FR2525901B1 - Agent de prophylaxie et de traitement des anomalies des lipides sanguins et/ou de l'arteriosclerose, a base d'une enzyme proteolytique - Google Patents

Agent de prophylaxie et de traitement des anomalies des lipides sanguins et/ou de l'arteriosclerose, a base d'une enzyme proteolytique

Info

Publication number
FR2525901B1
FR2525901B1 FR8307188A FR8307188A FR2525901B1 FR 2525901 B1 FR2525901 B1 FR 2525901B1 FR 8307188 A FR8307188 A FR 8307188A FR 8307188 A FR8307188 A FR 8307188A FR 2525901 B1 FR2525901 B1 FR 2525901B1
Authority
FR
France
Prior art keywords
arteriosclerosis
prophylaxis
abnormalities
treatment agent
proteolytic enzyme
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8307188A
Other languages
English (en)
Other versions
FR2525901A1 (fr
Inventor
Shigemi Fujisaki
Takashi Fujisaki
Junichi Yoshida
Yasuhiro Fujisaki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kaken Pharmaceutical Co Ltd
Original Assignee
Kaken Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kaken Pharmaceutical Co Ltd filed Critical Kaken Pharmaceutical Co Ltd
Publication of FR2525901A1 publication Critical patent/FR2525901A1/fr
Application granted granted Critical
Publication of FR2525901B1 publication Critical patent/FR2525901B1/fr
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/482—Serine endopeptidases (3.4.21)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4886—Metalloendopeptidases (3.4.24), e.g. collagenase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/24—Metalloendopeptidases (3.4.24)
    • C12Y304/2404—Serralysin (3.4.24.40)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
FR8307188A 1982-04-30 1983-04-29 Agent de prophylaxie et de traitement des anomalies des lipides sanguins et/ou de l'arteriosclerose, a base d'une enzyme proteolytique Expired FR2525901B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP57071494A JPS58189122A (ja) 1982-04-30 1982-04-30 高脂血症予防治療剤

Publications (2)

Publication Number Publication Date
FR2525901A1 FR2525901A1 (fr) 1983-11-04
FR2525901B1 true FR2525901B1 (fr) 1988-08-26

Family

ID=13462269

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8307188A Expired FR2525901B1 (fr) 1982-04-30 1983-04-29 Agent de prophylaxie et de traitement des anomalies des lipides sanguins et/ou de l'arteriosclerose, a base d'une enzyme proteolytique

Country Status (5)

Country Link
US (1) US4440749A (fr)
JP (1) JPS58189122A (fr)
DE (1) DE3315482A1 (fr)
FR (1) FR2525901B1 (fr)
GB (1) GB2121685B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0676339B2 (ja) * 1985-09-13 1994-09-28 浩 前田 制癌剤
US5116615A (en) * 1989-01-27 1992-05-26 Immunolytics, Inc. Method for treating benign prostatic hypertrophy
ES2072424T3 (es) 1989-01-27 1995-07-16 Immunolytics Inc Formula y metodo para el tratamiento de hipertrofias prostaticas benignas.
JPH02292226A (ja) * 1989-05-08 1990-12-03 Shigemi Fujisaki 障害された神経細胞賦活予防治療剤
NL9201842A (nl) * 1992-10-23 1994-05-16 Teng Hian Khoe Toepassing van een papaine bevattend voedingssupplement voor therapeutische behandeling van AIDS aandoeningen.
GB9403344D0 (en) * 1994-02-22 1994-04-13 Cortecs Ltd Medical application of bromelain
DE102005002255A1 (de) 2005-01-18 2006-07-20 Rehau Ag + Co. Wandanschlussprofil

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB753134A (en) * 1952-09-17 1956-07-18 Nat Drug Co An injectable trypsin containing pharmaceutical composition and method for its production
GB894151A (en) * 1958-01-29 1962-04-18 American Cyanamid Co Preparation of high purity streptokinase
US3224942A (en) * 1962-01-15 1965-12-21 Rorer Inc William H Anti-inflammatory, anti-edema and anti-thrombi drug
DE1249797B (de) * 1963-06-29 1967-09-14 Behringwerke Aktiengesellschaft, Marburg/Lahn Verfahren zur Herstellung von Streptokinase-Präparaten verminderter Antigenität
US3355361A (en) * 1964-10-15 1967-11-28 Sterling Drug Inc Recovery and purification of urokinase
GB1139991A (en) * 1965-07-19 1969-01-15 Armour Pharma Stabilized enzyme composition
GB1185335A (en) * 1967-05-30 1970-03-25 Takeda Chemical Industries Ltd A method for producing Protease
GB1263956A (en) * 1969-09-26 1972-02-16 Ici Ltd Enzymes
GB1274604A (en) * 1971-02-18 1972-05-17 Wilson Pharm & Chem Corp Pancreatin composition and method of preparation
AU469815B2 (en) * 1971-04-14 1973-10-18 Anti-inflammatory compositions
JPS5443074B1 (fr) * 1971-04-14 1979-12-18
BE786788A (fr) * 1971-07-27 1973-01-26 Rhone Poulenc Sa Nouvelle enzyme thrombolytique et sa preparation par fermentation d'un streptomyces
JPS5039151B2 (fr) * 1972-09-02 1975-12-15
GB1479268A (en) * 1973-07-05 1977-07-13 Beecham Group Ltd Pharmaceutical compositions
GB1448276A (en) * 1973-09-15 1976-09-02 Eisai Co Ltd Elastase and methods for using same
US4082612A (en) * 1976-09-24 1978-04-04 Michael Reese Research Foundation Plasminogen activator complex
JPS5473107A (en) * 1977-11-24 1979-06-12 Keigo Takeda Germicide for special coccus *not disinfected one kind of antibiotics*
JPS5543040A (en) * 1978-09-25 1980-03-26 Eisai Co Ltd Immunity raising agent
JPS5826822B2 (ja) * 1979-03-29 1983-06-06 株式会社日立製作所 半導体の気相成長方法
IT1170913B (it) * 1981-04-23 1987-06-03 Manetti & Roberts Italo Brit Procedimento per la produzione di un principio attivo fibrinolitico vasale prodotto enzimatico specifico angiochinasi cosi' ottenuto e sue applicazioni farmaceutiche
JPS5826822U (ja) * 1981-08-17 1983-02-21 株式会社クボタ 刈取収穫機

Also Published As

Publication number Publication date
GB8310184D0 (en) 1983-05-18
FR2525901A1 (fr) 1983-11-04
US4440749A (en) 1984-04-03
JPS58189122A (ja) 1983-11-04
JPH0213647B2 (fr) 1990-04-04
GB2121685A (en) 1984-01-04
GB2121685B (en) 1986-05-21
DE3315482A1 (de) 1984-01-12
DE3315482C2 (fr) 1992-07-16

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Legal Events

Date Code Title Description
TP Transmission of property
ST Notification of lapse