 FR 2584072 B1 FR2584072 B1 FR 2584072B1 FR 868607726 A FR868607726 A FR 868607726A FR 8607726 A FR8607726 A FR 8607726A FR 2584072 B1 FR2584072 B1 FR 2584072B1
Authority
FR
France
Prior art keywords
novel
preparation process
intermediate products
therapeutic application
isoquinolein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR868607726A
Other languages
English (en)
Other versions
FR2584072A1 (fr
Inventor
Gordon Hanley Phillipps
Esme Joan Bailey
Michael George Lester
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of FR2584072A1 publication Critical patent/FR2584072A1/fr
Application granted granted Critical
Publication of FR2584072B1 publication Critical patent/FR2584072B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
FR868607726A 1985-05-29 1986-05-29 Nouveaux derives d'isoquinoleine, leur procede de preparation, leur application en therapeutique et produits intermediaires Expired - Fee Related FR2584072B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB858513460A GB8513460D0 (en) 1985-05-29 1985-05-29 Chemical compounds

Publications (2)

Publication Number Publication Date
FR2584072A1 FR2584072A1 (fr) 1987-01-02
FR2584072B1 true FR2584072B1 (fr) 1991-04-19

Family

ID=10579796

Family Applications (1)

Application Number Title Priority Date Filing Date
FR868607726A Expired - Fee Related FR2584072B1 (fr) 1985-05-29 1986-05-29 Nouveaux derives d'isoquinoleine, leur procede de preparation, leur application en therapeutique et produits intermediaires

Country Status (18)

Country Link
US (1) US4900737A (fr)
JP (1) JPS6212778A (fr)
KR (1) KR860009015A (fr)
BE (1) BE904835A (fr)
CH (2) CH668596A5 (fr)
DE (1) DE3617938A1 (fr)
DK (1) DK246986A (fr)
ES (2) ES8800942A1 (fr)
FI (1) FI862277A (fr)
FR (1) FR2584072B1 (fr)
GB (2) GB8513460D0 (fr)
IT (1) IT1191931B (fr)
NL (1) NL8601381A (fr)
NO (1) NO862120L (fr)
NZ (1) NZ216338A (fr)
PH (2) PH24002A (fr)
SE (2) SE8602434L (fr)
ZA (1) ZA864015B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK616087A (da) * 1986-11-27 1988-05-28 Glaxo Group Ltd Isoquinolinderivater og farmaceutiske praeparater indeholdende dem
GB8800312D0 (en) * 1988-01-07 1988-02-10 Glaxo Group Ltd Process
FR2801309B1 (fr) * 1999-11-18 2002-01-04 Adir Nouveaux composes analogues de la camptothecine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
CN114805204B (zh) * 2022-04-01 2023-09-15 云南师范大学 一种制备4-碘异喹啉-1(2h)-酮类化合物的方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4029659A (en) * 1971-03-29 1977-06-14 Omnium Chimique Societe Anonyme N-disubstituted aminoethyl esters of 11-methoxy-raubasinic acid
US3894029A (en) * 1971-08-26 1975-07-08 Basf Ag Production of camptothecin and camptothecin-like compounds
US3903276A (en) * 1972-03-20 1975-09-02 American Home Prod N-carboxymethyl-N-substituted glycinate esters of 3-hydroxy-1,4-benzodiazepin-2-ones for inducing a calming effect
US4301285A (en) * 1980-10-02 1981-11-17 American Home Products Corporation Sydnonimine CNS stimulants
NL8202626A (nl) * 1982-06-29 1984-01-16 Stichting Rega V Z W Derivaten van 9-(2-hydroxyethoxymethyl)guanine.
DK158666C (da) * 1982-11-04 1990-11-19 Glaxo Group Ltd Analogifremgangsmaade til fremstilling af 5,14-dihydrobenz-oe5,6aa-isoindolooe2,1-baa-isoquinolin-8,13-dion
NZ211960A (en) * 1984-05-03 1989-05-29 Glaxo Group Ltd Benz(5,6)isoindolo(2,1-b)isoquinoline-8,13-dione derivatives and pharmaceutical compositions

Also Published As

Publication number Publication date
ES557703A0 (es) 1988-01-01
BE904835A (fr) 1986-11-28
DK246986A (da) 1986-11-30
PH24375A (en) 1990-06-13
FR2584072A1 (fr) 1987-01-02
CH668596A5 (de) 1989-01-13
ES555407A0 (es) 1987-12-01
GB8513460D0 (en) 1985-07-03
ZA864015B (en) 1988-01-27
DE3617938A1 (de) 1986-12-04
ES8800942A1 (es) 1987-12-01
SE464523B (sv) 1991-05-06
CH671959A5 (fr) 1989-10-13
SE8602434L (sv) 1986-11-30
IT8648070A0 (it) 1986-05-28
GB2175587B (en) 1989-10-11
DK246986D0 (da) 1986-05-27
PH24002A (en) 1990-02-09
US4900737A (en) 1990-02-13
JPS6212778A (ja) 1987-01-21
IT1191931B (it) 1988-03-31
KR860009015A (ko) 1986-12-19
FI862277A0 (fi) 1986-05-29
GB8612950D0 (en) 1986-07-02
NO862120L (no) 1986-12-01
ES8801212A1 (es) 1988-01-01
SE8904107D0 (sv) 1989-12-05
SE8602434D0 (sv) 1986-05-28
NZ216338A (en) 1989-03-29
AU591905B2 (en) 1989-12-21
GB2175587A (en) 1986-12-03
FI862277A (fi) 1986-11-30
NL8601381A (nl) 1986-12-16
AU5807386A (en) 1986-12-04

Similar Documents

Publication Publication Date Title
BE892270A (fr) Nouveaux derives aminomethyl-5 oxazolidiniques, leur procede de preparation et leur application en therapeutique
FR2493848B2 (fr) Nouveaux derives des nor-tropane et granatane, leur procede de preparation et leur application en therapeutique
BE892758A (fr) Derives phenylcyclobutyliques, leur procede de preparation et leur application therapeutique
FR2504920B1 (fr) Derives phenylcyclobutyliques, leur procede de preparation et leur application therapeutique
FR2586683B1 (fr) Nouveaux derives de neothramycine, leur procede de preparation et leur application en tant que medicaments
FR2629715B1 (fr) Derives de l'adenosine, leur procede de preparation et leur utilisation en therapeutique
FR2738571B1 (fr) Nouveaux derives de la 5-0-desosaminyl 6-0-methyl- erythronolide a, leur procede de preparation et leur application a la preparation de produits biologiquement actifs
FR2634122B1 (fr) Derives de furanne et leur procede de preparation
FR2506306B1 (fr) Nouveaux derives de l'amidinopiperidine, leur procede de preparation et leur application en therapeutique
FR2621588B1 (fr) Nouveaux derives de la 1,1-dioxo 1,2-benzoisothiazol 3-one, leur procede de preparation et leur application comme medicaments
FR2560195B1 (fr) Derives d'alanyl-proline, leur procede de preparation et leurs applications pharmaceutiques
FR2605004B1 (fr) Nouveaux derives d'amino-acides, leur procede de preparation et composition pharmaceutiques les contenant
FR2510583B1 (fr) Derives nouveaux d'acide ursodesoxycholique, leur procede de preparation et leur application en therapeutique
FR2590897B1 (fr) Nouveaux derives de 6 amino 1,2-dihydro-1-hydroxy-2-imino-pyrimidine, leur procede de preparation et compositions cosmetiques les renfermant
FR2556721B1 (fr) Nouveaux derives de o-mercaptopropanamide d'o amino-acides, leur procede de preparation, leur application comme medicaments et les compositions les renfermant
BE884620A (fr) Nouveaux derives d'halovincamone, leur procede de preparation et medicaments les contenant
FR2520739B1 (fr) Nouveaux derives d'ester indoleacetique, leur procede de preparation et leur application en therapeutique
FR2582835B1 (fr) Derives de la quinoleine, leur procede de preparation et compositions pharmaceutiques les contenant
FR2584072B1 (fr) Nouveaux derives d'isoquinoleine, leur procede de preparation, leur application en therapeutique et produits intermediaires
FR2596759B1 (fr) Nouveaux derives du chromane et du thiochromane, leur procede de preparation et compositions medicamenteuse et cosmetique les contenant
FR2592042B1 (fr) Nouveaux ortho-anisamides, leur procede d'obtention, et leurs applications therapeutiques
FR2594439B1 (fr) Nouveaux derives ester, thioester et amide de quinolone, leur procede de preparation et leur application en therapeutique
FR2477142B1 (fr) Nouveaux derives de la nitrosouree, leur procede de preparation et leur application en therapeutique
PT80914A (fr) Methode de preparation des nouveaux derives d'(arylpiperaziniletilaminoetoxi)-4-fenol et leur application therapeutique
FR2572075B1 (fr) Nouveaux derives de la 4-dioxino-(4,5-c)-pyridine et leur procede de preparation

Legal Events

Date Code Title Description
ST Notification of lapse