FR2484258A1 - Agent immunotherapique pour tumeurs, avec du lipopolysaccharide comme composant actif, et procede de preparation de cet agent - Google Patents
Agent immunotherapique pour tumeurs, avec du lipopolysaccharide comme composant actif, et procede de preparation de cet agent Download PDFInfo
- Publication number
- FR2484258A1 FR2484258A1 FR8012794A FR8012794A FR2484258A1 FR 2484258 A1 FR2484258 A1 FR 2484258A1 FR 8012794 A FR8012794 A FR 8012794A FR 8012794 A FR8012794 A FR 8012794A FR 2484258 A1 FR2484258 A1 FR 2484258A1
- Authority
- FR
- France
- Prior art keywords
- lipopolysaccharide
- fatty acid
- strain
- tumors
- arabinomannan
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP8468179A JPS568320A (en) | 1979-07-04 | 1979-07-04 | Drug for tumor immunotherapy comprising lipopolysaccharide as active constituent |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2484258A1 true FR2484258A1 (fr) | 1981-12-18 |
| FR2484258B1 FR2484258B1 (enExample) | 1984-11-30 |
Family
ID=13837428
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR8012794A Granted FR2484258A1 (fr) | 1979-07-04 | 1980-06-09 | Agent immunotherapique pour tumeurs, avec du lipopolysaccharide comme composant actif, et procede de preparation de cet agent |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US4329452A (enExample) |
| JP (1) | JPS568320A (enExample) |
| CA (1) | CA1132047A (enExample) |
| CH (1) | CH650799A5 (enExample) |
| ES (1) | ES493061A0 (enExample) |
| FR (1) | FR2484258A1 (enExample) |
| IT (1) | IT1132168B (enExample) |
| SU (1) | SU1232124A3 (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2542012A1 (fr) * | 1983-03-04 | 1984-09-07 | Maruyama Chisato | Lipopolysaccharide et procede pour sa preparation |
| EP0295749A1 (en) * | 1987-06-15 | 1988-12-21 | Duphar International Research B.V | Sulpholipopolysaccharides as stimulators of the non-specific defence mechanism |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5718619A (en) * | 1980-07-10 | 1982-01-30 | Chisato Maruyama | Tumor immunotherapy agent containing lipopolysaccharide as active principle |
| US4612304A (en) * | 1985-06-11 | 1986-09-16 | Ss Pharmaceutical Co., Ltd. | Antitumor formulation containing lipopolysaccharide with trehalose derivatives |
| US4818751A (en) * | 1985-07-02 | 1989-04-04 | Zeria Shinyaku Kogyo Kabushiki Kaisha | Cosmetics |
| US4798369A (en) * | 1987-11-03 | 1989-01-17 | The Firestone Tire & Rubber Company | Ultrasonic air spring system |
| US5853737A (en) * | 1992-12-10 | 1998-12-29 | Brigham And Women's Hospital | Method for inducing a CD1-restricted immune response |
| US6238676B1 (en) * | 1992-12-10 | 2001-05-29 | Brigham And Women's Hospital | Presentation of hydrophobic antigens to T-cells by CD1 molecules |
| US7063844B2 (en) | 1992-12-10 | 2006-06-20 | The Brigham And Women's Hospital, Inc. | Presentation of hydrophobic antigens to T-cells by CD1 molecules |
| US5712123A (en) * | 1994-10-07 | 1998-01-27 | Board Of Trustees Of The University Of Illinois | Mixture having antitumor activities |
| WO1998056941A1 (en) * | 1995-12-12 | 1998-12-17 | Tai Ho Chung | Carbohydrate complex extracted from mycobacterium tuberculosis and process for the preparation thereof |
| US5869645A (en) * | 1997-10-15 | 1999-02-09 | Board Of Trustees Of The University Of Illinois | Method for isolating high molecular weight antineoplastic glycans using urea |
| NZ505538A (en) * | 2000-07-03 | 2004-12-24 | Malaghan Inst Of Medical Res | A vaccine comprising immunogenic acyl glyceryl phosphatidylinositol manno-oligosaccharide (PIM); and the use of PIM for inducing an immune response in a patient effective in the prevention or treatment of Th2-mediated diseases or disorders such as asthma |
| US8034359B2 (en) | 2004-06-07 | 2011-10-11 | Qu Biologics Inc. | Tissue targeted antigenic activation of the immune response to cancers |
| US8501198B2 (en) | 2004-06-07 | 2013-08-06 | Qu Biologics Inc. | Tissue targeted antigenic activation of the immune response to treat cancers |
| PL1765391T3 (pl) * | 2004-06-07 | 2013-08-30 | Qu Biologics Inc | Kompozycje bakteryjne do leczenia nowotworów |
| US9107864B2 (en) | 2004-06-07 | 2015-08-18 | Qu Biologics Inc. | Tissue targeted antigenic activation of the immune response to treat cancers |
| US20070161546A1 (en) * | 2005-12-15 | 2007-07-12 | Colm King | Methods and compositions for treatment of cancer |
| US8980279B2 (en) | 2010-07-26 | 2015-03-17 | Qu Biologics | Personalized site-specific immunomodulation |
| JP2015157763A (ja) * | 2012-05-28 | 2015-09-03 | エヌエーアイ株式会社 | 認知症の治療剤及び予防剤 |
| EP3125763A4 (en) | 2014-03-31 | 2017-12-13 | University of Utah Research Foundation | Fluid analysis device and associated systems and methods |
| CA3254723A1 (en) | 2014-05-02 | 2025-04-15 | Qu Biologics Inc | ANTIMICROBIAL IMMUNOMODULATION |
| EP4226939A4 (en) * | 2020-10-09 | 2024-11-13 | Zeria Pharmaceutical Co., Ltd. | NEW USE OF A MYCOBACTERIUM TUBERCULOSIS EXTRACT |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2227862A1 (en) * | 1973-05-04 | 1974-11-29 | Anvar | Non-arthrogenic immunological adjuvants - obtained by extraction of lipid-free mycobacterial residues |
| FR2275224A1 (fr) * | 1974-06-20 | 1976-01-16 | Anvar | Fractions mycobacteriennes utilisables comme agent anti-infectieux, et procede pour leur preparation |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1188519A (en) * | 1966-10-27 | 1970-04-15 | Wellcome Found | Method for the Purification of Lipopolysaccharides |
| NL7308450A (enExample) * | 1972-06-20 | 1973-12-27 |
-
1979
- 1979-07-04 JP JP8468179A patent/JPS568320A/ja active Granted
-
1980
- 1980-05-06 US US06/147,127 patent/US4329452A/en not_active Expired - Lifetime
- 1980-06-09 FR FR8012794A patent/FR2484258A1/fr active Granted
- 1980-07-03 CA CA355,290A patent/CA1132047A/en not_active Expired
- 1980-07-03 CH CH5128/80A patent/CH650799A5/de not_active IP Right Cessation
- 1980-07-03 SU SU802943651A patent/SU1232124A3/ru active
- 1980-07-03 IT IT23219/80A patent/IT1132168B/it active
- 1980-07-03 ES ES493061A patent/ES493061A0/es active Granted
-
1981
- 1981-08-18 US US06/293,999 patent/US4394502A/en not_active Expired - Lifetime
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2227862A1 (en) * | 1973-05-04 | 1974-11-29 | Anvar | Non-arthrogenic immunological adjuvants - obtained by extraction of lipid-free mycobacterial residues |
| FR2275224A1 (fr) * | 1974-06-20 | 1976-01-16 | Anvar | Fractions mycobacteriennes utilisables comme agent anti-infectieux, et procede pour leur preparation |
Non-Patent Citations (2)
| Title |
|---|
| EXPERIENTIA, vol. 31, no. 8, 15 août 1975, pages 983-85, Basel (CH); * |
| MOLECULAR & CELLULAR BIOCHEMISTRY, vol. 7, no. 2, 30 mai 1975, pages 87-104, La Haye (NL); * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2542012A1 (fr) * | 1983-03-04 | 1984-09-07 | Maruyama Chisato | Lipopolysaccharide et procede pour sa preparation |
| EP0295749A1 (en) * | 1987-06-15 | 1988-12-21 | Duphar International Research B.V | Sulpholipopolysaccharides as stimulators of the non-specific defence mechanism |
Also Published As
| Publication number | Publication date |
|---|---|
| CH650799A5 (de) | 1985-08-15 |
| ES8105783A1 (es) | 1981-06-16 |
| US4329452A (en) | 1982-05-11 |
| JPS568320A (en) | 1981-01-28 |
| JPS6256843B2 (enExample) | 1987-11-27 |
| IT8023219A0 (it) | 1980-07-03 |
| CA1132047A (en) | 1982-09-21 |
| US4394502A (en) | 1983-07-19 |
| ES493061A0 (es) | 1981-06-16 |
| SU1232124A3 (ru) | 1986-05-15 |
| FR2484258B1 (enExample) | 1984-11-30 |
| IT1132168B (it) | 1986-06-25 |
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