FR2558262B1 - Procede et systeme pour l'analyse par electrophorese de fragments d'adn obtenus par sequencage - Google Patents

Procede et systeme pour l'analyse par electrophorese de fragments d'adn obtenus par sequencage

Info

Publication number
FR2558262B1
FR2558262B1 FR8500597A FR8500597A FR2558262B1 FR 2558262 B1 FR2558262 B1 FR 2558262B1 FR 8500597 A FR8500597 A FR 8500597A FR 8500597 A FR8500597 A FR 8500597A FR 2558262 B1 FR2558262 B1 FR 2558262B1
Authority
FR
France
Prior art keywords
sequencing
dna fragments
fragments obtained
electrophoresis analysis
electrophoresis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8500597A
Other languages
English (en)
French (fr)
Other versions
FR2558262A1 (fr
Inventor
Leroy E Hood
Michael W Hunkapiller
Lloyd M Smith
Tim J Hunkapiller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
California Institute of Technology CalTech
Original Assignee
California Institute of Technology CalTech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by California Institute of Technology CalTech filed Critical California Institute of Technology CalTech
Publication of FR2558262A1 publication Critical patent/FR2558262A1/fr
Application granted granted Critical
Publication of FR2558262B1 publication Critical patent/FR2558262B1/fr
Expired legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44704—Details; Accessories
    • G01N27/44717—Arrangements for investigating the separated zones, e.g. localising zones
    • G01N27/44721—Arrangements for investigating the separated zones, e.g. localising zones by optical means
    • G01N27/44726—Arrangements for investigating the separated zones, e.g. localising zones by optical means using specific dyes, markers or binding molecules
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44704—Details; Accessories
    • G01N27/44717—Arrangements for investigating the separated zones, e.g. localising zones
    • G01N27/44721—Arrangements for investigating the separated zones, e.g. localising zones by optical means

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Pathology (AREA)
  • Electrochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
FR8500597A 1984-01-16 1985-01-16 Procede et systeme pour l'analyse par electrophorese de fragments d'adn obtenus par sequencage Expired FR2558262B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US57097384A 1984-01-16 1984-01-16
US68901385A 1985-01-02 1985-01-02

Publications (2)

Publication Number Publication Date
FR2558262A1 FR2558262A1 (fr) 1985-07-19
FR2558262B1 true FR2558262B1 (fr) 1989-04-07

Family

ID=27075453

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8500597A Expired FR2558262B1 (fr) 1984-01-16 1985-01-16 Procede et systeme pour l'analyse par electrophorese de fragments d'adn obtenus par sequencage

Country Status (5)

Country Link
CA (1) CA1258611A (sv)
DE (1) DE3501306C2 (sv)
FR (1) FR2558262B1 (sv)
GB (1) GB2155176B (sv)
SE (1) SE456348B (sv)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4865968A (en) * 1985-04-01 1989-09-12 The Salk Institute For Biological Studies DNA sequencing
US4855225A (en) * 1986-02-07 1989-08-08 Applied Biosystems, Inc. Method of detecting electrophoretically separated oligonucleotides
US4811218A (en) * 1986-06-02 1989-03-07 Applied Biosystems, Inc. Real time scanning electrophoresis apparatus for DNA sequencing
DE3618605A1 (de) * 1986-06-03 1987-12-10 Europ Lab Molekularbiolog Vorrichtung zur detektion von zur photonenemission anregbaren stoffen
DE3621631A1 (de) * 1986-06-27 1988-01-14 Hirschmann Geraetebau Gmbh & C Geraet zur abbildung eines objektes auf einem elektrooptischen wandler
US5242796A (en) * 1986-07-02 1993-09-07 E. I. Du Pont De Nemours And Company Method, system and reagents for DNA sequencing
CA1340806C (en) * 1986-07-02 1999-11-02 James Merrill Prober Method, system and reagents for dna sequencing
JPH0799353B2 (ja) * 1987-03-31 1995-10-25 株式会社島津製作所 塩基配列決定装置
EP0294524B1 (en) * 1987-06-09 1997-11-26 The Perkin-Elmer Corporation Real time scanning electrophoresis apparatus for DNA sequencing
US4833332A (en) * 1987-06-12 1989-05-23 E. I. Du Pont De Nemours And Company Scanning fluorescent detection system
US5102785A (en) * 1987-09-28 1992-04-07 E. I. Du Pont De Nemours And Company Method of gene mapping
JPH01224657A (ja) * 1988-03-04 1989-09-07 Hitachi Ltd 核酸の塩基配列決定装置
EP0341928A1 (en) * 1988-05-10 1989-11-15 AMERSHAM INTERNATIONAL plc Improvements relating to surface plasmon resonance sensors
SE8802573D0 (sv) * 1988-07-08 1988-07-08 Wallac Oy Multi-label time-resolved fluorescence analysis of nucleic acid sequences using lanthanide chelates
FR2636738B1 (fr) * 1988-09-20 1992-12-11 Commissariat Energie Atomique Procede et installation de sequencage de l'adn
FR2636739B1 (fr) * 1988-09-20 1993-02-12 Commissariat Energie Atomique Procede et installation d'identification des bases d'un adn
US5061361A (en) * 1989-03-06 1991-10-29 Hewlett-Packard Company Capillary zone electrophoresis cell system
FR2649487B1 (fr) * 1989-06-21 1991-09-20 Europhor Sa Capillaire d'electrophorese a dispositif optique incorpore
US5274240A (en) * 1990-01-12 1993-12-28 The Regents Of The University Of California Capillary array confocal fluorescence scanner and method
FR2671407B1 (fr) * 1991-01-08 1994-08-05 Europhor Sa Procede d'analyse par electrophorese capillaire avec detection par fluorescence, et dispositifs de mise en óoeuvre.
US5203339A (en) * 1991-06-28 1993-04-20 The Government Of The United States Of America As Represented By The Secretary Of The Department Health And Human Services Method and apparatus for imaging a physical parameter in turbid media using diffuse waves
US5273638A (en) * 1991-09-30 1993-12-28 Beckman Instruments, Inc. Nucleotide sequence determination employing matched dideoxynucleotide terminator concentrations
EP0539743B1 (en) * 1991-09-30 1997-08-06 Beckman Instruments, Inc. Enhanced fluorescence detection of samples in capillary column
US5484571A (en) * 1991-10-08 1996-01-16 Beckman Instruments, Inc. Enhanced fluorescence detection of samples in capillary column
AU3816993A (en) * 1992-03-19 1993-10-21 Regents Of The University Of California, The Multiple tag labeling method for DNA sequencing
JPH05332992A (ja) * 1992-05-29 1993-12-17 Shimadzu Corp 電気泳動装置
DE4336911C2 (de) * 1993-10-28 2002-11-21 Biotechnolog Forschung Gmbh Verfahren zur Primer-Herstellung und Template-Bank dafür
JP3068413B2 (ja) * 1994-07-13 2000-07-24 日立電子エンジニアリング株式会社 Ｄｎａ塩基配列決定装置
US5675155A (en) * 1995-04-26 1997-10-07 Beckman Instruments, Inc. Multicapillary fluorescent detection system
US6110683A (en) * 1999-01-08 2000-08-29 Commonwealth Biotechnologies, Inc. Automated DNA Sequencer loading dye which contains a lane tracking aid

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1205028A (en) * 1981-07-01 1986-05-27 Jerald C. Hinshaw Fluorescent chelates and labeled specific binding reagents prepared therefrom
CA1180647A (en) * 1981-07-17 1985-01-08 Cavit Akin Light-emitting polynucleotide hybridization diagnostic method
FR2519005B1 (fr) * 1981-12-29 1985-10-25 Pasteur Institut Fragments d'adn marques a l'une au moins de leurs extremites par des ribonucleotides modifies reconnaissables par des molecules affines et procede pour realiser une analyse de tels fragments d'adn
DK105582A (da) * 1982-03-11 1983-09-12 Nordisk Insulinlab Fremgangsmaade til bestemmelse af humane hla-d(r) vaevstyper og gensonde til brug ved fremgangsmaaden
US4490472A (en) * 1982-06-17 1984-12-25 Imreg, Inc. Sensitive tests for malignancies based on DNA detection

Also Published As

Publication number Publication date
CA1258611A (en) 1989-08-22
SE456348B (sv) 1988-09-26
DE3501306C2 (de) 1998-09-24
SE8500201L (sv) 1985-07-17
GB8500960D0 (en) 1985-02-20
GB2155176B (en) 1988-05-11
GB2155176A (en) 1985-09-18
DE3501306A1 (de) 1985-07-25
FR2558262A1 (fr) 1985-07-19
SE8500201D0 (sv) 1985-01-16

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Legal Events

Date Code Title Description
ST Notification of lapse
RN Application for restoration
FC Favourable decision of inpi director general on an application for restauration.