ES8105783A1 - Un procedimiento para preparar un lipopolisacarido - Google Patents

Un procedimiento para preparar un lipopolisacarido

Info

Publication number
ES8105783A1
ES8105783A1 ES493061A ES493061A ES8105783A1 ES 8105783 A1 ES8105783 A1 ES 8105783A1 ES 493061 A ES493061 A ES 493061A ES 493061 A ES493061 A ES 493061A ES 8105783 A1 ES8105783 A1 ES 8105783A1
Authority
ES
Spain
Prior art keywords
lipopolysaccharide
tumors
active component
immunotherapeutic agent
disclosed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES493061A
Other languages
English (en)
Other versions
ES493061A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of ES8105783A1 publication Critical patent/ES8105783A1/es
Publication of ES493061A0 publication Critical patent/ES493061A0/es
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR LIPOPOLISACARIDOS QUE TENGAN ACTIVIDAD ANTITUMORAL INMUNOLOGICA. CONSISTE EN EXTRAER CON AGUA CALIENTE EL CUERPO CELULAR DEL BACILO DE TUBERCULOSIS HUMANA Y PURIFICAR, MEDIANTE PURIFICACION FRACCIONADA, EL COMPONENTE LIPOPOLISACARIDO RECUPERADO, CON LO QUE SE OBTIENE HIPOARABINOMANANA, O ARABINOMANANA EXENTA DE LIPIDO QUE ES MODIFICADA CON UN ACIDO GRASO A LIPOARABINOMANANA.
ES493061A 1979-07-04 1980-07-03 Un procedimiento para preparar un lipopolisacarido Granted ES493061A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8468179A JPS568320A (en) 1979-07-04 1979-07-04 Drug for tumor immunotherapy comprising lipopolysaccharide as active constituent

Publications (2)

Publication Number Publication Date
ES8105783A1 true ES8105783A1 (es) 1981-06-16
ES493061A0 ES493061A0 (es) 1981-06-16

Family

ID=13837428

Family Applications (1)

Application Number Title Priority Date Filing Date
ES493061A Granted ES493061A0 (es) 1979-07-04 1980-07-03 Un procedimiento para preparar un lipopolisacarido

Country Status (8)

Country Link
US (2) US4329452A (es)
JP (1) JPS568320A (es)
CA (1) CA1132047A (es)
CH (1) CH650799A5 (es)
ES (1) ES493061A0 (es)
FR (1) FR2484258A1 (es)
IT (1) IT1132168B (es)
SU (1) SU1232124A3 (es)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5718619A (en) * 1980-07-10 1982-01-30 Chisato Maruyama Tumor immunotherapy agent containing lipopolysaccharide as active principle
JPS59161320A (ja) * 1983-03-04 1984-09-12 Maruyama Chisato リポ多糖体およびその製造法
US4612304A (en) * 1985-06-11 1986-09-16 Ss Pharmaceutical Co., Ltd. Antitumor formulation containing lipopolysaccharide with trehalose derivatives
US4818751A (en) * 1985-07-02 1989-04-04 Zeria Shinyaku Kogyo Kabushiki Kaisha Cosmetics
DK316188A (da) * 1987-06-15 1988-12-16 Duphar Int Res Sulfolipopolysaccharider som stimolatorer for den ikke specifikke forsvarsmekanisme
US4798369A (en) * 1987-11-03 1989-01-17 The Firestone Tire & Rubber Company Ultrasonic air spring system
US5853737A (en) * 1992-12-10 1998-12-29 Brigham And Women's Hospital Method for inducing a CD1-restricted immune response
US7063844B2 (en) 1992-12-10 2006-06-20 The Brigham And Women's Hospital, Inc. Presentation of hydrophobic antigens to T-cells by CD1 molecules
US6238676B1 (en) * 1992-12-10 2001-05-29 Brigham And Women's Hospital Presentation of hydrophobic antigens to T-cells by CD1 molecules
US5712123A (en) * 1994-10-07 1998-01-27 Board Of Trustees Of The University Of Illinois Mixture having antitumor activities
ES2205226T3 (es) * 1997-06-10 2004-05-01 Tai Ho Chung Complejo de carbohidratos extraido de mycobacterium tuberculosis y procedimiento para la preparacion del mismo.
US5869645A (en) * 1997-10-15 1999-02-09 Board Of Trustees Of The University Of Illinois Method for isolating high molecular weight antineoplastic glycans using urea
NZ505538A (en) * 2000-07-03 2004-12-24 Malaghan Inst Of Medical Res A vaccine comprising immunogenic acyl glyceryl phosphatidylinositol manno-oligosaccharide (PIM); and the use of PIM for inducing an immune response in a patient effective in the prevention or treatment of Th2-mediated diseases or disorders such as asthma
US8034359B2 (en) 2004-06-07 2011-10-11 Qu Biologics Inc. Tissue targeted antigenic activation of the immune response to cancers
AU2005251397B2 (en) * 2004-06-07 2010-11-11 Qu Biologics Inc. Bacterial compositions for the treatment of cancer
US8501198B2 (en) 2004-06-07 2013-08-06 Qu Biologics Inc. Tissue targeted antigenic activation of the immune response to treat cancers
US9107864B2 (en) 2004-06-07 2015-08-18 Qu Biologics Inc. Tissue targeted antigenic activation of the immune response to treat cancers
WO2007078615A2 (en) * 2005-12-15 2007-07-12 Cavit Sciences, Inc Methods and compositions for treatment of cancer
US8980279B2 (en) 2010-07-26 2015-03-17 Qu Biologics Personalized site-specific immunomodulation
JP2015157763A (ja) * 2012-05-28 2015-09-03 エヌエーアイ株式会社 認知症の治療剤及び予防剤
JP2017511480A (ja) 2014-03-31 2017-04-20 ユニヴァーシティー オブ ユタ リサーチ ファウンデーション 液解析デバイスならびに関連するシステムおよび方法
RU2020120075A (ru) 2014-05-02 2020-07-03 Кью Байолоджикс Инк. Противомикробная иммуномодуляция
BR112023006220A2 (pt) * 2020-10-09 2023-05-09 Zeria Pharm Co Ltd Uso do extrato de mycobacterium tuberculosis

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1188519A (en) * 1966-10-27 1970-04-15 Wellcome Found Method for the Purification of Lipopolysaccharides
FR2227862A1 (en) * 1973-05-04 1974-11-29 Anvar Non-arthrogenic immunological adjuvants - obtained by extraction of lipid-free mycobacterial residues
NL7308450A (es) * 1972-06-20 1973-12-27
DE2527636A1 (de) * 1974-06-20 1976-01-08 Anvar Verfahren zur herstellung von mycobakteriellen fraktionen

Also Published As

Publication number Publication date
JPS6256843B2 (es) 1987-11-27
CH650799A5 (de) 1985-08-15
JPS568320A (en) 1981-01-28
US4329452A (en) 1982-05-11
FR2484258A1 (fr) 1981-12-18
IT1132168B (it) 1986-06-25
US4394502A (en) 1983-07-19
FR2484258B1 (es) 1984-11-30
IT8023219A0 (it) 1980-07-03
CA1132047A (en) 1982-09-21
ES493061A0 (es) 1981-06-16
SU1232124A3 (ru) 1986-05-15

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