FR2512447B1 - Nouveaux derives de n''-cyano n-oxydo-1 pyridinio-4 guanidine n'-substituee utiles comme medicaments antihypertenseurs et procede de leur preparation - Google Patents

Nouveaux derives de n''-cyano n-oxydo-1 pyridinio-4 guanidine n'-substituee utiles comme medicaments antihypertenseurs et procede de leur preparation

Info

Publication number
FR2512447B1
FR2512447B1 FR8215312A FR8215312A FR2512447B1 FR 2512447 B1 FR2512447 B1 FR 2512447B1 FR 8215312 A FR8215312 A FR 8215312A FR 8215312 A FR8215312 A FR 8215312A FR 2512447 B1 FR2512447 B1 FR 2512447B1
Authority
FR
France
Prior art keywords
oxydo
pyridinio
cyano
derivatives
novel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8215312A
Other languages
English (en)
Other versions
FR2512447A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Leo Pharma AS
Original Assignee
Leo Pharmaceutical Products Ltd AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leo Pharmaceutical Products Ltd AS filed Critical Leo Pharmaceutical Products Ltd AS
Publication of FR2512447A1 publication Critical patent/FR2512447A1/fr
Application granted granted Critical
Publication of FR2512447B1 publication Critical patent/FR2512447B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
FR8215312A 1981-09-10 1982-09-09 Nouveaux derives de n''-cyano n-oxydo-1 pyridinio-4 guanidine n'-substituee utiles comme medicaments antihypertenseurs et procede de leur preparation Expired FR2512447B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8127367 1981-09-10

Publications (2)

Publication Number Publication Date
FR2512447A1 FR2512447A1 (fr) 1983-03-11
FR2512447B1 true FR2512447B1 (fr) 1985-11-22

Family

ID=10524416

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8215312A Expired FR2512447B1 (fr) 1981-09-10 1982-09-09 Nouveaux derives de n''-cyano n-oxydo-1 pyridinio-4 guanidine n'-substituee utiles comme medicaments antihypertenseurs et procede de leur preparation

Country Status (16)

Country Link
JP (1) JPS5857363A (fr)
BE (1) BE894350A (fr)
CA (1) CA1177080A (fr)
CH (1) CH655500B (fr)
DE (1) DE3233380A1 (fr)
DK (1) DK157923C (fr)
FR (1) FR2512447B1 (fr)
GB (1) GB2105331B (fr)
GR (1) GR77009B (fr)
IE (1) IE54196B1 (fr)
IT (1) IT1156515B (fr)
LU (1) LU84375A1 (fr)
NL (1) NL8203214A (fr)
PH (1) PH18596A (fr)
SE (1) SE441357B (fr)
ZA (1) ZA825997B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5371086A (en) * 1991-03-15 1994-12-06 The Green Cross Corporation Aminopyridine compounds
JPH05294935A (ja) * 1991-03-15 1993-11-09 Green Cross Corp:The アミノピリジン系化合物
US8686002B2 (en) 2005-08-21 2014-04-01 AbbVie Deutschland GmbH & Co. KG Heterocyclic compounds and their use as binding partners for 5-HT5 receptors
WO2007022964A2 (fr) 2005-08-24 2007-03-01 Abbott Gmbh & Co. Kg Composes guanidine a substitution hetaryl et utilisation en tant que partenaires de liaison pour des recepteurs de 5-ht5

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3074955A (en) * 1960-11-30 1963-01-22 Us Vitamin Pharm Corp Pyridylalkyl dicyandiamides and guanylureas
US3329569A (en) * 1962-07-31 1967-07-04 Smith Kline French Lab Hypotensive compositions and methods of producing hypotension
FR2043491A1 (en) * 1969-05-30 1971-02-19 Ugine Kuhlmann Alpha-pyrid-4'-yl-benzylidene-aminoguani- - dines useful as hypotensives and spasmoly-tics
GB1489879A (en) * 1974-12-20 1977-10-26 Leo Pharm Prod Ltd N'-cyano-n'-3-pyridylguanidines
US4287346A (en) * 1979-02-16 1981-09-01 Eisai Co., Ltd. Cyanoguanidine derivatives

Also Published As

Publication number Publication date
DK398882A (da) 1983-03-11
PH18596A (en) 1985-08-15
SE441357B (sv) 1985-09-30
IE54196B1 (en) 1989-07-19
IE821918L (en) 1983-03-10
CH655500B (fr) 1986-04-30
SE8205107L (sv) 1983-03-11
ZA825997B (en) 1983-07-27
GB2105331A (en) 1983-03-23
DE3233380A1 (de) 1983-03-17
GB2105331B (en) 1985-05-01
DK157923C (da) 1990-08-06
LU84375A1 (fr) 1983-06-07
BE894350A (fr) 1983-03-09
FR2512447A1 (fr) 1983-03-11
JPS5857363A (ja) 1983-04-05
GR77009B (fr) 1984-09-04
SE8205107D0 (sv) 1982-09-08
IT8268075A0 (it) 1982-09-09
CA1177080A (fr) 1984-10-30
IT1156515B (it) 1987-02-04
DK157923B (da) 1990-03-05
NL8203214A (nl) 1983-04-05

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Legal Events

Date Code Title Description
TP Transmission of property
ST Notification of lapse