FR2529201B1 - Composes polyethyleniques, procede pour leur preparation et leurs utilisations therapeutiques, notamment en tant qu'agents antitumeurs - Google Patents

Composes polyethyleniques, procede pour leur preparation et leurs utilisations therapeutiques, notamment en tant qu'agents antitumeurs

Info

Publication number
FR2529201B1
FR2529201B1 FR8310319A FR8310319A FR2529201B1 FR 2529201 B1 FR2529201 B1 FR 2529201B1 FR 8310319 A FR8310319 A FR 8310319A FR 8310319 A FR8310319 A FR 8310319A FR 2529201 B1 FR2529201 B1 FR 2529201B1
Authority
FR
France
Prior art keywords
preparation
therapeutic uses
tumor agents
polyethylenic
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8310319A
Other languages
English (en)
French (fr)
Other versions
FR2529201A1 (fr
Inventor
Ernst Peter Krebs
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of FR2529201A1 publication Critical patent/FR2529201A1/fr
Application granted granted Critical
Publication of FR2529201B1 publication Critical patent/FR2529201B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/74—Unsaturated compounds containing —CHO groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/46—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid
    • C07C57/50—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid containing condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/738—Esters of keto-carboxylic acids or aldehydo-carboxylic acids

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FR8310319A 1982-06-24 1983-06-22 Composes polyethyleniques, procede pour leur preparation et leurs utilisations therapeutiques, notamment en tant qu'agents antitumeurs Expired FR2529201B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH3889/82A CH651007A5 (de) 1982-06-24 1982-06-24 Polyenverbindungen.

Publications (2)

Publication Number Publication Date
FR2529201A1 FR2529201A1 (fr) 1983-12-30
FR2529201B1 true FR2529201B1 (fr) 1988-08-19

Family

ID=4265678

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8310319A Expired FR2529201B1 (fr) 1982-06-24 1983-06-22 Composes polyethyleniques, procede pour leur preparation et leurs utilisations therapeutiques, notamment en tant qu'agents antitumeurs

Country Status (19)

Country Link
JP (1) JPS5910547A (enrdf_load_stackoverflow)
AT (1) AT392780B (enrdf_load_stackoverflow)
AU (1) AU560027B2 (enrdf_load_stackoverflow)
BE (1) BE897118A (enrdf_load_stackoverflow)
CA (1) CA1276032C (enrdf_load_stackoverflow)
CH (1) CH651007A5 (enrdf_load_stackoverflow)
DE (1) DE3321662A1 (enrdf_load_stackoverflow)
DK (1) DK159392C (enrdf_load_stackoverflow)
FR (1) FR2529201B1 (enrdf_load_stackoverflow)
GB (2) GB2122200B (enrdf_load_stackoverflow)
IE (1) IE55285B1 (enrdf_load_stackoverflow)
IL (1) IL69028A0 (enrdf_load_stackoverflow)
IT (1) IT1212753B (enrdf_load_stackoverflow)
LU (1) LU84870A1 (enrdf_load_stackoverflow)
NL (1) NL8302136A (enrdf_load_stackoverflow)
NZ (1) NZ204628A (enrdf_load_stackoverflow)
PH (1) PH20070A (enrdf_load_stackoverflow)
SE (1) SE454984B (enrdf_load_stackoverflow)
ZA (1) ZA834473B (enrdf_load_stackoverflow)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1203634B (it) * 1984-08-13 1989-02-15 Oreal Derivati 1-sostituiti del 4-metossi-2,3,6-trimetilbenzene loro procedimento di preparazione e composizioni medicamentose e cosmetiche che li contengono
FR2621912B1 (fr) * 1987-10-16 1990-03-02 Oreal Nouveaux derives du norbornane, leur procede de preparation et compositions cosmetique et medicamenteuse les contenant
DE4033568A1 (de) * 1990-10-22 1992-04-23 Henkel Kgaa Bicyclische verbindungen mit antiseborrhoischer wirkung
ATE181052T1 (de) * 1994-08-10 1999-06-15 Hoffmann La Roche Retinoesäure x-rezeptor liganden

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1070173B (de) * 1959-12-03 Badische Anilin- S. Soda-Fabrik Aktiengesellschaft, Ludwigshafen / Rhein Verfahren zur Herstellung von 13-[2',6',6'-Trimethylcyclohexen-(l')-yl-(l')]-3,7,ll-trimethyltridecahexaen - (2,4,6,8,10,12) - säureil) bzw. deren Estern
DE923252C (de) * 1944-09-23 1955-02-07 Schering Ag Verfahren zur Herstellung einer Polyencarbonsaeure der Formel CHO
AT207831B (de) * 1957-11-27 1960-02-25 Hoffmann La Roche Verfahren zur Herstellung von Polyencarbonsäureestern und deren Verseifungsprodukten
AT222103B (de) * 1958-08-07 1962-07-10 Bayer Ag Verfahren zur Herstellung von 2-trans-β-Jonylidenessigsäure
CH529742A (de) * 1970-02-02 1972-10-31 Hoffmann La Roche Verfahren zur Herstellung von Vitamin-A-Säureamiden
AT340902B (de) * 1974-03-29 1978-01-10 Hoffmann La Roche Verfahren zur herstellung von neuen polyenverbindungen
DE2456959A1 (de) * 1974-12-03 1976-06-16 Basf Ag 4-(e)- und 4-(z)-7-methyl-9-(2,6,6trimethyl-1-cyclohexen-1-yl)-nona-2,4,6,8tetraencarbonsaeure, ihre derivate und diese enthaltende zubereitungen
CH624373A5 (en) * 1975-11-14 1981-07-31 Hoffmann La Roche Process for the preparation of polyene compounds
CA1111441A (en) * 1976-12-20 1981-10-27 Werner Bollag Polyene compounds
LU77254A1 (enrdf_load_stackoverflow) * 1977-05-04 1979-01-18
US4169103A (en) * 1978-04-12 1979-09-25 Hoffmann-La Roche Inc. Nonatetraenoic acid derivatives
DE2843884A1 (de) * 1978-10-07 1980-04-24 Basf Ag Mittel, enthaltend 2-(retinyliden)- malonsaeurederivate

Also Published As

Publication number Publication date
GB2156351A (en) 1985-10-09
IE831471L (en) 1983-12-24
DE3321662A1 (de) 1983-12-29
DK159392B (da) 1990-10-08
FR2529201A1 (fr) 1983-12-30
AU1620183A (en) 1984-01-05
IT1212753B (it) 1989-11-30
DK159392C (da) 1991-03-04
ATA230583A (de) 1990-11-15
SE8303539D0 (sv) 1983-06-20
DK287083D0 (da) 1983-06-21
NL8302136A (nl) 1984-01-16
SE8303539L (sv) 1983-12-25
GB2156351B (en) 1986-05-14
AU560027B2 (en) 1987-03-26
PH20070A (en) 1986-09-18
GB8510717D0 (en) 1985-06-05
GB8317129D0 (en) 1983-07-27
JPH0441134B2 (enrdf_load_stackoverflow) 1992-07-07
AT392780B (de) 1991-06-10
IL69028A0 (en) 1983-10-31
BE897118A (fr) 1983-12-23
CH651007A5 (de) 1985-08-30
JPS5910547A (ja) 1984-01-20
ZA834473B (en) 1984-03-28
LU84870A1 (de) 1985-03-29
NZ204628A (en) 1985-07-31
CA1276032C (en) 1990-11-06
IT8321721A0 (it) 1983-06-21
IE55285B1 (en) 1990-08-01
GB2122200B (en) 1986-05-08
GB2122200A (en) 1984-01-11
DE3321662C2 (enrdf_load_stackoverflow) 1992-11-26
SE454984B (sv) 1988-06-13
DK287083A (da) 1983-12-25

Similar Documents

Publication Publication Date Title
BE890024A (fr) Derives tricycliques de l'imidazole, leur preparation et leurs utilisations therapeutiques
FR2555584B1 (fr) Derives de l'acide fluoro-6-dihydro-1,4-oxo-4-piperazinyl substitue-7-quinoline-carboxylique-3 et procede pour leur preparation et compositions pharmaceutiques a action anti-bacteriennes a base desdits derives
FR2303058A1 (fr) Procede d'encollage et de collage, notamment pour le soudage de semelles de chaussures
FR2523582B1 (fr) Nouvelles 1h-pyrazolo(1,5-a)pyrimidines substituees, utiles notamment comme medicaments anti-inflammatoires et analgesiques, et procede pour leur preparation
BE890002A (fr) Procede d'acceleration de la dissolution de substances medicamenteuses lyophilisees difficilement solubles
FR2303802A1 (fr) Composes d'imidazolium quaternaire, leur procede de preparation et compositions, notamment microbicides les contenant
FR2585018B1 (fr) Poly-4-aminopyrrole-2-carboxamides et derives, procede pour leur preparation et leurs utilisations therapeutiques
PT66174A (fr) Procede pour la preparation de derives de ditiole-1,2 et de compositions qu'en contiennent
MC1440A1 (fr) Derives de la pyrrolidine,sa preparation et ses utilisations therapeutiques pour le traitement de l'insuffisance cerebrale
FR2560195B1 (fr) Derives d'alanyl-proline, leur procede de preparation et leurs applications pharmaceutiques
FR2496106B1 (fr) Derives d'acide 7-acylaminocephalosporanique et procede pour leur preparation
FR2529201B1 (fr) Composes polyethyleniques, procede pour leur preparation et leurs utilisations therapeutiques, notamment en tant qu'agents antitumeurs
BE892602A (fr) Esters de mercaptoacyl-carnitines, procede pour leur preparation et leurs utilisations therapeutiques
BE883943A (fr) Derives de l'enkaphaline, leur preparation et leurs utilisations therapeutiques, notamment comme analgesiques
FR2547822B1 (fr) Acylpiperazinoquinazolines substituees utiles comme medicaments et procede pour leur preparation
FR2529551B1 (fr) Derives d'eburnane-oxime, procede pour leur preparation et compositions pharmaceutiques contenant ces composes
FR2526424B1 (fr) Derives d'acide carbazique, procede pour leur preparation et compositions les contenant
MA20150A1 (fr) Derives de l'acide bicyclo (3,2-1) octane carboxylique et leur procede de preparation et leur application therapeutique.
FR2503150B1 (fr) Mercaptoacyl-carnitines, procede pour leur preparation et leurs utilisations therapeutiques dans le traitement des intoxications et des brulures et en tant qu'agents mucolytiques
FR2510577B1 (fr) Composes organiques azotes extraits de plantes et leurs derives, leur preparation et leurs utilisations therapeutiques, notamment en tant qu'agents antineoplastiques
PT77767B (fr) Procede de preparation de 3',5'-diarabinosides et de compositi-ons pharmaceutiques les contenant
FR2523972B1 (fr) Derives vinyliques substitues de la 1h-pyrazolo-(1,5-a) pyrimidine utiles notamment comme medicaments antiulcerigenes et antisecretoires gastriques et procede de leur preparation
RO76126A2 (ro) Procedeu pentru prepararea acizilor antrachinon 2,6-si-2,7-disulfonici
FR2519638B1 (fr) Derives d'aminopropylaminobleomycine, leurs applications therapeutiques et procede pour leur preparation
FR2529549B1 (fr) Oxime-ethers d'eburnane, procede pour leur preparation et compositions pharmaceutiques qui les contiennent

Legal Events

Date Code Title Description
TP Transmission of property
ST Notification of lapse