FR2508486A1 - Methode de dosage immuno-enzymatique et trousse pour sa mise en oeuvre - Google Patents

Methode de dosage immuno-enzymatique et trousse pour sa mise en oeuvre Download PDF

Info

Publication number
FR2508486A1
FR2508486A1 FR8211366A FR8211366A FR2508486A1 FR 2508486 A1 FR2508486 A1 FR 2508486A1 FR 8211366 A FR8211366 A FR 8211366A FR 8211366 A FR8211366 A FR 8211366A FR 2508486 A1 FR2508486 A1 FR 2508486A1
Authority
FR
France
Prior art keywords
enzyme
antibody
substance
substantially inactive
conjugate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR8211366A
Other languages
English (en)
French (fr)
Other versions
FR2508486B1 (OSRAM
Inventor
Richard Julian Stuart Duncan
Peter David Weston
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Publication of FR2508486A1 publication Critical patent/FR2508486A1/fr
Application granted granted Critical
Publication of FR2508486B1 publication Critical patent/FR2508486B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
    • C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
    • C12Y302/01023—Beta-galactosidase (3.2.1.23), i.e. exo-(1-->4)-beta-D-galactanase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2468—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1) acting on beta-galactose-glycoside bonds, e.g. carrageenases (3.2.1.83; 3.2.1.157); beta-agarase (3.2.1.81)
    • C12N9/2471—Beta-galactosidase (3.2.1.23), i.e. exo-(1-->4)-beta-D-galactanase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/745—Assays involving non-enzymic blood coagulation factors
    • G01N2333/75—Fibrin; Fibrinogen

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
FR8211366A 1981-06-30 1982-06-29 Methode de dosage immuno-enzymatique et trousse pour sa mise en oeuvre Granted FR2508486A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8120149 1981-06-30

Publications (2)

Publication Number Publication Date
FR2508486A1 true FR2508486A1 (fr) 1982-12-31
FR2508486B1 FR2508486B1 (OSRAM) 1984-12-28

Family

ID=10522902

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8211366A Granted FR2508486A1 (fr) 1981-06-30 1982-06-29 Methode de dosage immuno-enzymatique et trousse pour sa mise en oeuvre

Country Status (4)

Country Link
JP (1) JPS587561A (OSRAM)
DE (1) DE3224217A1 (OSRAM)
FR (1) FR2508486A1 (OSRAM)
GB (1) GB2102946B (OSRAM)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986001298A1 (fr) * 1984-08-14 1986-02-27 Diagnostica Stago Procede de dosage de produits de degradation du fibrinogene
EP0088974A3 (en) * 1982-03-18 1986-05-28 Miles Inc. Homogeneous immunoassay with labelled monoclonal anti-analyte

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5847491A (ja) * 1981-09-18 1983-03-19 Ajinomoto Co Inc β−Ｄ−ガラクトシダ−ゼ作用の停止方法
DE3362399D1 (en) * 1982-05-24 1986-04-10 Miles Lab Improved homogeneous binding assay method and reagent system, test kit and test device therefor
AU559576B2 (en) * 1983-01-31 1987-03-12 Boots-Celltech Diagnostics Limited Immunoassay
JPS59178361A (ja) * 1983-03-29 1984-10-09 Fujirebio Inc 抗原決定基具有物質測定法
JPS59178360A (ja) * 1983-03-29 1984-10-09 Fujirebio Inc 抗原決定基具有物質測定方法
JPS59164960A (ja) * 1983-03-11 1984-09-18 Fujirebio Inc 抗原決定基具有物質の測定法
JPS59194906A (ja) * 1983-04-15 1984-11-05 株式会社荏原製作所 空気輸送装置の投入シユ−ト
DE3430905A1 (de) * 1984-08-22 1986-02-27 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur bestimmung einer immunologisch bindefaehigen substanz
US4629689A (en) * 1984-08-29 1986-12-16 Allied Corporation Binding assay with amplified read-out and gas-phase detection
JPH0728043U (ja) * 1993-11-01 1995-05-23 公之 宿岩 容器立て
GB2511761A (en) * 2013-03-11 2014-09-17 Cancer Rec Tech Ltd Methods for detecting molecules in a sample

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2301823A1 (fr) * 1975-02-20 1976-09-17 Syva Co Essai immunologique de determination d'une polyiodothyronine
GB2001172A (en) * 1977-07-14 1979-01-24 Syva Co Competitive protein binding assay

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2301823A1 (fr) * 1975-02-20 1976-09-17 Syva Co Essai immunologique de determination d'une polyiodothyronine
GB2001172A (en) * 1977-07-14 1979-01-24 Syva Co Competitive protein binding assay

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, vol. 93, no. 15, 13 octobre 1980, page 343, no. 145778q, Columbus Ohio (USA); *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0088974A3 (en) * 1982-03-18 1986-05-28 Miles Inc. Homogeneous immunoassay with labelled monoclonal anti-analyte
WO1986001298A1 (fr) * 1984-08-14 1986-02-27 Diagnostica Stago Procede de dosage de produits de degradation du fibrinogene

Also Published As

Publication number Publication date
GB2102946B (en) 1984-11-28
GB2102946A (en) 1983-02-09
DE3224217A1 (de) 1983-01-13
JPS587561A (ja) 1983-01-17
FR2508486B1 (OSRAM) 1984-12-28

Similar Documents

Publication Publication Date Title
Sugiyama et al. Telmisartan inhibits both oxidative stress and renal fibrosis after unilateral ureteral obstruction in acatalasemic mice
FR2508486A1 (fr) Methode de dosage immuno-enzymatique et trousse pour sa mise en oeuvre
EP0041426B1 (fr) Produit de couplage entre une lectine et un ligand spécifique, obtention et application dans le domaine biologique
EP0080401B1 (fr) Nouveaux médicaments anticancéreux pour le traitement des leucémies T constitués de la chaine A de la ricine et d'un anticorps monoclonal spécifique
CH688194A5 (fr) Composition stabilisée de troponine pour immunoessais et procédé de stabilisation de troponine pour immunoessais.
EP2962105A1 (en) Methods and reagents for determining isomeric analytes
FR2500009A1 (fr) Procede et systeme de necessaire experimental diagnostique pour determiner quantitativement la presence de la forme isoenzymatique mb de la creatine kinase
JPH09507754A (ja) 哺乳類悪性細胞の選択的メチオニン飢餓方法
Gupta et al. Triosephosphate isomerase from young and old Turbatrix aceti
EP0139552B1 (fr) Composé marqué par l'acétylcholinestérase d'electrophorus electricus, son procédé de préparation et son utilisation comme marqueur dans des dosages enzymo-immunologiques
CH628739A5 (en) Process of immunological assay using a bound enzyme, and means for implementing the process
CH644455A5 (fr) Procede d'analyse quantitative des nucleotides cycliques et ensemble de reactifs pour la mise en oeuvre de ce procede.
FR2601781A1 (fr) Reactif de dosage de mycotoxine et methode l'utilisant pour doser une mycotoxine
FR2709492A1 (fr) Méthode d'immunodosage spécifique de la glutathion peroxydase plasmatique humaine, kit pour sa mise en Óoeuvre, oligopeptides et anticorps spécifiques de la méthode .
EP0065320B1 (fr) Procédé de couplage d'un médicament avec un composé polypeptidique thiolé provenant d'un fragment de la toxine tétanique et ses applications
JP3154724B2 (ja) 下痢性貝毒に特異的なモノクローナル抗体、ハイブリドーマ及び下痢性貝毒の検出方法
FR2525475A1 (fr) Antigenes de la leucemie des cellules t de l'adulte, procedes pour leur preparation et pour le dosage d'anticorps contre ces antigenes
EP0007879B1 (fr) Delta-5,3-céto stéroide isomérase et son application dans les dosages immunoenzymatiques
Garg et al. Suppression of ouabain-insensitive K-ATPase activity in rabbit nephron segments during chronic hyperkalemia
EP0426552B1 (fr) Composition de peroxydase stabilisée, utilisable pour des essais immuno-enzymatiques
FR2748812A1 (fr) Trousse de diagnostic et procede pour determiner la concentration d'un cytochrome p450
RU2416094C1 (ru) Набор для количественного определения авермектинов методом одностадийного конкурентного иммуноферментного анализа
EP0785432B1 (fr) Procédé pour l'identification ou le dosage immunologique d'antigènes polypeptidiques
EP0345100A1 (fr) Préparation de récepteurs du PAF et méthode de dosage du PAF
EP0192565A1 (fr) Procédé de dosage immunologique des amines, anticorps monoclonaux et ensemble de réactifs pour la mise en oeuvre du procédé

Legal Events

Date Code Title Description
ST Notification of lapse