DK522883A - 2-heterocyclylthio-alkyl-2-penem-forbindelser samt deres fremstilling og anvendelse - Google Patents

2-heterocyclylthio-alkyl-2-penem-forbindelser samt deres fremstilling og anvendelse Download PDF

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Publication number
DK522883A
DK522883A DK522883A DK522883A DK522883A DK 522883 A DK522883 A DK 522883A DK 522883 A DK522883 A DK 522883A DK 522883 A DK522883 A DK 522883A DK 522883 A DK522883 A DK 522883A
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DK
Denmark
Prior art keywords
heterocyclylthio
alkyl
preparation
penem compounds
penem
Prior art date
Application number
DK522883A
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English (en)
Other versions
DK522883D0 (da
Inventor
Marc Lang
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of DK522883D0 publication Critical patent/DK522883D0/da
Publication of DK522883A publication Critical patent/DK522883A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/0803—Compounds with Si-C or Si-Si linkages
    • C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/568—Four-membered rings

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK522883A 1982-11-16 1983-11-15 2-heterocyclylthio-alkyl-2-penem-forbindelser samt deres fremstilling og anvendelse DK522883A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH667182 1982-11-16

Publications (2)

Publication Number Publication Date
DK522883D0 DK522883D0 (da) 1983-11-15
DK522883A true DK522883A (da) 1984-05-17

Family

ID=4313203

Family Applications (1)

Application Number Title Priority Date Filing Date
DK522883A DK522883A (da) 1982-11-16 1983-11-15 2-heterocyclylthio-alkyl-2-penem-forbindelser samt deres fremstilling og anvendelse

Country Status (16)

Country Link
US (1) US4616007A (da)
EP (1) EP0112283B1 (da)
JP (1) JPS59101493A (da)
KR (1) KR840006664A (da)
AU (1) AU2138983A (da)
DD (1) DD214132A5 (da)
DE (1) DE3372968D1 (da)
DK (1) DK522883A (da)
ES (1) ES8607971A1 (da)
FI (1) FI834140A7 (da)
GR (1) GR79432B (da)
IL (1) IL70233A0 (da)
NO (1) NO834190L (da)
NZ (1) NZ206273A (da)
PT (1) PT77659B (da)
ZA (1) ZA838463B (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0003960B1 (de) * 1978-02-02 1983-06-29 Ciba-Geigy Ag 6-Substituierte Thia-Azaverbindungen, ihre Herstellung und diese enthaltende pharmazeutische Präparate
EP0184844A1 (en) * 1984-12-13 1986-06-18 Merck & Co. Inc. 1-Methylcarbapenems having a 2-position substituent joined through an alkylenethio bridge
EP0186057A1 (en) * 1984-12-13 1986-07-02 Merck & Co. Inc. Carbapenems having a 2-position substituent joined through an alkyleneheteroatom bridge
DE69423424T2 (de) * 1993-11-15 2006-08-10 Kureha Corp. Esculetinderivate, Verfahren zu deren Herstellung und deren Verwendung als pharmazeutische Zusammensetzungen

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4168314A (en) * 1977-11-17 1979-09-18 Merck & Co., Inc. 6-(1'-Hydroxyethyl)-2-aminoethylthio-pen-2-em-3-carboxylic acid
EP0003960B1 (de) * 1978-02-02 1983-06-29 Ciba-Geigy Ag 6-Substituierte Thia-Azaverbindungen, ihre Herstellung und diese enthaltende pharmazeutische Präparate
JPS5625110A (en) * 1978-12-18 1981-03-10 Bristol Myers Co Antibacterial
US4272437A (en) * 1978-12-18 1981-06-09 Bristol-Myers Company Antibacterial agents, and 4-thio azetidinone intermediates
NL192265C (nl) * 1979-02-24 1997-04-03 Erba Carlo Spa Penemcarbonzuur-verbindingen en farmaceutische preparaten die deze verbindingen bevatten.
IT1190842B (it) * 1981-06-30 1988-02-24 Erba Farmitalia Via di sintesi di derivati otticamente attivi dell'acido 2-penem-3-carbossilico
JPS588084A (ja) * 1981-07-08 1983-01-18 Takeda Chem Ind Ltd (6r)−置換−(5r)−ペネム−3−カルボン酸誘導体およびその製造法

Also Published As

Publication number Publication date
IL70233A0 (en) 1984-02-29
JPS59101493A (ja) 1984-06-12
FI834140L (fi) 1984-05-17
EP0112283A1 (de) 1984-06-27
ES527260A0 (es) 1986-06-01
NO834190L (no) 1984-05-18
DK522883D0 (da) 1983-11-15
DD214132A5 (de) 1984-10-03
KR840006664A (ko) 1984-12-01
AU2138983A (en) 1984-05-24
PT77659A (en) 1983-12-01
PT77659B (en) 1986-07-17
ZA838463B (en) 1984-06-27
EP0112283B1 (de) 1987-08-12
ES8607971A1 (es) 1986-06-01
DE3372968D1 (en) 1987-09-17
GR79432B (da) 1984-10-22
NZ206273A (en) 1986-04-11
FI834140A0 (fi) 1983-11-11
FI834140A7 (fi) 1984-05-17
US4616007A (en) 1986-10-07

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