FR2530243A1 - Procede de preparation de derives de la 1,5-benzothiazepine - Google Patents

Procede de preparation de derives de la 1,5-benzothiazepine Download PDF

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Publication number
FR2530243A1
FR2530243A1 FR8212318A FR8212318A FR2530243A1 FR 2530243 A1 FR2530243 A1 FR 2530243A1 FR 8212318 A FR8212318 A FR 8212318A FR 8212318 A FR8212318 A FR 8212318A FR 2530243 A1 FR2530243 A1 FR 2530243A1
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FR
France
Prior art keywords
compound
formula
salt
process according
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR8212318A
Other languages
English (en)
French (fr)
Other versions
FR2530243B1 (enExample
Inventor
Susumu Nagao
Katsuhiko Kurabayashi
Nobuyuki Futamura
Hidefumi Kinoshita
Toshio Takahashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Pharma Corp
Original Assignee
Tanabe Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co Ltd filed Critical Tanabe Seiyaku Co Ltd
Publication of FR2530243A1 publication Critical patent/FR2530243A1/fr
Application granted granted Critical
Publication of FR2530243B1 publication Critical patent/FR2530243B1/fr
Granted legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR8212318A 1982-07-09 1982-07-13 Procede de preparation de derives de la 1,5-benzothiazepine Granted FR2530243A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/396,734 US4416819A (en) 1982-07-09 1982-07-09 Process for preparing 1,5-benzothiazephine derivatives

Publications (2)

Publication Number Publication Date
FR2530243A1 true FR2530243A1 (fr) 1984-01-20
FR2530243B1 FR2530243B1 (enExample) 1985-04-19

Family

ID=23568426

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8212318A Granted FR2530243A1 (fr) 1982-07-09 1982-07-13 Procede de preparation de derives de la 1,5-benzothiazepine

Country Status (6)

Country Link
US (1) US4416819A (enExample)
EP (1) EP0098892B1 (enExample)
AT (1) AT380015B (enExample)
CA (1) CA1177074A (enExample)
FR (1) FR2530243A1 (enExample)
SE (1) SE449611B (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2642425A1 (fr) * 1989-01-30 1990-08-03 Sanofi Sa Procede de preparation de derives de benzothiazepine-1,5 one-4

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4477464A (en) * 1983-02-10 1984-10-16 Ciba-Geigy Corporation Hetero-benzazepine derivatives and their pharmaceutical use
US4490292A (en) * 1983-10-07 1984-12-25 Hamari Chemicals, Ltd. 1,5-Benzothiazepine derivatives and production thereof
IL71538A (en) * 1984-04-13 1987-07-31 Abic Ltd Process for the preparation of benzothiazepine derivatives
JPS6450872A (en) * 1987-08-21 1989-02-27 Tanabe Seiyaku Co Production of 1,5-benzothiazepine derivative
JPS6445376A (en) * 1987-08-12 1989-02-17 Tanabe Seiyaku Co Production of 1,5-benzothiazepine derivative
IT1217988B (it) * 1988-01-28 1990-03-30 Ind Chimica Profarmaco Spa Procedimento per la risoluzione ottica di un pacemo
FR2630107B1 (fr) * 1988-04-19 1990-06-08 Synthelabo Procede de preparation du (+) - (2s,3s) (amino-2 phenyl)thio)-3 hydroxy-2 (methoxy-4 phenyl)-3 propionate de methyle
US5008433A (en) * 1988-05-18 1991-04-16 Marion Laboratories, Inc. 2-hydroxy-3-(4-methoxyphenyl)-3-(2-aminophenylthio)propionic acid, 8'-phenylmenthyl ester, especially for diltiazem
US4908469A (en) * 1988-05-18 1990-03-13 Marion Laboratories, Inc. 2-Hydroxy-propanoic acid acyclic alkyl esters for benzothiazepines
IT1226300B (it) * 1988-07-26 1990-12-27 Zambon Spa Processo per la preparazione di intermedi per la sintesi del diltiazem.
FR2641535B1 (fr) * 1989-01-11 1991-03-15 Synthelabo Procede de preparation de (+) - (2s, 3s)-hydroxy-3 (methoxy-4 phenyl)-2 dihydro-2,3 5h-benzothiazepine-1,5 one-4
USRE34935E (en) * 1989-01-11 1995-05-09 Synthelabo Method for preparing (+)-(2S,3S)-3-hydroxy-2-(4-methoxyphenyl)-2,3-dihydro-5H-1,5-benzothiazepine-4-one and chlorinated derivatives thereof
IT1230057B (it) * 1989-04-13 1991-09-27 Zambon Spa Processo di risoluzione di intermedi utili per la preparazione di 1,5-benzotiazepine
DK0431121T3 (da) * 1989-06-30 1993-10-11 Richter Gedeon Vegyeszet Fremgangsmåde til opspaltning af threo-((2-aminophenyl)-thio)-2-hydroxy-3-(4-methoxyphenyl)- propionsyre
IT1234387B (it) * 1989-07-12 1992-05-18 Zambon Spa Processo di purificazione di intermedi utili nella preparazione del diltiazem
IT1232306B (it) * 1989-07-27 1992-01-28 Zambon Spa Processo di risoluzione di intermedi utili per la preparazione del diltiazem
IT1237526B (it) * 1989-12-06 1993-06-08 Zambon Spa Processo di preparazione di un intermedio per il diltiazem
IT1240651B (it) * 1990-05-17 1993-12-17 Zambon Spa Processo per la risoluzione di derivati glicidici
IL102592A (en) * 1992-07-21 1996-09-12 Teva Pharma Optical resolution of threo-2-hydroxy-3-(2-aminophenylthio)-3-(4-methoxyphenyl)-propionic acid
DE4313413A1 (de) * 1993-04-23 1994-10-27 Basf Ag 3-(Het)aryloxy(thio)-Carbonsäurederivate, Verfahren und Zwischenprodukte zu ihrer Herstellung
US6130352A (en) * 1995-01-27 2000-10-10 Council Of Scientific & Industrial Research Method for producing (+) (2S,3S)-3-(2-aminophenylthio)-2-hydroxy-3(4'-methoxyphenyl)-propionic acid
FI97725C (fi) * 1995-02-17 1997-02-10 Orion Yhtymae Oy Menetelmä diltiatseemin valmistamiseksi
IT1295376B1 (it) * 1997-10-22 1999-05-12 Zambon Spa Processo per il riciclo di un sottoprodotto della sintesi del diltiazem
US6635277B2 (en) 2000-04-12 2003-10-21 Wockhardt Limited Composition for pulsatile delivery of diltiazem and process of manufacture
WO2014030106A2 (en) 2012-08-18 2014-02-27 Unimark Remedies Ltd. Process for preparation of optically active (2r,3s)-3-(4- methoxyphenyl)glycidic acid methyl ester and cis lactam and uses thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2034493A1 (enExample) * 1969-01-25 1970-12-11 Tanabe Seiyaku Co
GB1236467A (en) * 1967-10-28 1971-06-23 Tanabe Seiyaku Co Benzothiazepine derivatives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3155649A (en) * 1962-07-11 1964-11-03 Olin Mathieson Benzothiazocinones, related compounds and their preparation
US3562257A (en) * 1967-10-28 1971-02-09 Tanabe Seiyaku Co Benzothiazepine derivatives
FR2360124A1 (fr) * 1976-07-30 1978-02-24 Amiens Const Electro Mecan Procede de controle de commutation de la puissance de chauffage dans un appareil electrodomestique a programmateur et dispositif pour la mise en oeuvre dudit procede
JPS5343517A (en) * 1976-10-01 1978-04-19 Eru Pii Eru Kk Cine film connecting tape
JPH0643785A (ja) * 1992-07-23 1994-02-18 Canon Inc 画像形成装置

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1236467A (en) * 1967-10-28 1971-06-23 Tanabe Seiyaku Co Benzothiazepine derivatives
FR2034493A1 (enExample) * 1969-01-25 1970-12-11 Tanabe Seiyaku Co

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2642425A1 (fr) * 1989-01-30 1990-08-03 Sanofi Sa Procede de preparation de derives de benzothiazepine-1,5 one-4
EP0381570A1 (fr) * 1989-01-30 1990-08-08 Elf Sanofi Procédé de préparation de dérivés de benzothiazépine-1,5 one-4

Also Published As

Publication number Publication date
FR2530243B1 (enExample) 1985-04-19
SE449611B (sv) 1987-05-11
EP0098892A1 (en) 1984-01-25
CA1177074A (en) 1984-10-30
ATA267882A (de) 1985-08-15
SE8204181D0 (sv) 1982-07-06
EP0098892B1 (en) 1987-10-28
AT380015B (de) 1986-03-25
SE8204181L (sv) 1984-01-07
US4416819A (en) 1983-11-22

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