FR2547813B1 - 3-(3-hydroxybutoxy)-1-butanol et sa preparation - Google Patents

3-(3-hydroxybutoxy)-1-butanol et sa preparation

Info

Publication number
FR2547813B1
FR2547813B1 FR848408571A FR8408571A FR2547813B1 FR 2547813 B1 FR2547813 B1 FR 2547813B1 FR 848408571 A FR848408571 A FR 848408571A FR 8408571 A FR8408571 A FR 8408571A FR 2547813 B1 FR2547813 B1 FR 2547813B1
Authority
FR
France
Prior art keywords
hydroxybutoxy
butanol
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR848408571A
Other languages
English (en)
French (fr)
Other versions
FR2547813A1 (fr
Inventor
Elso Manghisi
Aldo Salimbeni
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Istituto Luso Farmaco dItalia SpA
Original Assignee
Istituto Luso Farmaco dItalia SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Istituto Luso Farmaco dItalia SpA filed Critical Istituto Luso Farmaco dItalia SpA
Publication of FR2547813A1 publication Critical patent/FR2547813A1/fr
Application granted granted Critical
Publication of FR2547813B1 publication Critical patent/FR2547813B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/04—Saturated ethers
    • C07C43/13—Saturated ethers containing hydroxy or O-metal groups
    • C07C43/132—Saturated ethers containing hydroxy or O-metal groups both carbon chains being substituted by hydroxy or O-metal groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/14—Unsaturated ethers
    • C07C43/164—Unsaturated ethers containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
    • C07C43/14—Unsaturated ethers
    • C07C43/178—Unsaturated ethers containing hydroxy or O-metal groups
    • C07C43/1785—Unsaturated ethers containing hydroxy or O-metal groups having more than one ether bound

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR848408571A 1983-05-30 1984-05-30 3-(3-hydroxybutoxy)-1-butanol et sa preparation Expired FR2547813B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT21352/83A IT1164254B (it) 1983-05-30 1983-05-30 3-(3-idrossibutossi)-1-butanolo e suo metodo di preparazione

Publications (2)

Publication Number Publication Date
FR2547813A1 FR2547813A1 (fr) 1984-12-28
FR2547813B1 true FR2547813B1 (fr) 1989-01-27

Family

ID=11180528

Family Applications (1)

Application Number Title Priority Date Filing Date
FR848408571A Expired FR2547813B1 (fr) 1983-05-30 1984-05-30 3-(3-hydroxybutoxy)-1-butanol et sa preparation

Country Status (8)

Country Link
US (1) US4584321A (cg-RX-API-DMAC10.html)
JP (1) JPS604146A (cg-RX-API-DMAC10.html)
BE (1) BE899790A (cg-RX-API-DMAC10.html)
DE (1) DE3419947A1 (cg-RX-API-DMAC10.html)
ES (1) ES532802A0 (cg-RX-API-DMAC10.html)
FR (1) FR2547813B1 (cg-RX-API-DMAC10.html)
GB (1) GB2142623B (cg-RX-API-DMAC10.html)
IT (1) IT1164254B (cg-RX-API-DMAC10.html)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL145712A0 (en) * 1999-04-01 2002-07-25 Esperion Therapeutics Inc Ether compounds, compositions, and uses thereof
US20040122091A1 (en) * 2000-10-11 2004-06-24 Esperion Therapeutics, Inc. Sulfoxide and bis-sulfoxide compounds and compositions for cholesterol management and related uses
BR0114617A (pt) 2000-10-11 2005-12-13 Esperion Therapeutics Inc Composto, composição farmacêutica, métodos para tratar ou previnir uma doença cardiovascular, uma dislipidemia, uma dislipoproteinemia, um distúrbio do metabolismo da glicose, trombótico e associado com o receptor ativado do proliferador de peroxissoma, a doença de alzheimer, a sìndrome x ou sìndrome metabólica, a septicemia, a obesidade, pancreatite, a hipertensão, doença renal, câncer, a inflamação e a impotência, em um paciente e para reduzir o teor de gordura da carne em animal de criação e de colesterol de ovos de aves domésticas
JP2004531459A (ja) 2000-10-11 2004-10-14 エスペリオン セラピューティクス，インコーポレイテッド コレステロールマネージメント用スルホキシドおよびビススルホキシド化合物ならびに組成物および関連する使用
CA2425311C (en) 2000-10-11 2011-06-14 Esperion Therapeutics, Inc. Ketone compounds and compositions for cholesterol management and related uses
BR0114619A (pt) 2000-10-11 2005-12-13 Esperion Therapeutics Inc Composto, composição farmacêutica, métodos para tratar ou prevenir uma doença cardiovascular, uma dislipidemia, uma dislipoproteinemia, um distúrbio do metabolismo da glicose, trombótico e associado com o receptor ativado do proliferador de peroxissoma, a doença de alzheimer, a sìndrome x ou sìndrome metabólica, a septicemia, a obesidade, pancreatite, a hipertensão, doença renal, câncer, a inflamação e a impotência, em um paciente e para reduzir o teor de gordura da carne em animal de criação e de colesterol de ovos de aves domésticas
US7304093B2 (en) * 2000-10-11 2007-12-04 Esperion Therapeutics, Inc. Ketone compounds and compositions for cholesterol management and related uses
US20040192771A1 (en) * 2001-10-11 2004-09-30 Dasseux Jean-Louis Henri Ether compounds and compositions for cholesterol management and related uses
US20050020694A1 (en) * 2001-10-11 2005-01-27 Dasseux Jean-Louis Henri Sulfide and disulfide compounds and compositions for cholesterol management and related uses
US20040204502A1 (en) * 2001-10-11 2004-10-14 Dasseux Jean-Louis Henri Sulfoxide and bis-sulfoxide compounds and compositions for cholesterol management and related uses
BR0309152A (pt) * 2002-04-10 2007-01-30 Esperion Therapeutics Inc composto ou sais, solvatos, hidratos ou pró-drogas deste farmaceuticamente aceitáveis, composição, métodos para tratar ou prevenir uma doença ou condição, uma doença cardiovascular, uma dislipidemia, a hipertensão, o cáncer, a inflamação, e a impotência em um paciente, forma de dosagem unitária, e, método para identificar um composto útil para tratar ou prevenir uma condição em um paciente
EP2404890B1 (en) * 2003-01-23 2017-07-26 Esperion Therapeutics Inc. Hydroxyl compounds and compositions for cholesterol management and related uses
WO2005068412A1 (en) * 2003-12-24 2005-07-28 Esperion Therapeutics, Inc. Ketone compounds and compositions for cholesterol management and related uses
CN103848726B (zh) * 2012-12-09 2017-09-05 河北凯盛医药科技有限公司 一种高纯度二羟二丁基醚及其制备方法
CN103304383B (zh) * 2013-06-18 2015-04-08 重庆医科大学 保胆健素的新合成方法
CN103333057A (zh) * 2013-06-24 2013-10-02 大连理工大学 一种二羟基二丁醚的制备方法
CN103319316B (zh) * 2013-06-24 2015-06-10 大连理工大学 一种二羟基二丁醚的绿色制备方法
CN104230674A (zh) * 2014-08-28 2014-12-24 成都邦泽生物医药科技有限公司 一种二羟基二丁醚的制备方法
KR102370582B1 (ko) 2015-03-13 2022-03-04 에스페리온 테라피유틱스 인코포레이티드 Ｅｔｃ1002 및 에제티미브를 포함하는 고정 용량 조합 및 제형 및 심혈관 질환의 치료 또는 이의 위험의 감소 방법
MA41793A (fr) 2015-03-16 2018-01-23 Esperion Therapeutics Inc Associations de doses fixes comprenant du etc1002 et une ou plusieurs statines permettant de traiter ou de réduire un risque cardiovasculaire
CN115429784A (zh) 2019-06-21 2022-12-06 艾斯柏伦治疗公司 制备贝派地酸及其组合物的方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT957008B (it) * 1967-11-09 1973-10-10 Luso Farmaco Inst Processo per la preparazione di eteri simmetrici di glicoli re canti ossidrili primari e secon dari
DE2218935C3 (de) * 1972-04-19 1980-01-31 Basf Ag, 6700 Ludwigshafen Verfahren zur Herstellung von wäßrigen Lösungen von N-Vinylpyrrolidonpolymerisaten

Also Published As

Publication number Publication date
DE3419947C2 (cg-RX-API-DMAC10.html) 1987-11-26
GB8411356D0 (en) 1984-06-06
IT8321352A0 (it) 1983-05-30
JPS604146A (ja) 1985-01-10
GB2142623A (en) 1985-01-23
ES8507449A1 (es) 1985-10-01
BE899790A (fr) 1984-11-30
IT8321352A1 (it) 1984-11-30
GB2142623B (en) 1987-04-15
DE3419947A1 (de) 1984-12-06
JPS6241702B2 (cg-RX-API-DMAC10.html) 1987-09-04
FR2547813A1 (fr) 1984-12-28
US4584321A (en) 1986-04-22
IT1164254B (it) 1987-04-08
ES532802A0 (es) 1985-10-01

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