IL70233A0 - 2-heterocyclylthioalkyl-2-penem compounds,their manufacture and pharmaceutical compositions containing them - Google Patents

2-heterocyclylthioalkyl-2-penem compounds,their manufacture and pharmaceutical compositions containing them

Info

Publication number
IL70233A0
IL70233A0 IL70233A IL7023383A IL70233A0 IL 70233 A0 IL70233 A0 IL 70233A0 IL 70233 A IL70233 A IL 70233A IL 7023383 A IL7023383 A IL 7023383A IL 70233 A0 IL70233 A0 IL 70233A0
Authority
IL
Israel
Prior art keywords
heterocyclylthioalkyl
manufacture
pharmaceutical compositions
compositions containing
penem compounds
Prior art date
Application number
IL70233A
Other languages
English (en)
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of IL70233A0 publication Critical patent/IL70233A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/0803—Compounds with Si-C or Si-Si linkages
    • C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/568—Four-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IL70233A 1982-11-16 1983-11-14 2-heterocyclylthioalkyl-2-penem compounds,their manufacture and pharmaceutical compositions containing them IL70233A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH667182 1982-11-16

Publications (1)

Publication Number Publication Date
IL70233A0 true IL70233A0 (en) 1984-02-29

Family

ID=4313203

Family Applications (1)

Application Number Title Priority Date Filing Date
IL70233A IL70233A0 (en) 1982-11-16 1983-11-14 2-heterocyclylthioalkyl-2-penem compounds,their manufacture and pharmaceutical compositions containing them

Country Status (16)

Country Link
US (1) US4616007A (da)
EP (1) EP0112283B1 (da)
JP (1) JPS59101493A (da)
KR (1) KR840006664A (da)
AU (1) AU2138983A (da)
DD (1) DD214132A5 (da)
DE (1) DE3372968D1 (da)
DK (1) DK522883A (da)
ES (1) ES8607971A1 (da)
FI (1) FI834140A7 (da)
GR (1) GR79432B (da)
IL (1) IL70233A0 (da)
NO (1) NO834190L (da)
NZ (1) NZ206273A (da)
PT (1) PT77659B (da)
ZA (1) ZA838463B (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0003960B1 (de) * 1978-02-02 1983-06-29 Ciba-Geigy Ag 6-Substituierte Thia-Azaverbindungen, ihre Herstellung und diese enthaltende pharmazeutische Präparate
EP0184844A1 (en) * 1984-12-13 1986-06-18 Merck & Co. Inc. 1-Methylcarbapenems having a 2-position substituent joined through an alkylenethio bridge
EP0186057A1 (en) * 1984-12-13 1986-07-02 Merck & Co. Inc. Carbapenems having a 2-position substituent joined through an alkyleneheteroatom bridge
DE69423424T2 (de) * 1993-11-15 2006-08-10 Kureha Corp. Esculetinderivate, Verfahren zu deren Herstellung und deren Verwendung als pharmazeutische Zusammensetzungen

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4168314A (en) * 1977-11-17 1979-09-18 Merck & Co., Inc. 6-(1'-Hydroxyethyl)-2-aminoethylthio-pen-2-em-3-carboxylic acid
EP0003960B1 (de) * 1978-02-02 1983-06-29 Ciba-Geigy Ag 6-Substituierte Thia-Azaverbindungen, ihre Herstellung und diese enthaltende pharmazeutische Präparate
JPS5625110A (en) * 1978-12-18 1981-03-10 Bristol Myers Co Antibacterial
US4272437A (en) * 1978-12-18 1981-06-09 Bristol-Myers Company Antibacterial agents, and 4-thio azetidinone intermediates
NL192265C (nl) * 1979-02-24 1997-04-03 Erba Carlo Spa Penemcarbonzuur-verbindingen en farmaceutische preparaten die deze verbindingen bevatten.
IT1190842B (it) * 1981-06-30 1988-02-24 Erba Farmitalia Via di sintesi di derivati otticamente attivi dell'acido 2-penem-3-carbossilico
JPS588084A (ja) * 1981-07-08 1983-01-18 Takeda Chem Ind Ltd (6r)−置換−(5r)−ペネム−3−カルボン酸誘導体およびその製造法

Also Published As

Publication number Publication date
JPS59101493A (ja) 1984-06-12
FI834140L (fi) 1984-05-17
EP0112283A1 (de) 1984-06-27
ES527260A0 (es) 1986-06-01
DK522883A (da) 1984-05-17
NO834190L (no) 1984-05-18
DK522883D0 (da) 1983-11-15
DD214132A5 (de) 1984-10-03
KR840006664A (ko) 1984-12-01
AU2138983A (en) 1984-05-24
PT77659A (en) 1983-12-01
PT77659B (en) 1986-07-17
ZA838463B (en) 1984-06-27
EP0112283B1 (de) 1987-08-12
ES8607971A1 (es) 1986-06-01
DE3372968D1 (en) 1987-09-17
GR79432B (da) 1984-10-22
NZ206273A (en) 1986-04-11
FI834140A0 (fi) 1983-11-11
FI834140A7 (fi) 1984-05-17
US4616007A (en) 1986-10-07

Similar Documents

Publication Publication Date Title
IL68620A0 (en) Bicyclic compounds,their manufacture and pharmaceutical compositions containing them
IL68618A0 (en) Heterocyclic compounds,their manufacture and pharmaceutical compositions containing them
IL65056A0 (en) Imidazodiazepines,their manufacture and pharmaceutical compositions containing them
IL67826A0 (en) Pyrazolooxazines,pyrazolothiazines and pyrazoloquinolines,their preparation and pharmaceutical compositions containing them
IL69438A0 (en) Phenethanolamines,their manufacture and pharmaceutical compositions containing them
IL64847A0 (en) Hexapyranose compounds,their manufacture and pharmaceutical compositions containing them
IL70365A0 (en) Substituted tetrapeptides,their manufacture and pharmaceutical compositions containing them
IL68804A0 (en) Amides,their manufacture and pharmaceutical compositions containing them
ZM9283A1 (en) Substituted phenylsulfonyloxybenzimidazolecarbamates,processes for their preparation and pharmaceutical compositions containing the same
IL62960A0 (en) Imidazoazole compounds,their production and pharmaceutical compositions containing them
IL68323A0 (en) Phenoxyalkylcarboxylic acid derivatives,their manufacture and pharmaceutical compositions containing them
IL68497A0 (en) Benzoazacycloalkyl-spiro-imidazolidines,their preparation and pharmaceutical compositions containing them
IL68586A0 (en) 4-aryl-4-piperidinecarbinols,their preparation and pharmaceutical compositions containing them
IL68635A (en) Phenethanolamine derivatives,their manufacture and pharmaceutical compositions containing them
IL68699A0 (en) 3-phenoxy-1-azetidinecarboxamides,their preparation and pharmaceutical compositions containing them
IL68576A0 (en) Azepinoindoles,their production and pharmaceutical compositions containing them
IL67284A (en) N-substituted-2-pyridylindoles,their manufacture and pharmaceutical compositions containing them
IL64489A0 (en) Benzodiazepine compounds,their preparation and pharmaceutical compositions containing them
IL70189A (en) 2-piperazinyl-quinazoline derivatives,their proeuction and pharmaceutical compositions containing them
IL70508A (en) Pharmaceutical compositions containing aralkyltriazole derivatives,some such novel compounds and their preparation
IL70229A0 (en) 2-penem derivatives,their manufacture and pharmaceutical compositions containing them
IL67813A0 (en) Benzothienylallylamines,their production and pharmaceutical compositions containing them
IL63595A (en) Diaryl-imidazole compounds,their manufacture and pharmaceutical compositions containing them
IL72831A0 (en) 2-aminomethyl-penem compounds,their preparation and pharmaceutical compositions containing them
IL62592A0 (en) Phenyl-quinolizidines,their manufacture and pharmaceutical compositions containing them