FR2516387A1 - Inhalateur liberant des quantites pre-dosees de principe actif volatil ou entrainable par un excipient volatil contenu dans des microcapsules reparties periodiquement sur un support, ainsi que ledit support et son procede de fabrication - Google Patents

Inhalateur liberant des quantites pre-dosees de principe actif volatil ou entrainable par un excipient volatil contenu dans des microcapsules reparties periodiquement sur un support, ainsi que ledit support et son procede de fabrication Download PDF

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Publication number
FR2516387A1
FR2516387A1 FR8121383A FR8121383A FR2516387A1 FR 2516387 A1 FR2516387 A1 FR 2516387A1 FR 8121383 A FR8121383 A FR 8121383A FR 8121383 A FR8121383 A FR 8121383A FR 2516387 A1 FR2516387 A1 FR 2516387A1
Authority
FR
France
Prior art keywords
microcapsules
support
crushing
volatile
substratum
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR8121383A
Other languages
English (en)
French (fr)
Other versions
FR2516387B1 (enrdf_load_stackoverflow
Inventor
Michel Traisnel
Anne Gayot
Pierre Leterme
Francis Mayne
Elie Leverd
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pierre Fabre SA
Original Assignee
Pierre Fabre SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pierre Fabre SA filed Critical Pierre Fabre SA
Priority to FR8121383A priority Critical patent/FR2516387A1/fr
Publication of FR2516387A1 publication Critical patent/FR2516387A1/fr
Application granted granted Critical
Publication of FR2516387B1 publication Critical patent/FR2516387B1/fr
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0011—Details of inhalators; Constructional features thereof with microcapsules, e.g. several in one dose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0031—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up by bursting or breaking the package, i.e. without cutting or piercing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0046—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
    • A61M15/0048—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged in a plane, e.g. on diskettes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0046—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
    • A61M15/0051—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged on a tape, e.g. strips
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
FR8121383A 1981-11-16 1981-11-16 Inhalateur liberant des quantites pre-dosees de principe actif volatil ou entrainable par un excipient volatil contenu dans des microcapsules reparties periodiquement sur un support, ainsi que ledit support et son procede de fabrication Granted FR2516387A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR8121383A FR2516387A1 (fr) 1981-11-16 1981-11-16 Inhalateur liberant des quantites pre-dosees de principe actif volatil ou entrainable par un excipient volatil contenu dans des microcapsules reparties periodiquement sur un support, ainsi que ledit support et son procede de fabrication

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8121383A FR2516387A1 (fr) 1981-11-16 1981-11-16 Inhalateur liberant des quantites pre-dosees de principe actif volatil ou entrainable par un excipient volatil contenu dans des microcapsules reparties periodiquement sur un support, ainsi que ledit support et son procede de fabrication

Publications (2)

Publication Number Publication Date
FR2516387A1 true FR2516387A1 (fr) 1983-05-20
FR2516387B1 FR2516387B1 (enrdf_load_stackoverflow) 1984-06-29

Family

ID=9264023

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8121383A Granted FR2516387A1 (fr) 1981-11-16 1981-11-16 Inhalateur liberant des quantites pre-dosees de principe actif volatil ou entrainable par un excipient volatil contenu dans des microcapsules reparties periodiquement sur un support, ainsi que ledit support et son procede de fabrication

Country Status (1)

Country Link
FR (1) FR2516387A1 (enrdf_load_stackoverflow)

Cited By (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990013328A1 (en) * 1989-04-28 1990-11-15 Riker Laboratories, Inc. Dry powder inhalation device
WO1990013327A1 (en) * 1989-04-28 1990-11-15 Riker Laboratories, Inc. Dry powder inhalation device
EP0407028A3 (en) * 1989-05-31 1991-03-27 Fisons Plc Medicament inhalation device and formulation
FR2659558A1 (fr) * 1990-03-02 1991-09-20 Glaxo Group Ltd Dispositif d'inhalation.
EP0467172A1 (en) * 1990-07-16 1992-01-22 Promo Pack Sa Multiple single-dose inhaler for medicaments in powder form
EP0469814A1 (en) * 1990-07-31 1992-02-05 Lilly Industries Limited Medicament administering devices
US5176132A (en) * 1989-05-31 1993-01-05 Fisons Plc Medicament inhalation device and formulation
US5192548A (en) * 1990-04-30 1993-03-09 Riker Laboratoires, Inc. Device
WO1993016748A3 (en) * 1992-02-21 1993-12-23 Innovata Biomed Ltd Metering device
WO1994027653A3 (en) * 1993-05-21 1995-02-09 Miris Medical Corp The intrapulmonary delivery of aerosolized aqueous formulations
US5482032A (en) * 1993-07-14 1996-01-09 Astra Aktiebolag Dry powder inhalers
US5507281A (en) * 1990-08-30 1996-04-16 Boehringer Ingelheim Kg Device for initiating a mechanical switching operation in synchronism with the breathing
US5617845A (en) * 1990-08-30 1997-04-08 Boehringer Ingelheim Kg Inhalation device free from propellent gas
WO1997025087A1 (en) * 1996-01-12 1997-07-17 Langridge Investments Llc Dispenser for a therapeutic substance
US5657749A (en) * 1992-09-11 1997-08-19 Glaxo Group Limited Inhalation device
US5709202A (en) * 1993-05-21 1998-01-20 Aradigm Corporation Intrapulmonary delivery of aerosolized formulations
US5819730A (en) * 1993-06-09 1998-10-13 Glaxo Wellcome Australia Ltd. Device for administering pharmaceutical substances
US6378519B1 (en) * 1990-03-02 2002-04-30 Glaxo Group Limited Inhalation device
US6536427B2 (en) 1990-03-02 2003-03-25 Glaxo Group Limited Inhalation device
GB2407042A (en) * 2003-10-17 2005-04-20 Vectura Ltd Pocket blister inhaler with piercing actuator
US7389775B2 (en) 1990-03-02 2008-06-24 Glaxo Group Limited Inhalation device
EP2668970A1 (en) * 2006-10-25 2013-12-04 Novartis AG Powder dispersion apparatus

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3046714A (en) * 1961-03-16 1962-07-31 Leandro J Malicay Method of and apparatus for making seed tape
FR2293221A1 (fr) * 1974-12-03 1976-07-02 Fabre Sa Pierre Appareil inhalateur destine notamment au traitement des coryzas et des sinusites
DE2837040A1 (de) * 1978-08-24 1980-02-28 Siemens Ag Fluessigkeitstransportsystem fuer ein inhalationsgeraet

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3046714A (en) * 1961-03-16 1962-07-31 Leandro J Malicay Method of and apparatus for making seed tape
FR2293221A1 (fr) * 1974-12-03 1976-07-02 Fabre Sa Pierre Appareil inhalateur destine notamment au traitement des coryzas et des sinusites
DE2837040A1 (de) * 1978-08-24 1980-02-28 Siemens Ag Fluessigkeitstransportsystem fuer ein inhalationsgeraet

Cited By (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU644790B2 (en) * 1989-04-28 1993-12-23 Astra Aktiebolag Dry powder inhalation device
WO1990013327A1 (en) * 1989-04-28 1990-11-15 Riker Laboratories, Inc. Dry powder inhalation device
US6012454A (en) * 1989-04-28 2000-01-11 Minnesota Mining And Manufacturing Company Dry powder inhalation device
US5740793A (en) * 1989-04-28 1998-04-21 Astra Aktiebolag Dry powder inhalation device with elongate carrier for power
US5655523A (en) * 1989-04-28 1997-08-12 Minnesota Mining And Manufacturing Company Dry powder inhalation device having deagglomeration/aerosolization structure responsive to patient inhalation
US5619984A (en) * 1989-04-28 1997-04-15 Astra Aktiebolag Dry powder inhalation device having a powder-loaded elongate carrier
WO1990013328A1 (en) * 1989-04-28 1990-11-15 Riker Laboratories, Inc. Dry powder inhalation device
EP0705614A1 (en) * 1989-04-28 1996-04-10 Riker Laboratories, Inc. Dry powder inhalation device
EP0407028A3 (en) * 1989-05-31 1991-03-27 Fisons Plc Medicament inhalation device and formulation
US5628307A (en) * 1989-05-31 1997-05-13 Fisons Plc Medicament inhalation device and formulation
US5176132A (en) * 1989-05-31 1993-01-05 Fisons Plc Medicament inhalation device and formulation
US5538999A (en) * 1989-05-31 1996-07-23 Fisons Plc Medicament inhalation device and formulation
US5590645A (en) * 1990-03-02 1997-01-07 Glaxo Group Limited Inhalation device
US5873360A (en) * 1990-03-02 1999-02-23 Glaxo Group Limited Inhalation device
AP310A (en) * 1990-03-02 1994-01-07 Glaxo Group Ltd Inhalation device.
US5860419A (en) * 1990-03-02 1999-01-19 Glaxo Group Limited Inhalation device
US7389775B2 (en) 1990-03-02 2008-06-24 Glaxo Group Limited Inhalation device
US6792945B2 (en) 1990-03-02 2004-09-21 Glaxo Group Limited Inhalation device
US6536427B2 (en) 1990-03-02 2003-03-25 Glaxo Group Limited Inhalation device
BE1003798A4 (fr) * 1990-03-02 1992-06-16 Glaxo Group Ltd Dispositif d'inhalation.
FR2660550A1 (fr) * 1990-03-02 1991-10-11 Glaxo Group Ltd Conditionnement de medicament pour dispositif d'inhalation.
FR2659558A1 (fr) * 1990-03-02 1991-09-20 Glaxo Group Ltd Dispositif d'inhalation.
AT401007B (de) * 1990-03-02 1996-05-28 Glaxo Group Ltd Inhaliergerät und medikamentenpackung hierfür
US6032666A (en) * 1990-03-02 2000-03-07 Glaxo Group Limited Inhalation device
US6378519B1 (en) * 1990-03-02 2002-04-30 Glaxo Group Limited Inhalation device
GR910100096A (el) * 1990-03-02 1992-06-30 Glaxo Group Ltd Συσκευή εισπνοών.
US5192548A (en) * 1990-04-30 1993-03-09 Riker Laboratoires, Inc. Device
US5207217A (en) * 1990-07-16 1993-05-04 Promo Pack Sa Multiple single-dose inhaler for medicaments in powder form
EP0467172A1 (en) * 1990-07-16 1992-01-22 Promo Pack Sa Multiple single-dose inhaler for medicaments in powder form
EP0469814A1 (en) * 1990-07-31 1992-02-05 Lilly Industries Limited Medicament administering devices
US5617845A (en) * 1990-08-30 1997-04-08 Boehringer Ingelheim Kg Inhalation device free from propellent gas
US5507281A (en) * 1990-08-30 1996-04-16 Boehringer Ingelheim Kg Device for initiating a mechanical switching operation in synchronism with the breathing
GB2278596B (en) * 1992-02-21 1996-05-01 Innovata Biomed Ltd Metering device
WO1993016748A3 (en) * 1992-02-21 1993-12-23 Innovata Biomed Ltd Metering device
US5778873A (en) * 1992-02-21 1998-07-14 Innovata Biomed Limited Metering device for use in transferring a desired volumetric dose of a flowable substance from a storage container
EP0928618A1 (en) * 1992-02-21 1999-07-14 Innovata Biomed Limited Powder inhaler
GB2278596A (en) * 1992-02-21 1994-12-07 Innovata Biomed Ltd Metering device
US5657749A (en) * 1992-09-11 1997-08-19 Glaxo Group Limited Inhalation device
US5718222A (en) * 1993-05-21 1998-02-17 Aradigm Corporation Disposable package for use in aerosolized delivery of drugs
WO1994027653A3 (en) * 1993-05-21 1995-02-09 Miris Medical Corp The intrapulmonary delivery of aerosolized aqueous formulations
US5709202A (en) * 1993-05-21 1998-01-20 Aradigm Corporation Intrapulmonary delivery of aerosolized formulations
US6014969A (en) * 1993-05-21 2000-01-18 Aradigm Corporation Disposable package for use in aerosolized delivery of antibiotics
US6123068A (en) * 1993-05-21 2000-09-26 Aradigm Corporation Systems for the intrapulmonary delivery of aerosolized aqueous formulations
US5544646A (en) * 1993-05-21 1996-08-13 Aradigm Corporation Systems for the intrapulmonary delivery of aerosolized aqueous formulations
US5497763A (en) * 1993-05-21 1996-03-12 Aradigm Corporation Disposable package for intrapulmonary delivery of aerosolized formulations
US5819730A (en) * 1993-06-09 1998-10-13 Glaxo Wellcome Australia Ltd. Device for administering pharmaceutical substances
US5482032A (en) * 1993-07-14 1996-01-09 Astra Aktiebolag Dry powder inhalers
WO1997025087A1 (en) * 1996-01-12 1997-07-17 Langridge Investments Llc Dispenser for a therapeutic substance
GB2407042A (en) * 2003-10-17 2005-04-20 Vectura Ltd Pocket blister inhaler with piercing actuator
GB2407042B (en) * 2003-10-17 2007-10-24 Vectura Ltd Inhaler
US7950389B2 (en) 2003-10-17 2011-05-31 Vectura Delivery Devices Limited Inhaler
US8443798B2 (en) 2003-10-17 2013-05-21 Vectura Delivery Devices Limited Inhaler
US8997737B2 (en) 2003-10-17 2015-04-07 Vectura Delivery Devices Limited Inhaler
EP2668970A1 (en) * 2006-10-25 2013-12-04 Novartis AG Powder dispersion apparatus
US10245394B2 (en) 2006-10-25 2019-04-02 Mark Glusker Powder dispersion apparatus, method of making and using the apparatus, and components that can be used on the apparatus and other devices

Also Published As

Publication number Publication date
FR2516387B1 (enrdf_load_stackoverflow) 1984-06-29

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