FR2568570B1 - Procede pour la fabrication de derives 3-substitues du 1-amino-2-hydroxypropane - Google Patents

Procede pour la fabrication de derives 3-substitues du 1-amino-2-hydroxypropane

Info

Publication number
FR2568570B1
FR2568570B1 FR858511799A FR8511799A FR2568570B1 FR 2568570 B1 FR2568570 B1 FR 2568570B1 FR 858511799 A FR858511799 A FR 858511799A FR 8511799 A FR8511799 A FR 8511799A FR 2568570 B1 FR2568570 B1 FR 2568570B1
Authority
FR
France
Prior art keywords
hydroxypropane
amino
manufacture
substituted derivatives
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR858511799A
Other languages
English (en)
Other versions
FR2568570A1 (fr
Inventor
Piero Melloni
Arturo Della Torre
Ettore Lazzari
Giuseppe Mazzini
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Italia SRL
Original Assignee
Farmitalia Carlo Erba SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmitalia Carlo Erba SRL filed Critical Farmitalia Carlo Erba SRL
Publication of FR2568570A1 publication Critical patent/FR2568570A1/fr
Application granted granted Critical
Publication of FR2568570B1 publication Critical patent/FR2568570B1/fr
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/12Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/24Ethers with hydroxy compounds containing no oxirane rings with polyhydroxy compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00Sulfonic acids; Halides, esters, or anhydrides thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00Ethers; Compounds having groups, groups or groups
    • C07C43/02Ethers
    • C07C43/20Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/12Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/14Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by free hydroxyl radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR858511799A 1984-08-02 1985-08-01 Procede pour la fabrication de derives 3-substitues du 1-amino-2-hydroxypropane Expired FR2568570B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB848419683A GB8419683D0 (en) 1984-08-02 1984-08-02 3-substituted derivatives of 1-amino-2-hydroxy-propane

Publications (2)

Publication Number Publication Date
FR2568570A1 FR2568570A1 (fr) 1986-02-07
FR2568570B1 true FR2568570B1 (fr) 1989-05-19

Family

ID=10564819

Family Applications (1)

Application Number Title Priority Date Filing Date
FR858511799A Expired FR2568570B1 (fr) 1984-08-02 1985-08-01 Procede pour la fabrication de derives 3-substitues du 1-amino-2-hydroxypropane

Country Status (9)

Country Link
US (2) US5068433A (fr)
JP (1) JPH0657682B2 (fr)
CA (1) CA1340854C (fr)
CH (1) CH666261A5 (fr)
DE (1) DE3527241C2 (fr)
FI (1) FI84909C (fr)
FR (1) FR2568570B1 (fr)
GB (1) GB8419683D0 (fr)
IT (1) IT1187717B (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6005102A (en) 1997-10-15 1999-12-21 American Home Products Corporation Aryloxy-alkyl-dialkylamines
JP2002511414A (ja) 1998-04-09 2002-04-16 ファルマシア・アンド・アップジョン・カンパニー 神経疾患のための新しい治療
US6586427B2 (en) * 1998-04-09 2003-07-01 Pharmacia & Upjohn Company Treatments for nervous disorders
IT1305322B1 (it) 1998-04-23 2001-05-04 Pharmacia & Upjohn Spa Uso di reboxetina per il trattamento di disturbi nervosi
CN1249038C (zh) 1998-12-29 2006-04-05 法玛西雅厄普约翰美国公司 芳基醚的制备方法
PT1459750E (pt) * 1999-07-01 2005-08-31 Pharmacia & Upjohn Co Llc (s,s)- reboxetina para tratar a fibromialgia ou outras perturbacoes somatoformes
EP1530476A1 (fr) * 2002-08-14 2005-05-18 Pharmacia & Upjohn Company LLC Utilisation de reboxetine dans le traitement de bouffees de chaleur
EP1675582A1 (fr) * 2003-09-12 2006-07-05 Warner-Lambert Company LLC Combinaison comportant un ligand alpha-2-delta et un inhibiteur selectif du recaptage de la serotonine et/ou un inhibiteur selectif du recaptage de la noradrenaline et permettant le traitement de la depression et des troubles anxieux
CA2537402C (fr) 2003-09-12 2009-05-05 Pfizer Inc. Associations comprenant des ligands alpha-2-delta et des inhibiteurs du recaptage de la serotonine et de la noradrenaline
EP1730094A1 (fr) * 2004-02-20 2006-12-13 Pharmacia & Upjohn Company LLC Procede pour la preparation d'ethers aryle
WO2005082869A1 (fr) * 2004-02-20 2005-09-09 Pharmacia & Upjohn Company Llc Procede pour la preparation d'ethers aryle
JP4185154B2 (ja) * 2004-04-30 2008-11-26 ワーナー−ランバート カンパニー リミテッド ライアビリティー カンパニー 中枢神経系障害治療用の置換モルホリン化合物
GB0409744D0 (en) * 2004-04-30 2004-06-09 Pfizer Ltd Novel compounds
DE602007010909D1 (de) * 2006-03-10 2011-01-13 Tokyo Inst Tech Verfahren zur herstellung eines flavanderivats
WO2008019431A1 (fr) * 2006-08-14 2008-02-21 Brc Operations Pty Limited Procédé et compositions pour réguler simultanément la mémoire et l'humeur
WO2008122019A1 (fr) * 2007-04-02 2008-10-09 Cypress Biosciences, Inc. Amélioration de la tolérabilité de la mirtazapine et de la réboxétine par leur utilisation en combinaison
US20100069389A1 (en) * 2008-09-06 2010-03-18 Bionevia Pharmaceuticals, Inc. Novel forms of reboxetine
CN102101831A (zh) * 2009-12-17 2011-06-22 天津药物研究院 制备(2rs,3sr)-3-(2-乙氧基苯氧基)-2-羟基-1-(4-硝基苯甲酰氧基)-3-苯基丙烷的方法
CN104086431A (zh) * 2014-07-21 2014-10-08 天津药物研究院药业有限责任公司 一种甲磺酸瑞波西汀中间体的合成方法
CN104557936A (zh) * 2015-01-15 2015-04-29 河南科技学院 一种新型手性非环嘌呤核苷类似物的合成方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2977374A (en) * 1961-03-28 Process for preparing oxirane
US2252039A (en) * 1936-06-30 1941-08-12 Heberlein Patent Corp Process of rendering textiles water repellent
GB1128052A (en) * 1965-06-08 1968-09-25 Ici Ltd Alkanolamine derivatives
GB1387630A (en) * 1971-05-07 1975-03-19 Ici Ltd Phenoxyalkanolamine derivatives
GB1458392A (en) * 1973-11-09 1976-12-15 Ici Ltd Optically-active 1-aryloxy-2,3-epoxypropane derivatives
US3987086A (en) * 1974-12-12 1976-10-19 Ciba-Geigy Corporation Hindered hydroxyphenylalkanoates of substituted vicinal glycols
AT341274B (de) * 1976-01-09 1978-01-25 Hoffmann La Roche Mittel zur regulation des insektenwachstums
DE2645710C2 (de) * 1976-10-09 1985-06-27 Merck Patent Gmbh, 6100 Darmstadt Phenoxy-amino-propanole, Verfahren zu ihrer Herstellung und pharmazeutische Zubereitung
US4263325A (en) * 1977-10-05 1981-04-21 Aktiebolaget Hassle β-Receptor blocking compounds and treatment of cardiovascular disorders therewith
IL56369A (en) * 1978-01-20 1984-05-31 Erba Farmitalia Alpha-phenoxybenzyl propanolamine derivatives,their preparation and pharmaceutical compositions comprising them
US4341718A (en) * 1978-07-03 1982-07-27 American Home Products Corporation α-[(Alkylamino)-methyl]-β-aryloxy-benzeneethanols exhibiting antiarrhythmic activity
US4777291A (en) * 1985-02-27 1988-10-11 Eli Lilly And Company Racemization process

Also Published As

Publication number Publication date
CH666261A5 (de) 1988-07-15
IT1187717B (it) 1987-12-23
FI84909B (fi) 1991-10-31
US5068433A (en) 1991-11-26
FI852964A0 (fi) 1985-07-31
FI84909C (fi) 1992-02-10
FI852964L (fi) 1986-02-03
JPS6147448A (ja) 1986-03-07
CA1340854C (fr) 1999-12-21
IT8521763A0 (it) 1985-07-30
DE3527241A1 (de) 1986-02-13
FR2568570A1 (fr) 1986-02-07
US5391735A (en) 1995-02-21
JPH0657682B2 (ja) 1994-08-03
GB8419683D0 (en) 1984-09-05
DE3527241C2 (de) 1995-12-14

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Legal Events

Date Code Title Description
TP Transmission of property
CD Change of name or company name
TP Transmission of property
CA Change of address
CD Change of name or company name
TP Transmission of property